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Rothman J , Greenberg RE , Jaffe WI
Nonseminomatous germ cell tumor of the testis 9 years after a germ cell tumor of the pineal gland: case report and review of the literature
Canadian Journal of Urology. 2008 Jun;15(3) :4122-4124
PMID: ISI:000261638800019   
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Extragonadal germ cell tumors are extremely rare and account for only 3%-5% of all germ cell tumors. These tumors are rarely associated with metachronous primary testicular germ cell tumors. We report the fourth case of a primary germ cell tumor occurring after the treatment of a primary CNS germ cell tumor in a 27-year-old male with embryonal cell carcinoma of the testicle 9 years after the treatment of a germ cell tumor of the pineal gland. This represents the first case of a non-seminomatous germ cell tumor of the testicle after a CNS germ cell tumor. This case illustrates the importance of long term follow-up and self-examination in patients with extragonadal germ cell tumors.
Rothman, Jason Greenberg, Richard E. Jaffe, William I. 15 CANADIAN J UROLOGY; 2330 WARD ST, STE 604, ST LAURENT, QUEBEC H4M 2V6, CANADA 382XN