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Nabors LB , Ammirati M , Bierman PJ , Brem H , Butowski N , Chamberlain MC , DeAngelis LM , Fenstermaker RA , Friedman A , Gilbert MR , Hesser D , Holdhoff M , Junck L , Lawson R , Loeffler JS , Maor MH , Moots PL , Morrison T , Mrugala MM , Newton HB , Portnow J , Raizer JJ , Recht L , Shrieve DC , Sills AK , Tran D , Tran N , Vrionis FD , Wen PY , McMillian N , Ho M
Central Nervous System Cancers Clinical Practice Guidelines in Oncology
Journal of the National Comprehensive Cancer Network. 2013 Sep;11(9) :1114-1151
PMID: WOS:000324310800008   
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Abstract
Primary and metastatic tumors of the central nervous system are a heterogeneous group of neoplasms with varied outcomes and management strategies. Recently, improved survival observed in 2 randomized clinical trials established combined chemotherapy and radiation as the new standard for treating patients with pure or mixed anaplastic oligodendroglioma harboring the 1p/19q codeletion. For metastatic disease, increasing evidence supports the efficacy of stereotactic radiosurgery in treating patients with multiple metastatic lesions but low overall tumor volume. These guidelines provide recommendations on the diagnosis and management of this group of diseases based on clinical evidence and panel consensus. This version includes expert advice on the management of low-grade infiltrative astrocytomas, oligodendrogliomas, anaplastic gliomas, glioblastomas, medulloblastomas, supratentorial primitive neuroectodermal tumors, and brain metastases. The full online version, available at NCCN. org, contains recommendations on additional subtypes.
Notes
Nabors, Louis Burt Ammirati, Mario Bierman, Philip J. Brem, Henry Butowski, Nicholas Chamberlain, Marc C. DeAngelis, Lisa M. Fenstermaker, Robert A. Friedman, Allan Gilbert, Mark R. Hesser, Deneen Holdhoff, Matthias Junck, Larry Lawson, Ronald Loeffler, Jay S. Maor, Moshe H. Moots, Paul L. Morrison, Tara Mrugala, Maciej M. Newton, Herbert B. Portnow, Jana Raizer, Jeffrey J. Recht, Lawrence Shrieve, Dennis C. Sills, Allen K. Tran, David Tran, Nam Vrionis, Frank D. Wen, Patrick Y. McMillian, Nicole Ho, Maria