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Buetow KH , Weber JL , Ludwigsen S , Scherpbierheddema T , Duyk GM , Sheffield VC , Wang ZY , Murray JC
Integrated Human Genome-Wide Maps Constructed Using the Ceph Reference Panel
Nature Genetics. 1994 Apr;6(4) :391-393
PMID: ISI:A1994ND87000019   
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High resolution linkage maps have proven to be invaluable tools in genetic investigations. We have assembled a collection of genetic maps constructed from primary data collected from investigators performing genotyping using the Centre Etude Polymorphism Humain (CEPH) reference pedigree panel. These maps were constructed using a rigorous, semi-automated map construction algorithm that evaluates the integrity of the maps during construction. Two classes of maps were produced: a high confidence ''skeletal'' set composed of 544 PCR based markers, and a more highly annotated ''framework'' set containing maps of 1,123 markers. Genetic map locations within the framework maps are provided for an additional 1,758 loci without statistically unique interval assignments.
English Article ND870 NAT GENET