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Palamar M , Shields CL , Ghassemi F , Ehya H , Shields JA
Choroidal plasmacytoma in a patient with multiple myeloma. Diagnosis by fine-needle aspiration biopsy
Graefes Archive for Clinical and Experimental Ophthalmology. 2008 Aug;246(8) :1195-1197
PMID: ISI:000257204900016   
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Abstract
Background To report a case of a secondary plasmacytoma of the choroid. Methods Interventional case report with cytopathologic correlation. Results A 61-year-old male with a breast nodule and a 2-year history of multiple myeloma developed blurred vision and was found to have three confluent, ill-defined areas of choroidal thickening in the left eye. Cytopathology and immunohistochemistry of a transocular fine-needle aspiration biopsy of the largest lesion revealed atypical plasma cells diagnostic of plasmacytoma. Following external beam radiotherapy the choroidal tumors resolved completely. Conclusion Secondary plasmacytoma, despite its rarity, should be included in the differential diagnosis of amelanotic choroidal tumors, particularly in patients with multiple myeloma. Radiotherapy is an effective treatment.
Notes
ISI Document Delivery No.: 320AA Times Cited: 0 Cited Reference Count: 8 Cited References: ADKINS JW, 1997, INT OPHTHALMOL, V20, P339 GOLDSTEIN DA, 2005, CORNEA, V24, P757 HONAVAR SG, 2001, AM J OPHTHALMOL, V131, P277 MORGAN AE, 2003, RETINA-J RET VIT DIS, V23, P867 SHAKIN EP, 1988, ARCH OPHTHALMOL-CHIC, V106, P524 SHIELDS CL, 2007, CORNEA, V26, P759 SHIELDS JA, 2006, INTRAOCULAR TUMORS T, P504 THOUMAZET F, 2006, CAN J OPHTHALMOL, V41, P733 Palamar, Melis Shields, Carol L. Ghassemi, Fariba Ehya, Hormoz Shields, Jerry A. SPRINGER; 233 SPRING ST, NEW YORK, NY 10013 USA