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Ray M , Farma JM , Hsu C
Translational Research in Melanoma
Surgical Oncology Clinics of North America. 2013 Oct;22(4) :785-+
AbstractRecent breakthroughs in the fundamental understanding of the cellular and molecular basis of melanoma have culminated in new therapies with unquestionable efficacy. Immunotherapy and targeted therapy strategies have completely transformed the contemporary management of advanced melanoma. The translational research behind these developments is discussed, with an emphasis on immune checkpoint blockade and inhibition of the mitogen-activated protein kinase signaling pathway.
NotesRay, Madhury Farma, Jeffrey M. Hsu, Cary