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Benson AB , Venook AP , Al-Hawary MM , Arain MA , Chen YJ , Ciombor KK , Cohen S , Cooper HS , Deming D , Garrido-Laguna I , Grem JL , Gunn A , Hoffe S , Hubbard J , Hunt S , Kirilcuk N , Krishnamurthi S , Messersmith WA , Meyerhardt J , Miller ED , Mulcahy MF , Nurkin S , Overman MJ , Parikh A , Patel H , Pedersen K , Saltz L , Schneider C , Shibata D , Skibber JM , Sofocleous CT , Stoffel EM , Stotsky-Himelfarb E , Willett CG , Johnson-Chilla A , Gurski LA
NCCN Guidelines Insights: Rectal Cancer, Version 6.2020
J Natl Compr Canc Netw. 2020 Jul;18(7) :806-815
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Abstract
The NCCN Guidelines for Rectal Cancer provide recommendations for the diagnosis, evaluation, treatment, and follow-up of patients with rectal cancer. These NCCN Guidelines Insights summarize the panel discussion behind recent important updates to the guidelines. These updates include clarifying the definition of rectum and differentiating the rectum from the sigmoid colon; the total neoadjuvant therapy approach for localized rectal cancer; and biomarker-targeted therapy for metastatic colorectal cancer, with a focus on new treatment options for patients with BRAF V600E- or HER2 amplification-positive disease.
Notes
Benson, Al B Venook, Alan P Al-Hawary, Mahmoud M Arain, Mustafa A Chen, Yi-Jen Ciombor, Kristen K Cohen, Stacey Cooper, Harry S Deming, Dustin Garrido-Laguna, Ignacio Grem, Jean L Gunn, Andrew Hoffe, Sarah Hubbard, Joleen Hunt, Steven Kirilcuk, Natalie Krishnamurthi, Smitha Messersmith, Wells A Meyerhardt, Jeffrey Miller, Eric D Mulcahy, Mary F Nurkin, Steven Overman, Michael J Parikh, Aparna Patel, Hitendra Pedersen, Katrina Saltz, Leonard Schneider, Charles Shibata, David Skibber, John M Sofocleous, Constantinos T Stoffel, Elena M Stotsky-Himelfarb, Eden Willett, Christopher G Johnson-Chilla, Alyse Gurski, Lisa A eng J Natl Compr Canc Netw. 2020 Jul;18(7):806-815. doi: 10.6004/jnccn.2020.0032.