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Malaviya L , Shields CL , Turaka K , Ehya H , Shields JA
Choroidal metastasis from hepatocellular carcinoma, diagnosed by fine needle aspiration biopsy and treated by iodine-125 brachytherapy
Graefes Archive for Clinical and Experimental Ophthalmology. 2011 Jul;249(7) :1095-1098
PMID: ISI:000292163400019   
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Abstract
To report a rare case of choroidal metastasis from hepatocellular carcinoma. A 63-year-old man with known hepatocellular carcinoma (HCC) and treated clavicular metastasis noted reduced visual acuity in the right eye. He was found to have an amelanotic choroidal tumor measuring 18 x 14 x 9.3 mm and with retinal detachment. Fine needle aspiration biopsy confirmed metastatic HCC. The choroidal metastasis was treated with 5 days of iodine-125 plaque brachytherapy (3500 cGy to apex). Tumor regression to 2.6 mm thickness with resolution of retinal detachment and preservation of visual acuity at 20/40 at the 4-month follow-up was documented. HCC metastasis to the choroid can be treated with focal plaque brachytherapy, with preservation of vision and quality of life.
Notes
Malaviya, Lalkrushna Shields, Carol L. Turaka, Kiran Ehya, Hormoz Shields, Jerry A. Retina Research Foundation of the Retina Society in Cape Town, South Africa ; Paul Kayser International Award of Merit in Retina Research, Houston, TX, USA ; LuEsther Mertz Retina Research Foundation, New York, NY, USA ; Eye Tumor Research Foundation, Philadelphia, PA, USA Support provided by the Retina Research Foundation of the Retina Society in Cape Town, South Africa (CLS); the Paul Kayser International Award of Merit in Retina Research, Houston, TX, USA (JAS); a donation from Michael, Bruce, and Ellen Ratner, New York, NY, USA (JAS, CLS); Mellon Charitable Giving from the Martha W. Rogers Charitable Trust, Philadelphia, PA, USA (CLS); the LuEsther Mertz Retina Research Foundation, New York, NY, USA (CLS); and the Eye Tumor Research Foundation, Philadelphia, PA, USA (CLS, JAS). 9 Springer; 233 spring st, new york, ny 10013 usa 784ng