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Mathews KD , Mills KA , Bosch EP , Ionasescu VV , Wiles KR , Buetow KH , Murray JC
Linkage Localization of Facioscapulohumeral Muscular-Dystrophy (Fshd) in 4q35
American Journal of Human Genetics. 1992 Aug;51(2) :428-431
AbstractFasioscapulohumeral muscular dystrophy (FSHD) has recently been localized to 4q35. We have studied four families with FSHD. Linkage to the 4q35 probes D4S163, D4S139, and D4S171 was confirmed. We found no recombinants helpful in detailed localization of the FSHD gene. Two of our families include males with a rapidly progressive muscle disease that had been diagnosed, on the basis of clinical features, as Duchenne muscular dystrophy. One of these males is available for linkage study and shares the haplotype of his FSHD-affected aunt and cousin.
NotesEnglish Article JF776 AMER J HUM GENET