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Kappes DJ , Alarcon B , Regueiro JR
T-Lymphocyte Receptor Deficiencies
Current Opinion in Immunology. 1995 Aug;7(4) :441-447
PMID: ISI:A1995RV08100003   
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Abstract
Signalling through the TCR is mediated by the cytoplasmic tails of the CD3 complex. Deficiencies in the expression of different CD3 components have lead to dramatic, yet dissimilar, effects on T-cell development and to selective deficits in peripheral T-cell subsets. Recent studies of human patients and animal models with CD3 deficiencies are providing insights into the redundant and unique roles of these molecules.
Notes
Times Cited: 22 Review RV081 CURR OPIN IMMUNOL