FCCC LOGO Faculty Publications
Orel SG , Schnall MD , Powell CM , Hochman MG , Solin LJ , Fowble BL , Torosian MH , Rosato EF
Staging of Suspected Breast-Cancer - Effect of Mr-Imaging and Mr-Guided Biopsy
Radiology. 1995 Jul;196(1) :115-122
PMID: ISI:A1995RE30800027   
Back to previous list
PURPOSE: To investigate the effect of contrast material- enhanced magnetic resonance (MR) imaging on staging of breast cancer in patients with mammographically or clinically suspected tumor. MATERIALS AND METHODS: One hundred seventy-six patients underwent breast MR imaging at 1.5 T before excisional biopsy of a suspicious mammographic or palpable abnormality. Diagnostic imaging studies in patients with biopsy-proved or presumed breast carcinoma were reviewed. RESULTS: Sixty-four patients met the study criteria. MR imaging enabled detection of all 57 invasive breast cancers and nine of 15 in situ cancers. In 22 patients (34%), MR imaging depicted one or more cancers not visible at mammography, 13 (20%) of which were unsuspected multifocal or diffuse disease. As a result of the increased sensitivity of MR imaging compared with that of mammography, clinical staging and subsequent treatment were altered in seven patients (11%). CONCLUSION: MR imaging allows detection of mammographically and clinically occult foci of carcinoma in patients with suspected breast cancer.
Times Cited: 119 Article RE308 RADIOLOGY