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Loll PJ , Garavito RM , Carrell CJ , Carrell HL
1-(4-Iodobenzoyl)-5-methoxy-2-methyl-3-indoleacetic acid, an iodinated indomethacin analog
Acta Crystallographica Section C-Crystal Structure Communications. 1996 Feb 15;52 :455-457
PMID: ISI:A1996TY31700072   
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The crystal structure of 1-(4-iodobenzoyl)-5-methoxy-2-methyl- 3-indoleacetic acid, C19H16INO4, an analog of indomethacin, is reported. Bond distances and angles in the title compound closely resemble those reported for indomethacin and reflect the presence of steric strain at the site of the linkage between the 4-iodobenzoyl group and the indole moiety. The orientation of the 4-iodobenzoyl group with respect to the indole ring is not the same in the title compound as it is in indomethacin; the two structures are related by a rotation of 186 degrees about the C2-N1-C10-C11 torsion angle.
Times Cited: 3 English Article 2 TY317 ACTA CRYSTALLOGR C-CRYST STR