This is an archive of papers published by the staff and faculty of Fox Chase Cancer Center. For questions about content, please contact Talbot Research Library
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CD4 and CD8: Hogging All the Lck
Immunity. 2007 Nov 26;27(5) :691-693
AbstractSpecificity of T cell receptors (TCRs) to major histocompatibility complex (MHC) might be intrinsic or imposed by thymic selection. Van Laethem et al. (2007) propose that the sequestration of the kinase Lck by coreceptors prevents the selection of non-MHC-reactive TCRs.
NotesImmunity. 2007 Nov 26;27(5):691-693.