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Yen TJ , Schaar BT
Kinetochore function: Molecular motors, switches and gates
Current Opinion in Cell Biology. 1996 Jun;8(3) :381-388
AbstractKinetochores are essential for accurate chromosome segregation. Recent studies reveal that vertebrate kinetochores are sophisticated propulsion systems composed of not only force generators but also 'navigation' and 'fail-safe' mechanisms. Advances toward the understanding of the biochemical composition and activities of the components of the kinetochore have come from the molecular characterization of key proteins of the kinetochore complex.
NotesTimes Cited: 16 English Article UM873 CURR OPIN CELL BIOL