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Langer CJ , Hageboutros A , Kloth DD , Roby D , Shaer AH
Acute encephalopathy attributed to 5-FU
Pharmacotherapy. 1996 Mar-Apr;16(2) :311-313
AbstractAcute encephalopathy attributable to 5-fluorouracil (5-FU) is rare. A patient experienced this reaction associated with a continuous 5-FU infusion. The etiology of the event remains uncertain, but it is generally reversible and does not preclude retreatment with 5-FU at reduced dosages. Steroids and thiamine may expedite neurologic recovery.
NotesTimes Cited: 4 English Article UA856 PHARMACOTHERAPY