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Pass HI , Robinson BW , Testa JR , Carbone M
Emerging translational therapies for mesothelioma
Chest. 1999 Dec;116(6) :455S-460S
AbstractMalignant pleural mesothelioma remains a therapeutic. and diagnostic problem. Translational mechanisms for treatment of the disease are emerging from newly learned characteristics of the tumor on a molecular, cellular, and extracellular basis. Although slow to reach the clinical arena, these potential strategies do show proof of principle in the in vitro and in vivo settings, and some, including adenoviral molecular chemotherapy, have completed phase I testing. This review describes the rationale and status of these newer treatment ideas.
NotesTimes Cited: 6 English Article S 268AE CHEST