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Bui MM , Draper NL , Dessureault S , Nasir NA , Cooper H , Nasir A , Coppola D
Colonic Angiolymphoid Hyperplasia With Eosinophilia Masquerading as Malignancy: A Case Report and Review of the Literature
Clinical Colorectal Cancer. 2010 Jul;9(3) :179-182
PMID: ISI:000280072300008   
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Angiolymphoid hyperplasia with eosinophilia (AHE) of the colon is a rare entity. Since 1997, to our knowledge only 2 similar cases have been documented in the literature. Here, we report a third case that presented as a transverse colonic mass mimicking cancer both clinically and radiologically. Microscopically classic morphologic criteria of this entity were observed, which consisted of both a vascular proliferation and an inflammatory component rich in eosinophils without any malignant features. Whether AHE is a reactive process or a neoplastic process (either a benign vascular neoplasm or a T-cell lymphoproliferative disorder) is still under debate. However, it is important to recognize this entity as a cause of colonic mass to avoid a misdiagnosis of malignancy.
Bui, Marilyn M. Draper, Nicole L. Dessureault, Sophie Nasir, Nelly A. Cooper, Harry Nasir, Aejaz Coppola, Domenico 19 Cig media group, lp; 3500 maple avenue, ste 750, dallas, tx 75219-3931 usa 627vs