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Gayle MA , Slack JL , Bonnert TP , Renshaw BR , Sonoda G , Taguchi T , Testa JR , Dower SK , Sims JE
Cloning of a putative ligand for the T1/ST2 receptor
Journal of Biological Chemistry. 1996 Mar 8;271(10) :5784-5789
AbstractT1/ST2 is a receptor-like molecule homologous to the type I interleukin-1 receptor. Despite this sequence similarity, me have been unable to demonstrate binding of T1/ST2 to any of the three interleukin-1 species. In searching for a ligand for T1/ST2, we have cloned a cell surface protein to which it binds. This protein is unable to initiate signal transduction by the T1/ST2 receptor in several in vitro assays.
NotesTimes Cited: 33 English Article TZ286 J BIOL CHEM