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Malone MD , Barber L , Comerota AJ
Clinical applications of thrombolytic therapy for arterial and graft occlusion
Surgical Clinics of North America. 1998 Aug;78(4) :647-+
PMID: ISI:000075519700010   
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Catheter-directed thrombolytic therapy has become an important part of the treatment of patients with acute arterial and graft occlusion. The underlying principle is the activation of plasminogen-bound fibrin within the thrombus. Guidewire passage has been found to be a good predictor of success of catheter- directed thrombolysis. The underlying disease process leading to thrombosis should be accurately identified and promptly corrected to reduce the probability of recurrent occlusion. Patient selection, basic technical considerations, overall results, and an overview of prospective randomized studies are reviewed in this summary of catheter-directed thrombolytic therapy.
Times Cited: 4 English Article 112XH SURG CLIN N AMER