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Ma GX , Lee MM , Tan Y , Hanlon AL , Feng Z , Shireman TI , Rhee J , Wei Z , Wong F , Koh HS , Kim C , York W
Efficacy of a community-based participatory and multilevel intervention to enhance hepatitis B virus screening and vaccination in underserved Korean Americans
Cancer. 2018 Mar 1;124(5) :973-982
PMID: 29131316    PMCID: PMC5821582    URL: https://www.ncbi.nlm.nih.gov/pubmed/29131316
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Abstract
BACKGROUND: The primary objective of the current study was to evaluate the efficacy of a community-based participatory intervention program in improving hepatitis B virus (HBV) screening and vaccination among Korean Americans who were not previously screened. METHODS: A cluster randomized trial involving 32 Korean church-based community organizations (1834 participants) was conducted. Sixteen churches were randomly assigned to an HBV screening and vaccination multicomponent intervention condition (972 participants) and 16 were assigned to a general cancer education control condition (862 participants). The main components of the intervention program included interactive group education; patient navigation; and the engagement of health care providers, church leadership, and church members in the medical field. The application of community-based participatory research principles was monitored and evaluated. HBV screening and vaccination rates (self-reported and medical record verification) were assessed at 6-month and 12-month follow-ups, respectively. RESULTS: The results of the current study demonstrated significant efficacy in the HBV screening rate (92.5% in the intervention group vs 5.5% in the control group), 3-series HBV vaccination completion rate (84% in the intervention group vs 17.6% in the control group), and overall screening and vaccination compliance rate (87% in the intervention group vs 3.8% in the control group). Participants in the intervention group were significantly more likely to receive HBV screening (92.5%) compared with those in the control group (5.5%). In multivariate mixed-effect logistic regression analysis, the odds ratio for an intervention effect on HBV screening was 512.3 after adjusting for cluster effect and other demographic variables. With regard to vaccination rates, of the 332 participants who were screened with no immunity in the intervention group, 308 (92.8%) received at least 1 HBV vaccination, 300 (90.4%) received at least 2 shots, and 279 participants (84%) received all 3 shots. CONCLUSIONS: A combination of community-based participatory research and a multilevel approach may produce the most optimal results and be essential in producing a considerable effect for enhancing HBV screening and vaccination, particularly for Korean American populations with limited language proficiency and insurance coverage. Cancer 2017. (c) 2017 American Cancer Society.
Notes
1097-0142 Ma, Grace X ORCID: http://orcid.org/0000-0002-3619-0550 Lee, Minsun M Tan, Yin Hanlon, Alexandra L Feng, Ziding Shireman, Theresa I Rhee, Joanne Wei, Zhengyu Wong, Frank Koh, Han Seung Kim, Charles York, Whitney R24 MD002756/MD/NIMHD NIH HHS/United States U54 CA153513/CA/NCI NIH HHS/United States Journal Article United States Cancer. 2017 Nov 13. doi: 10.1002/cncr.31134.