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Shields CL , Chong WH , Ehya H , Shields JA
Sequential Bilateral Solitary Extramedullary Plasmacytoma of the Ciliary Body
Cornea. 2007 Jul;26(6) :759-761
AbstractPURPOSE:: To report bilateral plasmacytoma of the ciliary body in a healthy patient. METHODS:: Clinicopathologic report. RESULTS:: A 55-year-old woman with iritis developed an iridociliary mass in the left eye. Systemic evaluation was normal. Fine-needle aspiration (FNAB) of the mass revealed atypical, binucleate plasmacytoid cells with positive leukocyte common antigen staining, suggestive of plasmacytoma. The tumor was treated with 4000 cGy by using custom-designed plaque radiotherapy. The tumor completely resolved. Two years later, a similar iridociliary mass was noted in the right eye, and FNAB confirmed plasmacytoma. Plaque radiotherapy of 4000 cGy was delivered. At the 3-year follow-up, there has been no local recurrence or evidence of systemic multiple myeloma or monoclonal gammopathy. CONCLUSIONS:: Extramedullary plasmacytoma can involve the uvea and rarely manifest multiplicity. Long-term monitoring for systemic plasma cell dyscrasia is warranted.