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Impact of baseline patient-reported dysphagia on acute gastrostomy placement in patients with head and neck squamous cell carcinoma undergoing definitive radiation
Head Neck. 2016 Apr;38 Suppl 1 :E1318-24
PMID: 26332292 URL: http://www.ncbi.nlm.nih.gov/pubmed/26332292
AbstractBACKGROUND: Dysphagia-related symptoms in patients with head and neck cancer are common before treatment. We hypothesized greater self-reported baseline dysphagia would predict gastrostomy placement during primary radiation. METHODS: Swallowing-specific/general surveys (SwalQOL/EuroQOL) collected prospectively before definitive radiation were analyzed for associations with gastrostomy placement. Prophylactic gastrostomy was recommended at the discretion of a multidisciplinary team blinded to the surveys. RESULTS: Of 84 patients in the cohort, 42 patients (50%) received feeding tubes. Eleven patients (13%) who underwent prophylactic feeding tube placement reported the greatest pretreatment dysphagia, whereas those who avoided gastrostomies reported the least. Prophylactic gastrostomy was more strongly associated with patient-reported measures than other clinical criteria. Controlling for stage IV, T3 to T4 classification, smoking, chemotherapy, and pretreatment weight loss, baseline dysphagia remained an independent predictor of feeding tube placement (odds ratio [OR] = 0.12; 95% confidence interval [CI] = 0.05-0.55; p = .01). Patients without gastrostomies during treatment avoided persistent gastrostomy dependence. CONCLUSION: Baseline dysphagia-related symptoms before radiation are independent predictors of gastrostomy placement. (c) 2015 Wiley Periodicals, Inc. Head Neck 38: E1318-E1324, 2016.
NotesLango, Miriam N Galloway, Thomas J Mehra, Ranee Ebersole, Barbara Liu, Jeffrey Chang-Jen Moran, Kathleen Ridge, John A eng 2015/09/04 06:00 Head Neck. 2016 Apr;38 Suppl 1:E1318-24. doi: 10.1002/hed.24220. Epub 2015 Aug 31.