This is an archive of papers published by the staff and faculty of Fox Chase Cancer Center. For questions about content, please contact Talbot Research Library
Last updated on
Juo SHH , Pugh EW , Baffoe-Bonnie A , Kingman A , Sorant AJM , Klein AP , O'Neill J , Mathias RA , Wilson AF , Bailey-Wilson JE
Possible linkage of alcoholism, monoamine oxidase activity and p300 amplitude to markers on chromosome 12q24
Genetic Epidemiology. 1999 ;17 :S193-S198
AbstractMultipoint linkage analysis was used to screen for evidence of linkage between alcoholism and five alcoholism-related quantitative traits. The results suggest that a susceptibility locus that influences monoamine oxidase activity and P300 amplitude at the Pt lead, and increases the risk of alcohol dependence may be linked to markers in the 12q24 region. Furthermore, the susceptibility for alcoholism may be associated with allele 3 (allele size 144) of D12S392. (C) 1999 Wiley-Liss, Inc.
NotesTimes Cited: 2 English Article 1 260JM GENET EPIDEMIOL