This is an archive of papers published by the staff and faculty of Fox Chase Cancer Center. For questions about content, please contact Talbot Research Library
Last updated on
Tapiero H , Tew KD , Gate L , Machover D
Prevention of pathologies associated with oxidative stress and dietary intake deficiencies: folate deficiency and requirements
Biomed Pharmacother. 2001 Sep;55(7) :381-90
PMID: 11669501 URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11669501
AbstractFolate (folic acid, folacin) is an essential vitamin that is found in nature. Folates contain the core chemical structure of pteroylglutamic acid, but vary in their state of reduction, the single carbon moiety they bear and/or the length of the glutamate chain. At least 50% of whole body folate is stored in the liver. The influence of intracellular folate concentration depends largely on dietary intake. The supply of folate depends primarily on the quantity and bioavailability of ingested folate and the rate of loss by urinary and fecal routes and through catabolism.
Notes21525671 0753-3322 Journal Article Review Review, Tutorial