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Lai JS , Butt Z , Wagner L , Sweet JJ , Beaumont JL , Vardy J , Jacobsen PB , Shapiro PJ , Jacobs SR , Cella D
Evaluating the dimensionality of perceived cognitive function
J Pain Symptom Manage. 2009 Jun;37(6) :982-95
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Abstract
Decrements in cognitive function are common in cancer patients and other clinical populations. As direct neuropsychological testing is often not feasible or affordable, there is potential utility in screening for deficits that may warrant a more comprehensive neuropsychological assessment. Furthermore, some evidence suggests that perceived cognitive function (PCF) is independently associated with structural and functional changes on neuroimagery, and may precede more overt deficits. To appropriately measure PCF, one must understand its components and the underlying dimensional structure. The purpose of this study was to examine the dimensionality of PCF in people with cancer. The sample included 393 cancer patients from four clinical trials who completed a questionnaire consisting of the prioritized areas of concerns identified by patients and clinicians: self-reported mental acuity, concentration, memory, verbal fluency, and functional interference. Each area contained both negatively worded (i.e., deficit) and positively worded (i.e., capability) items. Data were analyzed by using Cronbach's alpha, item-total correlations, one-factor confirmatory factor analysis, and a bi-factor analysis model. Results indicated that perceived cognitive problem items are distinct from cognitive capability items, supporting a two-factor structure of PCF. Scoring of PCF based on these two factors should lead to improved assessment of PCF for people with cancer.
Notes
Lai, Jin-Shei Butt, Zeeshan Wagner, Lynne Sweet, Jerry J Beaumont, Jennifer L Vardy, Janette Jacobsen, Paul B Shapiro, Pamela J Jacobs, Sheri R Cella, David CA125671/CA/NCI NIH HHS/United States CA60068/CA/NCI NIH HHS/United States U01 AR 052177-01/AR/NIAMS NIH HHS/United States Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S. United States Journal of pain and symptom management J Pain Symptom Manage. 2009 Jun;37(6):982-95.