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Chambers SK , Foley E , Clutton S , McDowall R , Occhipinti S , Berry M , Stockler MR , Lepore SJ , Frydenberg M , Gardiner RA , Davis ID , Smith DP
The role of mindfulness in distress and quality of life for men with advanced prostate cancer
Qual Life Res. 2016 Dec;25(12) :3027-3035
PMID: 27315118 PMCID: PMC5102949 URL: http://www.ncbi.nlm.nih.gov/pubmed/27315118
AbstractOBJECTIVE: To examine the extent to which mindfulness skills influence psychological distress and health-related quality of life (HRQOL) in men with metastatic or castration-resistant biochemical progression of prostate cancer. PATIENTS AND METHODS: A cross-sectional survey of 190 men (46 % response; mean age 71 years, SD = 8.7, range 40-91 years) with advanced prostate cancer, assessed psychological and cancer-specific distress, HRQOL. Mindfulness skills were assessed as potential predictors of adjustment outcomes. RESULTS: Overall, 39 % of men reported high psychological distress. One third had accessed psychological support previously although only 10 % were under current psychological care. One quarter had accessed a prostate cancer support group in the past six months. Higher HRQOL and lower cancer-specific and global psychological distress were related to non-judging of inner experience (p < 0.001). Higher HRQOL and lower psychological distress were related to acting with awareness (p < 0.001). Lower distress was also related to higher non-reactivity to inner experience and a lower level of observing (p < 0.05). CONCLUSIONS: Men with advanced prostate cancer are at risk of poor psychological outcomes. Psychological flexibility may be a promising target for interventions to improve adjustment outcomes in this patient group. CLINICAL TRIAL REGISTRY: Trial Registration: ACTRN12612000306819.
NotesChambers, Suzanne K Foley, Elizabeth Clutton, Samantha McDowall, Robert Occhipinti, Stefano Berry, Martin Stockler, Martin R Lepore, Stephen J Frydenberg, Mark Gardiner, Robert A Davis, Ian D Smith, David P Qual Life Res. 2016 Jun 17.