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Chapman JDonald , Schneider Richard F , Engelhardt Edward L
1,4,8,11-Tetraazacyclotetradecane derivatives as radiodiagnostic agents and their use in determining hypoxia and radioresistance of tumors
. 2000 20000126. :30 pp
PMID: AN 2000:513502   
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Abstract
1,4,8,11-Tetraazacyclotetradecane which is chem. linked to from one to four nitroimidazole groups provides an effective radiodiagnostic agent for detg. tissue hypoxia and radioresistance of tumor tissue. [on SciFinder (R)]
Notes
CAN 133:131882 8-9 Radiation Biochemistry Patent written in English. 20000727 295-37-4 (1,4,8,11-Tetraazacyclotetradecane); 13551-90-1 Role: RCT (Reactant), RACT (Reactant or reagent) (prepn. of complexes of radionuclides with tetraazacyclotetradecane derivs. as radiodiganostic agents and their use in detg. hypoxia and radioresistance of tumors); 286375-06-2P; 286429-20-7P Role: SPN (Synthetic preparation), PREP (Preparation) (prepn. of complexes of radionuclides with tetraazacyclotetradecane derivs. as radiodiganostic agents and their use in detg. hypoxia and radioresistance of tumors); 13981-25-4DP (Copper-64); 14092-99-0DP (Manganese-52); 14093-04-0DP (Iron-52); 14119-09-6DP (Gallium-67); 14133-76-7DP (Technetium-99); 14276-53-0DP (Copper-62); 14392-02-0DP (Chromium-51); 14687-25-3DP (Lead-203); 14885-78-0DP (Indium-113); 15750-15-9DP (Indium-111); 15755-33-6DP (Arsenic-72); 15757-14-9DP (Gallium-68); 15757-86-5DP (Copper-67); 15758-35-7DP (Ruthenium-97); 286429-18-3P; 286429-19-4P Role: SPN (Synthetic preparation), THU (Therapeutic use), BIOL (Biological study), PREP (Preparation), USES (Uses) (prepn. of complexes of radionuclides with tetraazacyclotetradecane derivs. as radiodiganostic agents and their use in detg. hypoxia and radioresistance of tumors) A1 US 99-117253 19990126