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Bleicher RJ
Ductal carcinoma in situ
Surg Clin North Am. 2013 Apr;93(2) :393-410
PMID: 23464692   
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Abstract
Management of ductal carcinoma in situ (DCIS) has evolved from radical surgery to the option of a more minimally invasive approach. Data show that breast conservation surgery performed with administration of radiotherapy, like mastectomy, is feasible and safe. Because efforts to find a safe group for elimination of radiotherapy have resulted in data that conflict, radiotherapy still remains standard of care as a part of breast conservation for DCIS. Tamoxifen has also shown a significant recurrence benefit and has become standard in the treatment of receptor-positive disease. Investigation of other agents, such as anastrazole and trastuzumab, are ongoing.
Notes
Bleicher, Richard J United States The Surgical clinics of North America Surg Clin North Am. 2013 Apr;93(2):393-410. doi: 10.1016/j.suc.2012.12.001. Epub 2013 Jan 29.