This is an archive of papers published by the staff and faculty of Fox Chase Cancer Center. For questions about content, please contact Talbot Research Library
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Battineni ML , Galetta SL , Oh J , Lango M , Brooks JJ , Schuster SJ , Loevner LA
Idiopathic hypereosinophilic syndrome with skull base involvement
American Journal of Neuroradiology. 2007 May;28(5) :971-973
AbstractIdiopathic hypereosinophilic syndrome (HES) is a heterogeneous disorder characterized by prolonged eosinophilia without an identifiable cause, ultimately resulting in organ dysfunction. Three major types of neurologic involvement have been well defined in HES; however, to our knowledge, inflammatory pseudotumor (IPT) in association with HES has not been reported. We present a case of IPT of the skull base in a patient with HES that suggests that HES may result in an exaggerated immunologic or inflammatory response leading to the formation of IPT.