This is an archive of papers published by the staff and faculty of Fox Chase Cancer Center. For questions about content, please contact Talbot Research Library
Last updated on
Manne S , Kashy D , Albrecht T , Wong YN , Flamm AL , Benson AB 3rd , Miller SM , Fleisher L , Buzaglo J , Roach N , Katz M , Ross E , Collins M , Poole D , Raivitch S , Miller DM , Kinzy TG , Liu T , Meropol NJ
Knowledge, attitudes, and self-efficacy as predictors of preparedness for oncology clinical trials: a mediational model
Med Decis Making. 2014 May;34(4) :454-63
PMID: 24246567 PMCID: PMC3991731 URL: https://www.ncbi.nlm.nih.gov/pubmed/24246567
AbstractOBJECTIVE: This study used the Ottawa Decision Support Framework to evaluate a model examining associations between clinical trial knowledge, attitudinal barriers to participating in clinical trials, clinical trial self-efficacy, and clinical trial preparedness among 1256 cancer patients seen for their first outpatient consultation at a cancer center. As an exploratory aim, moderator effects for gender, race/ethnicity, education, and metastatic status on associations in the model were evaluated. METHODS: . Patients completed measures of cancer clinical trial knowledge, attitudinal barriers, self-efficacy, and preparedness. Structural equation modeling (SEM) was conducted to evaluate whether self-efficacy mediated the association between knowledge and barriers with preparedness. RESULTS: . The SEM explained 26% of the variance in cancer clinical trial preparedness. Self-efficacy mediated the associations between attitudinal barriers and preparedness, but self-efficacy did not mediate the knowledge-preparedness relationship. CONCLUSIONS: . Findings partially support the Ottawa Decision Support Framework and suggest that assessing patients' level of self-efficacy may be just as important as evaluating their knowledge and attitudes about cancer clinical trials.
NotesManne, Sharon Kashy, Deborah Albrecht, Terrance Wong, Yu-Ning Flamm, Anne Lederman Benson, Al B 3rd Miller, Suzanne M Fleisher, Linda Buzaglo, Joanne Roach, Nancy Katz, Michael Ross, Eric Collins, Michael Poole, David Raivitch, Stephanie Miller, Dawn M Kinzy, Tyler G Liu, Tasnuva Meropol, Neal J eng R01 CA127655/CA/NCI NIH HHS/ Research Support, N.I.H., Extramural Med Decis Making. 2014 May;34(4):454-63. doi: 10.1177/0272989X13511704. Epub 2013 Nov 18.