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Pfister DG , Spencer S , Brizel DM , Burtness B , Busse PM , Caudell JJ , Cmelak AJ , Colevas AD , Dunphy F , Eisele DW , Foote RL , Gilbert J , Gillison ML , Haddad RI , Haughey BH , Hicks WL Jr , Hitchcock YJ , Jimeno A , Kies MS , Lydiatt WM , Maghami E , McCaffrey T , Mell LK , Mittal BB , Pinto HA , Ridge JA , Rodriguez CP , Samant S , Shah JP , Weber RS , Wolf GT , Worden F , Yom SS , McMillian N , Hughes M
Head and Neck Cancers, Version 1.2015
J Natl Compr Canc Netw. 2015 Jul;13(7) :847-56
PMID: 26150579   
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These NCCN Guidelines Insights focus on recent updates to the 2015 NCCN Guidelines for Head and Neck (H&N) Cancers. These Insights describe the different types of particle therapy that may be used to treat H&N cancers, in contrast to traditional radiation therapy (RT) with photons (x-ray). Research is ongoing regarding the different types of particle therapy, including protons and carbon ions, with the goals of reducing the long-term side effects from RT and improving the therapeutic index. For the 2015 update, the NCCN H&N Cancers Panel agreed to delete recommendations for neutron therapy for salivary gland cancers, because of its limited availability, which has decreased over the past 2 decades; the small number of patients in the United States who currently receive this treatment; and concerns that the toxicity of neutron therapy may offset potential disease control advantages.
Pfister, David G Spencer, Sharon Brizel, David M Burtness, Barbara Busse, Paul M Caudell, Jimmy J Cmelak, Anthony J Colevas, A Dimitrios Dunphy, Frank Eisele, David W Foote, Robert L Gilbert, Jill Gillison, Maura L Haddad, Robert I Haughey, Bruce H Hicks, Wesley L Jr Hitchcock, Ying J Jimeno, Antonio Kies, Merrill S Lydiatt, William M Maghami, Ellie McCaffrey, Thomas Mell, Loren K Mittal, Bharat B Pinto, Harlan A Ridge, John A Rodriguez, Cristina P Samant, Sandeep Shah, Jatin P Weber, Randal S Wolf, Gregory T Worden, Frank Yom, Sue S McMillian, Nicole Hughes, Miranda United States J Natl Compr Canc Netw. 2015 Jul;13(7):847-56.