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Paudel R , Ferrante S , Qi J , Dunn RL , Berry DL , Semerjian A , Brede CM , George AK , Lane BR , Ginsburg KB , Montie JE , Lane GI
Patient preferences and treatment decisions for prostate cancer: Results from a statewide urological quality improvement collaborative
Urology. 2021 Apr 29
PMID: 33933504   
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Abstract
OBJECTIVES: To examine the relationship between influential factors and treatment decisions among men with newly diagnosed prostate cancer (PCa). METHODS: We identified men in the Michigan Urological Surgery Improvement Collaborative registry diagnosed with localized PCa between 2018-20 who completed Personal Patient Profile-Prostate (P3P). We analyzed the proportion of active surveillance (AS) between men who stated future bladder, bowel, and sexual problems (termed influential factors) had "a lot of influence" on their treatment decisions versus other responses. We also assessed the relationship between influential factors, confirmatory testing results and choice of AS. RESULTS: A total of 509 men completed P3P. Treatment decisions aligned with influential factors for 88% of men with favorable risk and 49% with unfavorable risk PCa. A higher proportion of men who identified bladder, bowel and sexual concerns as having "a lot of influence" on their treatment decision chose AS, compared with men with other influential factors, although not statistically significant (44% vs 35%, p=0.11). Similar results were also found when men were stratified based on PCa risk groups (favorable risk: 78% vs. 67%; unfavorable risk: 17% vs. 9%, respectively). Despite a small sample size, a higher proportion of men with non-reassuring confirmatory testing selected AS if influential factors had "a lot of influence" compared to "no influence" on their treatment decisions. CONCLUSIONS: Men's concerns for future bladder, bowel, and sexual function problems, as elicited by a decision aid, may help explain treatment selection that differs from traditional clinical recommendation.
Notes
1527-9995 Paudel, Roshan Ferrante, Stephanie Qi, Ji Dunn, Rodney L Berry, Donna L Semerjian, Alice Brede, Christopher M George, Arvin K Lane, Brian R Ginsburg, Kevin B Montie, James E Lane, Giulia I Michigan Urological Surgery Improvement Collaborative Journal Article United States Urology. 2021 Apr 29:S0090-4295(21)00350-2. doi: 10.1016/j.urology.2021.04.020.