FCCC LOGO Faculty Publications
Moloshok TD , Datta D , Kossenkov AV , Ochs MF
Bayesian decomposition classification of the project normal data set
Methods of Microarray Data Analysis III, Papers from CAMDA '02, 3rd, Durham, NC, United States, Nov. 14-15, 2002. 2003 :211-231
PMID: AN 2003:990348   
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Abstract
The process of development and maintenance of tissues is complex. Key genes have been identified that serve as master switches during development, regulating numerous other genes and guiding differentiation and the development of complex structures. Within cells comprising different tissue types, the genomic complements of genes remain the same. Understanding what differentiates one tissue from another requires a different level of anal., one performed at a functional rather than structural level. We have used a new version of the Bayesian Decompn. algorithm to identify tissue specific expression. The expression patterns which result were analyzed in terms of the ontol. information on the processes in which a gene is involved by exploration of the Gene Ontol. database using automated software for data retrieval and anal. [on SciFinder (R)]
Notes
CAN 140:176180 3-6 Biochemical Genetics Division of Basic Science,Fox Chase Cancer Center,Philadelphia,PA,USA. Conference written in English.