FCCC LOGO Faculty Publications
Rajagopalan JS , Jaffe EK
Microbial production and NMR characterization of [2,6,9-13C]chorismate and [1,3,5,8-13C]chorismate
Bioorganic and Medicinal Chemistry Letters. 1993 ;3(7) :1453-1456
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Abstract
Chorismate is a biosynthetic precursor of the aromatic amino acids and many natural products. [2,6,9-13C]Chorismate and [1,3,5,8-13C]chorismate have been prepared microbially from [1-13C]glucose and [2-13C]glucose, respectively, using the culture filtrates of Klebsiella pneumoniae strain 62-1. This is an inexpensive, time saving and easy method in comparison to other published methods for the preparation of selectively 13C-labelled chorismate.
Notes
0960894X (ISSN) Cited By: 1; Export Date: 31 May 2006; Source: Scopus CODEN: BMCLE; DOI: 10.1016/S0960-894X(01)80428-5 Language of Original Document: English Correspondence Address: Jaffe, E.K.; Institute for Cancer Research; Fox Chase Cancer Center Philadelphia, PA 19111, United States Chemicals/CAS: carbon 13, 14762-74-4; chorismic acid, 617-12-9