FCCC LOGO Faculty Publications
Smith MR
Prothymosin-Alpha - in Search of a Function
Leukemia & Lymphoma. 1995 Jul;18(3-4) :209-214
PMID: ISI:A1995RU51200003   
Back to previous list
Abstract
Prothymosin alpha is an acidic nuclear protein that is expressed at high levels in a wide variety of cell types, Accumulating data correlate prothymosin expression with alterations in the proliferative state of cells. Some data indicates that prothymosin may actually be necessary, if not sufficient, for proliferation, and that prothymosin may function in a c-myc associated pathway. Prothymosin is highly conserved through evolution suggesting a key function, however, that function remains unknown.
Notes
Times Cited: 9 Review RU512 LEUK LYMPHOMA