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Kruisbeek AM , Haks MC , Carleton M , Michie AM , Zuniga-Pflucker JC , Wiest DL
Branching out to gain control: how the pre-TCR is linked to multiple functions
Immunology Today. 2000 Dec;21(12) :637-644
AbstractHow is signaling specificity achieved by the pre-TCR during selection of T-cell fate? Like the TCR, this receptor controls many functions, and recent studies define which pathways couple the pre-TCR to the molecular events controlling survival, proliferation, allelic exclusion at the TCR beta locus, and further differentiation.
NotesTimes Cited: 19 English Review 383AB IMMUNOL TODAY