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Kheterpal S , Shileds JA , Shields CL , DePotter P , Ehya H , Eng KY
Choroidal melanoma in an African-American albino
American Journal of Ophthalmology. 1996 Dec;122(6) :901-903
PMID: ISI:A1996VW75800025   
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PURPOSE: To report the rare occurrence of choroidal melanoma in an African-American albino. METHODS: A 68 year-old African American man with oculocutaneous albinism developed an amelanotic choroidal mass in: his left eye. A transvitreal fine needle aspiration biopsy was performed to confirm the diagnosis, and the patient was treated with iodine 125 plaque radiotherapy. RESULTS: The cytology of the needle biopsy showed spindle cells with nuclear atypia and prominent nucleoli. The cells showed positive immuno-reactivity for HMB-45, supporting the diagnosis of choroidal melanoma. CONCLUSION: To our knowledge, this is the first reported case of a choroidal melanoma occurring in an African American albino.
Times Cited: 0 English Article VW758 AMER J OPHTHALMOL