This is an archive of papers published by the staff and faculty of Fox Chase Cancer Center. For questions about content, please contact Talbot Research Library
Last updated on
Padanilam BJ , Stadler HS , Mills KA , McLeod LB , Solursh M , Lee B , Ramirez F , Buetow KH , Murray JC
Characterization of the human HOX 7 cDNA and identification of polymorphic markers
Human Molecular Genetics. 1992 ;1(6) :407-410
AbstractcDNA clones for a human HOX 7 gene obtained with homologous clones of Drosophila were used in human gene mapping studies. The human cDNA clone was isolated from a library constructed from human embryonic craniofacial material. The sequence of the cDNA demonstrates significant homology with mouse HOX 7. A search for RFLPs identified MboII and BstEII variants. A CA dinucleotide repeat with 5 alleles was also identified and allowed placement of HOX 7 into a defined linkage map. Evidence for linkage disequilibrium was found with markers tested. These results place the human HOX 7 gene in a defined position on 4p.
Notes09646906 (ISSN) Cited By: 29; Export Date: 31 May 2006; Source: Scopus CODEN: HMGEE Language of Original Document: English Correspondence Address: Padanilam, B.J.; Department of Biology; University of Iowa Iowa City, IA 52242, United States Molecular Sequence Numbers: GENBANK: M88632, M88633, M88634, M88635, M88636, M88637, M97676, X64597, X64598, X64599; Chemicals/CAS: DNA, 9007-49-2; RNA, 63231-63-0, Deoxyribonucleases, Type II Site-Specific, EC 126.96.36.199; DNA, 9007-49-2; endodeoxyribonuclease EcaI, EC 3.1.21.-; endodeoxyribonuclease MboII, EC 3.1.21.-; Oligodeoxyribonucleotides; RNA, 63231-63-0