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Bookman MA , Greer BE , Ozols RF
Optimal therapy of advanced ovarian cancer: carboplatin and paclitaxel vs. cisplatin and paclitaxel (GOG158) and an update on GOG0 182-ICON5
International Journal of Gynecological Cancer. 2003 Nov-Dec;13(6) :735-740
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Mature results from GOG158 have clearly established carboplatin and paclitaxel as an effective and well tolerated standard regimen, providing a basis for the reference arm in GOG0182-ICON5, an ongoing multiarmed phase III trial of the Gynecologic Cancer InterGroup (GCIG) evaluating the incorporation of newer cytotoxic agents. Results from GOG158 will be reviewed, including an analysis of second-look surgical outcomes, followed by an update on the current status of GOG0182-ICON5.
English Review Bookman, MA; *Fox* *Chase* Canc Ctr, Div Med Sci, 7701 Burholme Ave, Philadelphia, PA 19111 USA. Research Addresses: *Fox* *Chase* Canc Ctr, Div Med Sci, Philadelphia, PA 19111 USA. Univ Washington, Sch Med, Div Gynecol Oncol, Seattle, WA USA. Cited References: PARMAR MKB, 2002, LANCET, V360, P505 BOOKMAN MA, 2003, J CLIN ONCOL, V21, PS149 BOOKMAN MA, 1996, J CLIN ONCOL, V14, P1895 DUBOIS A, 1999, P AN M AM SOC CLIN, V18, P1374 GREER BE, 2003, GYNECOL ONCOL, V88, P156 MCGUIRE WP, 1996, NEW ENGL J MED, V334, P1 MUGGIA FM, 2000, J CLIN ONCOL, V18, P106 NEIJT JP, 2000, J CLIN ONCOL, V18, P3084 OZOLS RF, 1999, P AN M AM SOC CLIN, V18, P1373 OZOLS RF, 2003, J CLIN ONCOL, V21, P3194 PICCART MJ, 2000, J NATL CANCER I, V92, P699 VERMORKEN JB, 1993, ANN ONCOL, V4, P41 Number of cited references: 12 Number of times cited: 0 Publisher: BLACKWELL PUBLISHING INC; 350 MAIN ST, MALDEN, MA 02148 USA. 1048-891X