FCCC LOGO Faculty Publications

Cancer Signaling and Epigenetics (selected publications)


2021
Wang H, Wei W, Zhang JP, Song Z, Li Y, Xiao W, Liu Y, Zeng MS, Petrus MN, Thomas CJ, Kadin ME, Nakagawa M, Waldmann TA, Yang Y. A novel model of alternative NF-κB pathway activation in anaplastic large cell lymphoma. Leukemia. 2021 Jul;35(7):1976-1989.
Makhov P, Uzzo RG, Tulin AV, Kolenko VM. Histone-dependent PARP-1 inhibitors: A novel therapeutic modality for the treatment of prostate and renal cancers. Urol Oncol. 2021 jun;39(6):312-315.
Börcsök J, Sztupinszki Z, Bekele R, Gao SP, Diossy M, Samant AS, Dillon KM, Tisza V, Spisák S, Rusz O, Csabai I, Pappot H, Frazier ZJ, Konieczkowski DJ, Liu D, Vasani N, Rodrigues JA, Solit DB, Hoffman-Censits JH, Plimack ER, Rosenberg JE, Lazaro JB, Taplin ME, Iyer G, Brunak S, Lozsa R, Van Allen EM, Szüts D, Mouw KW, Szallasi Z. Identification of a synthetic lethal relationship between nucleotide excision repair (NER) deficiency and irofulven sensitivity in urothelial cancer. Clin Cancer Res. 2021 Apr;27(7):2011-2022. PubMed Central PMCID: PMC8026514.
Zhao Z, Fowle H, Valentine H, Liu Z, Tan Y, Pei J, Badal S, Testa JR, Graña X. Immortalization of human primary prostate epithelial cells via CRISPR inactivation of the CDKN2A locus and expression of telomerase. Prostate Cancer Prostatic Dis. 2021 Mar;24(1):233-243. PubMed Central PMCID: PMC7917161.
Bilusic M, Girardi D, Zhou Y, Jung K, Pei J, Slifker M, Chen Q, Meerzaman D, Alpaugh K, Young D, Flieder D, Gray P, Plimack E. Molecular Profiling of Exceptional Responders to Cancer Therapy. Oncologist. 2021 Mar;26(3):186-195. PubMed Central PMCID: PMC7930427.
McGillivray E, Farma J, Savage M, Hall MJ, Luo B, Jain R. Pathologic Complete Response in Patient With ATM Mutation After Neoadjuvant FOLFOXIRI Plus Panitumumab Therapy for Locally Advanced Colon Cancer: A Case Report. Clin Colorectal Cancer. 2021 jun;20(2):e96-e99.
Uribe-Alvarez C, Guerrero-Rodriguez SL, Rhodes J, Cannon A, Chernoff J, Araiza-Olivera D. Targeting effector pathways in RAC1(P29S)-driven malignant melanoma. Small GTPases. 2021 Jul;12(4):273-281. PubMed Central PMCID: PMC8205048.
Liu L, Chandrashekar P, Zeng B, Sanderford MD, Kumar S, Gibson G. TreeMap: a structured approach to fine mapping of eQTL variants. Bioinformatics. 2021 May 23;37(8):1125-1134. PubMed Central PMCID: PMC8150140.
Santerre M, Arjona SP, Allen CN, Shcherbik N, Sawaya BE. Why do SARS-CoV-2 NSPs rush to the ER?. J Neurol. 2021 Jun;268(6):2013-2022. PubMed Central PMCID: PMC7461160.
2020
Benton D, Chernoff J. A New Rho(d) Map to Diffuse Gastric Cancer. Cancer Discov. 2020 Feb;10(2):182-184. PubMed Central PMCID: PMC7079203.
Johnson C, Drummer Iv C, Shan H, Shao Y, Sun Y, Lu Y, Saaoud F, Xu K, Nanayakkara G, Fang P, Bagi Z, Jiang X, Choi ET, Wang H, Yang X. A Novel Subset of CD95(+) Pro-Inflammatory Macrophages Overcome miR155 Deficiency and May Serve as a Switch From Metabolically Healthy Obesity to Metabolically Unhealthy Obesity. Front Immunol. 2020;11:619951. PubMed Central PMCID: PMC7817616.
Kumar S. A Report by the Editor-in-Chief for Molecular Biology and Evolution (MBE), Volume 35. Mol Biol Evol. 2020 Jan 1;37(1):300.
Kumar S. A Report by the Editor-in-Chief for Molecular Biology and Evolution (MBE), Volume 36. Mol Biol Evol. 2020 Dec 16;37(12):3699-3700. PubMed Central PMCID: PMC7743802.
Barbe MF, Loomis R, Lepkowsky AM, Forman S, Zhao H, Gordon J. A longitudinal characterization of sex-specific somatosensory and spatial memory deficits in HIV Tg26 heterozygous mice. PLoS One. 2020;15(12):e0244725. PubMed Central PMCID: PMC7775086.
Miura S, Tamura K, Tao Q, Huuki LA, Kosakovsky Pond SL, Priest J, Deng J, Kumar S. A new method for inferring timetrees from temporally sampled molecular sequences. PLoS Comput Biol. 2020 Jan;16(1):e1007046. PubMed Central PMCID: PMC7018096.
Basappa J, Citir M, Zhang Q, Wang HY, Liu X, Melnikov O, Yahya H, Stein F, Muller R, Traynor-Kaplan A, Schultz C, Wasik MA, Ptasznik A. ACLY is the novel signaling target of PIP2/PIP3 and Lyn in acute myeloid leukemia. Heliyon. 2020 May;6(5):e03910. PubMed Central PMCID: PMC7218026.
Huang X, Liu L, Song Y, Gao L, Zhao M, Bao H, Qin X, Wu Y, Wu Q, Bi C, Yue A, Fang C, Ma H, Cui Y, Tang G, Li P, Zhang Y, Li J, Wang B, Xu X, Wang H, Parati G, Spence JD, Wang X, Huo Y, Chen G, Cheng X. Achieving blood pressure control targets in hypertensive patients of rural China - a pilot randomized trial. Trials. 2020 Jun 11;21(1):515. PubMed Central PMCID: PMC7291427.
Duggan M, Torkzaban B, Ahooyi TM, Khalili K, Gordon J. Age-related neurodegenerative diseases. J Cell Physiol. 2020 Apr;235(4):3131-3141. PubMed Central PMCID: PMC7029396.
Alrafas HR, Busbee PB, Chitrala KN, Nagarkatti M, Nagarkatti P. Alterations in the Gut Microbiome and Suppression of Histone Deacetylases by Resveratrol Are Associated with Attenuation of Colonic Inflammation and Protection Against Colorectal Cancer. J Clin Med. 2020 Jun 9;9(6). PubMed Central PMCID: PMC7355848.
Kumar S, Chmura S, Robinson C, Lin SH, Gadgeel SM, Donington J, Feliciano J, Stinchcombe TE, Werner-Wasik M, Edelman MJ, Moghanaki D. Alternative Multidisciplinary Management Options for Locally Advanced NSCLC During the Coronavirus Disease 2019 Global Pandemic. J Thorac Oncol. 2020 Jul;15(7):1137-1146. PubMed Central PMCID: PMC7194660.
Martini JF, Plimack ER, Choueiri TK, McDermott DF, Puzanov I, Fishman MN, Cho DC, Vaishampayan U, Rosbrook B, Fernandez KC, Tarazi JC, George S, Atkins MB. Angiogenic and immune-related biomarkers and outcomes following axitinib/pembrolizumab treatment in patients with advanced renal cell carcinoma. Clin Cancer Res. 2020 Nov 1;26(21):5598-5608.
Thadi A, Gleeson EM, Khalili M, Shaikh MF, Goldstein E, Morano WF, Daniels LM, Grandhi N, Glatthorn H, Richard SD, Campbell PM, Sarafraz-Yazdi E, Pincus MR, Bowne WB. Anti-Cancer Tumor Cell Necrosis of Epithelial Ovarian Cancer Cell Lines Depends on High Expression of HDM-2 Protein in Their Membranes. Ann Clin Lab Sci. 2020 Sep;50(5):611-624.
Li X, Fang P, Sun Y, Shao Y, Yang WY, Jiang X, Wang H, Yang X. Anti-inflammatory cytokines IL-35 and IL-10 block atherogenic lysophosphatidylcholine-induced, mitochondrial ROS-mediated innate immune activation, but spare innate immune memory signature in endothelial cells. Redox Biol. 2020 Jan;28:101373. PubMed Central PMCID: PMC6920093.
Pei J, Al-Saleem T, Uzzo RG, Dulaimi E, Testa JR, Wei S. Application of Chromosome Microarray Analysis for the Differential Diagnosis of Low-grade Renal Cell Carcinoma With Clear Cell and Papillary Features. Appl Immunohistochem Mol Morphol. 2020 Feb;28(2):123-129.
Liu M, Saredy J, Zhang R, Shao Y, Sun Y, Yang WY, Wang J, Liu L, Drummer Cth, Johnson C, Saaoud F, Lu Y, Xu K, Li L, Wang X, Jiang X, Wang H, Yang X. Approaching Inflammation Paradoxes-Proinflammatory Cytokine Blockages Induce Inflammatory Regulators. Front Immunol. 2020;11:554301. PubMed Central PMCID: PMC7604447.
Padhi A, Singh K, Franco-Barraza J, Marston DJ, Cukierman E, Hahn KM, Kapania RK, Nain AS. Author Correction: Force-exerting perpendicular lateral protrusions in fibroblastic cell contraction. Commun Biol. 2020 Aug 21;3(1):470.
Chandramouleeswaran PM, Guha M, Shimonosono M, Whelan KA, Maekawa H, Sachdeva UM, Ruthel G, Mukherjee S, Engel N, Gonzalez MV, Garifallou J, Ohashi S, Klein-Szanto AJ, Mesaros CA, Blair IA, Pellegrino da Silva R, Hakonarson H, Noguchi E, Baur JA, Nakagawa H. Autophagy mitigates ethanol-induced mitochondrial dysfunction and oxidative stress in esophageal keratinocytes. PLoS One. 2020;15(9):e0239625. PubMed Central PMCID: PMC7510980.
Nacson J, Di Marcantonio D, Wang Y, Bernhardy AJ, Clausen E, Hua X, Cai KQ, Martinez E, Feng W, Callen E, Wu W, Gupta GP, Testa JR, Nussenzweig A, Sykes SM, Johnson N. BRCA1 Mutational Complementation Induces Synthetic Viability. Mol Cell. 2020 Jun 4;78(5):951-959 e6. PubMed Central PMCID: PMC7418109.
Zhou X, Dou Q, Fan G, Zhang Q, Sanderford M, Kaya A, Johnson J, Karlsson EK, Tian X, Mikhalchenko A, Kumar S, Seluanov A, Zhang ZD, Gorbunova V, Liu X, Gladyshev VN. Beaver and Naked Mole Rat Genomes Reveal Common Paths to Longevity. Cell Rep. 2020 Jul 28;32(4):107949.
Flaig TW, Spiess PE, Agarwal N, Bangs R, Boorjian SA, Buyyounouski MK, Chang S, Downs TM, Efstathiou JA, Friedlander T, Greenberg RE, Guru KA, Guzzo T, Herr HW, Hoffman-Censits J, Hoimes C, Inman BA, Jimbo M, Kader AK, Lele SM, Michalski J, Montgomery JS, Nandagopal L, Pagliaro LC, Pal SK, Patterson A, Plimack ER, Pohar KS, Preston MA, Sexton WJ, Siefker-Radtke AO, Tward J, Wright JL, Gurski LA, Johnson-Chilla A. Bladder Cancer, Version 3.2020, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2020 Mar;18(3):329-354.
Saaoud F, Wang J, Iwanowycz S, Wang Y, Altomare D, Shao Y, Liu J, Blackshear PJ, Lessner SM, Murphy EA, Wang H, Yang X, Fan D. Bone marrow deficiency of mRNA decaying protein Tristetraprolin increases inflammation and mitochondrial ROS but reduces hepatic lipoprotein production in LDLR knockout mice. Redox Biol. 2020 Oct;37:101609. PubMed Central PMCID: PMC7767740.
Mancuso P, Chen C, Kaminski R, Gordon J, Liao S, Robinson JA, Smith MD, Liu H, Sariyer IK, Sariyer R, Peterson TA, Donadoni M, Williams JB, Siddiqui S, Bunnell BA, Ling B, MacLean AG, Burdo TH, Khalili K. CRISPR based editing of SIV proviral DNA in ART treated non-human primates. Nat Commun. 2020 Nov 27;11(1):6065. PubMed Central PMCID: PMC7695718.
Makhov P, Sohn JA, Serebriiskii IG, Fazliyeva R, Khazak V, Boumber Y, Uzzo RG, Kolenko VM. CRISPR/Cas9 genome-wide loss-of-function screening identifies druggable cellular factors involved in sunitinib resistance in renal cell carcinoma. Br J Cancer. 2020 Dec;123(12):1749-1756. PubMed Central PMCID: PMC7723036.
Alexander J, Cukierman E. Cancer Associated Fibroblast: Mediators of Tumorigenesis. Matrix Biol. 2020 May 22;91-92:19-34. PubMed Central PMCID: PMC7434664.
Lazarovici P, Marcinkiewicz C, Lelkes PI. Cell-Based Adhesion Assays for Isolation of Snake Venom's Integrin Antagonists. Methods Mol Biol. 2020;2068:205-223.
Wallis SL, Emmett EA, Hardy R, Casper BB, Blanchon DJ, Testa JR, Menges CW, Gonneau C, Jerolmack DJ, Seiphoori A, Steinhorn G, Berry TA. Challenging Global Waste Management - Bioremediation to Detoxify Asbestos. Frontiers in Environmental Science. 2020 Mar;8. PubMed Central PMCID: PMC7707057.
Beauchemin L, Slifker M, Rossell D, Font-Burgada J. Characterizing MHC-I Genotype Predictive Power for Oncogenic Mutation Probability in Cancer Patients. Methods Mol Biol. 2020;2131:185-198.
Jain R, Vijayvergia N, Devarajan K, Lewis B, Denlinger CS, Cohen SJ, Dotan E. Chemotherapy use and survival in older adults with metastatic pancreatic cancer in the combination therapy era. J Geriatr Oncol. 2020 May;11(4):640-646. PubMed Central PMCID: PMC7567610.
Gabitova-Cornell L, Surumbayeva A, Peri S, Franco-Barraza J, Restifo D, Weitz N, Ogier C, Goldman AR, Hartman TR, Francescone R, Tan Y, Nicolas E, Shah N, Handorf EA, Cai KQ, O'Reilly AM, Sloma I, Chiaverelli R, Moffitt RA, Khazak V, Fang CY, Golemis EA, Cukierman E, Astsaturov I. Cholesterol Pathway Inhibition Induces TGF-β Signaling to Promote Basal Differentiation in Pancreatic Cancer. Cancer Cell. 2020 Oct 12;38(4):567-583 e11. PubMed Central PMCID: PMC7572882.
Saaoud F, Drummer IVC, Shao Y, Sun Y, Lu Y, Xu K, Ni D, Jiang X, Wang H, Yang X. Circular RNAs are a novel type of non-coding RNAs in ROS regulation, cardiovascular metabolic inflammations and cancers. Pharmacol Ther. 2020 Oct 24:107715.
Gore JL, du Plessis M, Zhang J, Dai D, Thompson DJS, Karsh L, Lane B, Franks M, Chen DYT, Bianco FJ Jr, Brown G, Clark W, Kibel AS, Kim H, Lowrance W, Manoharan M, Maroni P, Perrapato S, Sieber P, Trabulsi EJ, Waterhouse R, Spratt DE, Davicioni E, Lotan Y, Lin DW. Clinical Utility of a Genomic Classifier in Men Undergoing Radical Prostatectomy: The PRO-IMPACT Trial. Pract Radiat Oncol. 2020 Mar - Apr;10(2):e82-e90.
Vickman RE, Faget DV, Beachy P, Beebe D, Bhowmick NA, Cukierman E, Deng WM, Granneman JG, Hildesheim J, Kalluri R, Lau KS, Lengyel E, Lundeberg J, Moscat J, Nelson PS, Pietras K, Politi K, Puré E, Scherz-Shouval R, Sherman MH, Tuveson D, Weeraratna AT, White RM, Wong MH, Woodhouse EC, Zheng Y, Hayward SW, Stewart SA. Deconstructing tumor heterogeneity: the stromal perspective. Oncotarget. 2020 Oct 6;11(40):3621-3632. PubMed Central PMCID: PMC7546755.
Miron B, Hoffman-Censits JH, Anari F, O'Neill J, Geynisman DM, Zibelman MR, Kutikov A, Viterbo R, Greenberg RE, Chen D, Lallas CD, Trabulsi EJ, Alpaugh RK, Dulaimi E, Golemis EA, Uzzo R, Ross EA, Plimack ER. Defects in DNA Repair Genes Confer Improved Long-term Survival after Cisplatin-based Neoadjuvant Chemotherapy for Muscle-invasive Bladder Cancer. Eur Urol Oncol. 2020 Aug;3(4):544-547. PubMed Central PMCID: PMC7689684.
Qian L, Soderquist C, Schrank-Hacker A, Strauser H, Dupoux V, Tang CN, Smith JR, Sun A, Majumdar S, Nguyen T, Widura S, Landsburg DJ, Schuster SJ, Baxter RHG, Bogusz AM. Deletion 20q12 is associated with histological transformation of nodal marginal zone lymphoma to diffuse large B-cell lymphoma. Am J Hematol. 2020 Mar;95(3):238-244.
Cunningham CM, Bellipanni G, Habas R, Balciunas D. Deletion of morpholino binding sites (DeMOBS) to assess specificity of morphant phenotypes. Sci Rep. 2020 Sep 21;10(1):15366. PubMed Central PMCID: PMC7506532.
Gutiérrez-Diez PJ, Russo J. Design of personalized cancer treatments by use of optimal control problems: The case of chronic myeloid leukemia. Math Biosci Eng. 2020 Jul 9;17(5):4773-4800.
Ruggeri JM, Franco-Barraza J, Sohail A, Zhang Y, Long D, Pasca di Magliano M, Cukierman E, Fridman R, Crawford HC. Discoidin Domain Receptor 1 (DDR1) is Necessary for Tissue Homeostasis in Pancreatic Injury and Pathogenesis of Pancreatic Ductal Adenocarcinoma. Am J Pathol. 2020 Apr 24;190(8):1735-1751. PubMed Central PMCID: PMC7416078.
Liu F, Dai S, Feng D, Qin Z, Peng X, Sakamuri Ssvp, Ren M, Huang L, Cheng M, Mohammad KE, Qu P, Chen Y, Zhao C, Zhu F, Liang S, Aktas BH, Yang X, Wang H, Katakam PVG, Busija DW, Fischer T, Datta PK, Rappaport J, Gao B, Qin X. Distinct fate, dynamics and niches of renal macrophages of bone marrow or embryonic origins. Nat Commun. 2020 May 8;11(1):2280. PubMed Central PMCID: PMC7210253.
Rosenberg J, Sridhar SS, Zhang J, Smith D, Ruether D, Flaig TW, Baranda J, Lang J, Plimack ER, Sangha R, Heath EI, Merchan J, Quinn DI, Srinivas S, Milowsky M, Wu C, Gartner EM, Zuo P, Melhem-Bertrandt A, Petrylak DP. EV-101: A Phase I Study of Single-Agent Enfortumab Vedotin in Patients With Nectin-4-Positive Solid Tumors, Including Metastatic Urothelial Carcinoma. J Clin Oncol. 2020 Apr 1;38(10):1041-1049. PubMed Central PMCID: PMC7106979.
Marcinkiewicz C, Lelkes PI, Sternberg M, Feuerstein GZ. Effects of Fluorescent Diamond Particles FDP-NV-800nm on Essential Biochemical Functions of Primary Human Umbilical Vein Cells and Human Hepatic Cell Line, HepG-2 in vitro (Part VI): Acute Biocompatibility Studies. Nanotechnol Sci Appl. 2020;13:103-118. PubMed Central PMCID: PMC7547810.
Zhang R, Saredy J, Shao Y, Yao T, Liu L, Saaoud F, Yang WY, Sun Y, Johnson C, Drummer Cth, Fu H, Lu Y, Xu K, Liu M, Wang J, Cutler E, Yu D, Jiang X, Li Y, Li R, Wang L, Choi ET, Wang H, Yang X. End-stage renal disease is different from chronic kidney disease in upregulating ROS-modulated proinflammatory secretome in PBMCs - A novel multiple-hit model for disease progression. Redox Biol. 2020 Jul;34:101460. PubMed Central PMCID: PMC7327976.
Franco-Barraza J, Raghavan KS, Luong T, Cukierman E. Engineering clinically-relevant human fibroblastic cell-derived extracellular matrices. Methods Cell Biol. 2020;156:109-160. PubMed Central PMCID: PMC7298733.
Oss-Ronen L, Redden RA, Lelkes PI. Enhanced Induction of Definitive Endoderm Differentiation of Mouse Embryonic Stem Cells in Simulated Microgravity. Stem Cells Dev. 2020 Oct 1;29(19):1275-1284.
Mani S, Ghosh J, Coutifaris C, Sapienza C, Mainigi M. Epigenetic changes and assisted reproductive technologies. Epigenetics. 2020 Jan- Feb;15(1-2):12-25. PubMed Central PMCID: PMC6961665.
Ghatalia P, Zibelman M, Geynisman DM, Plimack ER. First-line Immunotherapy in Metastatic Urothelial Carcinoma. Eur Urol Focus. 2020 Jan 15;6(1):45-47.
Simonet JC, Burrell AL, Kollman JM, Peterson JR. Freedom of assembly: metabolic enzymes come together. Mol Biol Cell. 2020 Jun 1;31(12):1201-1205. PubMed Central PMCID: PMC7353150.
Perrin L, Bayarmagnai B, Gligorijevic B. Frontiers in Intravital Multiphoton Microscopy of Cancer. Cancer Rep (Hoboken). 2020 Feb;3(1):e1192. PubMed Central PMCID: PMC7197974.
Kurimchak AM, Herrera-Montavez C, Brown J, Johnson KJ, Sodi V, Srivastava N, Kumar V, Deihimi S, O'Brien S, Peri S, Mantia-Smaldone GM, Jain A, Winters RM, Cai KQ, Chernoff J, Connolly DC, Duncan JS. Functional proteomics interrogation of the kinome identifies MRCKA as a therapeutic target in high-grade serous ovarian carcinoma. Sci Signal. 2020 Feb 18;13(619). PubMed Central PMCID: PMC7294993.
Pyott SJ, van Tuinen M, Screven LA, Schrode KM, Bai JP, Barone CM, Price SD, Lysakowski A, Sanderford M, Kumar S, Santos-Sacchi J, Lauer AM, Park TJ. Functional, Morphological, and Evolutionary Characterization of Hearing in Subterranean, Eusocial African Mole-Rats. Curr Biol. 2020 Nov 16;30(22):4329-4341 e4.
Karakasheva TA, Kijima T, Shimonosono M, Maekawa H, Sahu V, Gabre JT, Cruz-Acuna R, Giroux V, Sangwan V, Whelan KA, Natsugoe S, Yoon AJ, Philipone E, Klein-Szanto AJ, Ginsberg GG, Falk GW, Abrams JA, Que J, Basu D, Ferri L, Diehl JA, Bass AJ, Wang TC, Rustgi AK, Nakagawa H. Generation and Characterization of Patient-Derived Head and Neck, Oral, and Esophageal Cancer Organoids. Curr Protoc Stem Cell Biol. 2020 Jun;53(1):e109. PubMed Central PMCID: PMC7350550.
Clarke TL, Tang R, Chakraborty D, Van Rechem C, Ji F, Mishra S, Ma A, Kaniskan HU, Jin J, Lawrence MS, Sadreyev RI, Whetstine JR. Histone Lysine Methylation Dynamics Control EGFR DNA Copy Number Amplification. Cancer Discov. 2020 Feb;10(2):306-325. PubMed Central PMCID: PMC7271978.
Shen W, Gao C, Cueto R, Liu L, Fu H, Shao Y, Yang WY, Fang P, Choi ET, Wu Q, Yang X, Wang H. Homocysteine-methionine cycle is a metabolic sensor system controlling methylation-regulated pathological signaling. Redox Biol. 2020 Jan;28:101322. PubMed Central PMCID: PMC6812029.
Gary JM, Simmons JK, Xu J, Zhang S, Peat TJ, Watson N, Gamache BJ, Zhang K, Kovalchuk AL, Michalowski AM, Chen JQ, Thaiwong T, Kiupel M, Gaikwad S, Etienne M, Simpson RM, Dubois W, Testa JR, Mock BA. Hypomorphic mTOR Downregulates CDK6 and Delays Thymic Pre-T LBL Tumorigenesis. Mol Cancer Ther. 2020 Oct;19(10):2221-2232.
Miller AL, Pasternak JA, Medeiros NJ, Nicastro LK, Tursi SA, Hansen EG, Krochak R, Sokaribo AS, MacKenzie KD, Palmer MB, Herman DJ, Watson NL, Zhang Y, Wilson HL, Wilson RP, White AP, Tükel Ç. In vivo synthesis of bacterial amyloid curli contributes to joint inflammation during S. Typhimurium infection. PLoS Pathog. 2020 Jul;16(7):e1008591. PubMed Central PMCID: PMC7347093.
Martinez Chanza N, Werner L, Plimack E, Yu EY, Alva AS, Crabb SJ, Powles T, Rosenberg JE, Baniel J, Vaishampayan UN, Berthold DR, Ladoire S, Hussain SA, Milowsky MI, Agarwal N, Necchi A, Pal SK, Sternberg CN, Bellmunt J, Galsky MD, Harshman LC. Incidence, Patterns, and Outcomes with Adjuvant Chemotherapy for Residual Disease After Neoadjuvant Chemotherapy in Muscle-invasive Urinary Tract Cancers. Eur Urol Oncol. 2020 0ct;3(5):671-679.
Strathearn LS, Stepanov AI, Font-Burgada J. Inflammation in Primary and Metastatic Liver Tumorigenesis-Under the Influence of Alcohol and High-Fat Diets. Nutrients. 2020 Mar 27;12(4). PubMed Central PMCID: PMC7230665.
Sun L, Wang X, Saredy J, Yuan Z, Yang X, Wang H. Innate-adaptive immunity interplay and redox regulation in immune response. Redox Biol. 2020 Oct 10;37:101759. PubMed Central PMCID: PMC7575795.
Ghatalia P, Plimack ER. Integration of Immunotherapy Into the Treatment of Advanced Urothelial Carcinoma. J Natl Compr Canc Netw. 2020 Mar;18(3):355-361.
Fu H, Sun Y, Shao Y, Saredy J, Cueto R, Liu L, Drummer Cth, Johnson C, Xu K, Lu Y, Li X, Meng S, Xue ER, Tan J, Jhala NC, Yu D, Zhou Y, Bayless KJ, Yu J, Rogers TJ, Hu W, Snyder NW, Sun J, Qin X, Jiang X, Wang H, Yang X. Interleukin 35 Delays Hindlimb Ischemia-Induced Angiogenesis Through Regulating ROS-Extracellular Matrix but Spares Later Regenerative Angiogenesis. Front Immunol. 2020;11:595813. PubMed Central PMCID: PMC7591706.
Madnick D, Handorf E, Ortiz A, Sorice K, Nagappan L, Moccia M, Cheema K, Vijayvergia N, Dotan E, Lynch SM. Investigating disparities: the effect of social environment on pancreatic cancer survival in metastatic patients. J Gastrointest Oncol. 2020 Aug;11(4):633-643. PubMed Central PMCID: PMC7475328.
Kurimchak AM, Kumar V, Herrera-Montávez C, Johnson KJ, Srivastava N, Devarajan K, Peri S, Cai KQ, Mantia-Smaldone GM, Duncan JS. Kinome Profiling of Primary Endometrial Tumors Using Multiplexed Inhibitor Beads and Mass Spectrometry Identifies SRPK1 As Candidate Therapeutic Target. Mol Cell Proteomics. 2020 Dec;19(12):2068-2089. PubMed Central PMCID: PMC7710141.
Fagenson AM, Xu K, Saaoud F, Nanayakkara G, Jhala NC, Liu L, Drummer C, Sun Y, Lau KN, Di Carlo A, Jiang X, Wang H, Karhadkar SS, Yang X. Liver Ischemia Reperfusion Injury, Enhanced by Trained Immunity, Is Attenuated in Caspase 1/Caspase 11 Double Gene Knockout Mice. Pathogens. 2020 Oct 24;9(11). PubMed Central PMCID: PMC7692674.
Vuky J, Balar AV, Castellano D, O'Donnell PH, Grivas P, Bellmunt J, Powles T, Bajorin D, Hahn NM, Savage MJ, Fang X, Godwin JL, Frenkl TL, Homet Moreno B, de Wit R, Plimack ER. Long-Term Outcomes in KEYNOTE-052: Phase II Study Investigating First-Line Pembrolizumab in Cisplatin-Ineligible Patients With Locally Advanced or Metastatic Urothelial Cancer. J Clin Oncol. 2020 Aug 10;38(23):2658-2666. PubMed Central PMCID: PMC5568632.
Guo DC, Qu YH, Yang YJ, Yang ZJ. Medulloblastoma cells resemble neuronal progenitors in their differentiation. Molecular & Cellular Oncology. 2020 Sep 6;7(6):1810514. PubMed Central PMCID: PMC7671073.
Sun L, Yang X, Yuan Z, Wang H. Metabolic Reprogramming in Immune Response and Tissue Inflammation. Arterioscler Thromb Vasc Biol. 2020 Sep;40(9):1990-2001. PubMed Central PMCID: PMC7484156.
Andrews AJ, Young NL. Methodological innovations drive conceptual innovations forward in chromatin biology. Methods. 2020 Dec 1;184:1-3.
Nakagawa H, Kasagi Y, Karakasheva TA, Hara T, Aaron B, Shimonosono M, Kijima T, Giroux V, Bailey D, Wilkins B, Abrams JA, Falk GW, Aceves SS, Spergel JM, Hamilton KE, Whelan KA, Muir AB. Modeling Epithelial Homeostasis and Reactive Epithelial Changes in Human and Murine Three-Dimensional Esophageal Organoids. Curr Protoc Stem Cell Biol. 2020 Mar;52(1):e106. PubMed Central PMCID: PMC7288850.
Stecher G, Tamura K, Kumar S. Molecular Evolutionary Genetics Analysis (MEGA) for macOS. Mol Biol Evol. 2020 Apr 1;37(4):1237-1239. PubMed Central PMCID: PMC7086165.
Nilov D, Maluchenko N, Kurgina T, Pushkarev S, Lys A, Kutuzov M, Gerasimova N, Feofanov A, Svedas V, Lavrik O, Studitsky VM. Molecular Mechanisms of PARP-1 Inhibitor 7-Methylguanine. Int J Mol Sci. 2020 Mar 20;21(6). PubMed Central PMCID: PMC7139824.
Tang T, Cheng X, Truong B, Sun L, Yang X, Wang H. Molecular basis and therapeutic implications of CD40/CD40L immune checkpoint. Pharmacol Ther. 2020 Oct 20:107709.
Somarelli JA, Gardner H, Cannataro VL, Gunady EF, Boddy AM, Johnson NA, Fisk JN, Gaffney SG, Chuang JH, Li S, Ciccarelli FD, Panchenko AR, Megquier K, Kumar S, Dornburg A, DeGregori J, Townsend JP. Molecular biology and evolution of cancer: from discovery to action. Mol Biol Evol. 2020 Feb 1;37(2):320-326. PubMed Central PMCID: PMC6993850.
Nejati R, Wei S, Uzzo RG, Poureghbali S, Pei J, Talarchek JN, Ruth K, Dulaimi E, Kutikov A, Testa JR, Al-Saleem T. Monosomy of Chromosome 9 Is Associated With Higher Grade, Advanced Stage, and Adverse Outcome in Clear-cell Renal Cell Carcinoma. Clin Genitourin Cancer. 2020 Feb;18(1):56-61. PubMed Central PMCID: PMC7781234.
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Feldman AM, Gordon J, Wang J, Song J, Zhang XQ, Myers VD, Tomar D, Gerhard GS, Khalili K, Cheung JY. Novel BAG3 Variants in African American Patients With Cardiomyopathy: Reduced β-Adrenergic Responsiveness in Excitation-Contraction. J Card Fail. 2020 Dec;26(12):1075-1085. PubMed Central PMCID: PMC7736114.
Correa AF, Ruth KJ, Al-Saleem T, Pei J, Dulaimi E, Kister D, Collins M, Abbosh PH, Slifker MJ, Ross E, Uzzo RG, Testa JR. Overall tumor genomic instability: an important predictor of recurrence-free survival in patients with localized clear cell renal cell carcinoma. Cancer Biol Ther. 2020 May 3;21(5):424-431. PubMed Central PMCID: PMC7515487.
Nam H, Kundu A, Brinkley GJ, Chandrashekar DS, Kirkman RL, Chakravarthi Bvsk, Orlandella RM, Norian LA, Sonpavde G, Ghatalia P, Fei F, Wei S, Varambally S, Sudarshan S. PGC1α suppresses kidney cancer progression by inhibiting collagen-induced SNAIL expression. Matrix Biol. 2020 Jul;89:43-58. PubMed Central PMCID: PMC7712461.
Weishaupt C, Mastrofrancesco A, Metze D, Kemper B, Stegemann A, Picardo M, Klein-Szanto AJP, Bohm M. Paired Basic Amino Acid-cleaving Enzyme 4 (PCSK6): An Emerging New Target Molecule in Human Melanoma. Acta Derm Venereol. 2020 May;100(10):adv00157.
Kumar S, Chroni A, Tamura K, Sanderford M, Oladeinde O, Aly V, Vu T, Miura S. PathFinder: Bayesian inference of clone migration histories in cancer. Bioinformatics. 2020 Dec 30;36(Supplement_2):i675-i683. PubMed Central PMCID: PMC7773489.
Bryce AH, Chen YH, Liu G, Carducci MA, Jarrard DM, Garcia JA, Dreicer R, Hussain M, Eisenberger MA, Plimack ER, Vogelzang NJ, DiPaola RS, Harshman L, Sweeney CJ. Patterns of Cancer Progression of Metastatic Hormone-sensitive Prostate Cancer in the ECOG3805 CHAARTED Trial. Eur Urol Oncol. 2020 Dec;3(6):717-724. PubMed Central PMCID: PMC7738423.
Grivas P, Plimack ER, Balar AV, Castellano D, O'Donnell PH, Bellmunt J, Powles T, Hahn NM, de Wit R, Bajorin DF, Ellison MC, Frenkl TL, Godwin JL, Vuky J. Pembrolizumab as First-line Therapy in Cisplatin-ineligible Advanced Urothelial Cancer (KEYNOTE-052): Outcomes in Older Patients by Age and Performance Status. Eur Urol Oncol. 2020 Jun;3(3):351-359.
Vijayvergia N, Dasari A, Deng M, Litwin S, Al-Toubah T, Alpaugh RK, Dotan E, Hall MJ, Ross NM, Runyen MM, Denlinger CS, Halperin DM, Cohen SJ, Engstrom PF, Strosberg JR. Pembrolizumab monotherapy in patients with previously treated metastatic high-grade neuroendocrine neoplasms: joint analysis of two prospective, non-randomised trials. Br J Cancer. 2020 Mar 10;122(9):1309-1314. PubMed Central PMCID: PMC7188798.
Powles T, Plimack ER, Soulières D, Waddell T, Stus V, Gafanov R, Nosov D, Pouliot F, Melichar B, Vynnychenko I, Azevedo SJ, Borchiellini D, McDermott RS, Bedke J, Tamada S, Yin L, Chen M, Molife LR, Atkins MB, Rini BI. Pembrolizumab plus axitinib versus sunitinib monotherapy as first-line treatment of advanced renal cell carcinoma (KEYNOTE-426): extended follow-up from a randomised, open-label, phase 3 trial. Lancet Oncol. 2020 Dec;21(12):1563-1573.
Whelan KA, Godwin BC, Wilkins B, Elci OU, Benitez A, DeMarshall M, Sharma M, Gross J, Klein-Szanto AJ, Liacouras CA, Dellon ES, Spergel JM, Falk GW, Muir AB, Nakagawa H. Persistent Basal Cell Hyperplasia Is Associated With Clinical and Endoscopic Findings in Patients With Histologically Inactive Eosinophilic Esophagitis. Clin Gastroenterol Hepatol. 2020 Jun;18(7):1475-1482 e1. PubMed Central PMCID: PMC7058491.
Margulis V, Puligandla M, Trabulsi EJ, Plimack ER, Kessler ER, Matin SF, Godoy G, Alva A, Hahn NM, Carducci MA, Hoffman-Censits J. Phase II Trial of Neoadjuvant Systemic Chemotherapy Followed by Extirpative Surgery in Patients with High Grade Upper Tract Urothelial Carcinoma. J Urol. 2020 Apr;203(4):690-698. PubMed Central PMCID: PMC7735436.
Nakaya MA, Gudmundsson KO, Komiya Y, Keller JR, Habas R, Yamaguchi TP, Ajima R. Placental defects lead to embryonic lethality in mice lacking the Formin and PCP proteins Daam1 and Daam2. PLoS One. 2020;15(4):e0232025. PubMed Central PMCID: PMC7192421.
Miura S, Vu T, Deng J, Buturla T, Oladeinde O, Choi J, Kumar S. Power and pitfalls of computational methods for inferring clone phylogenies and mutation orders from bulk sequencing data. Sci Rep. 2020 Feb 26;10(1):3498. PubMed Central PMCID: PMC7044161.
Testa JR, Berns A. Preclinical Models of Malignant Mesothelioma. Front Oncol. 2020;10:101. PubMed Central PMCID: PMC7026500.
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Zhang T, Pabla S, Lenzo FL, Conroy JM, Nesline MK, Glenn ST, Papanicolau-Sengos A, Burgher B, Giamo V, Andreas J, Wang Y, Bshara W, Madden KG, Shirai K, Dragnev K, Tafe LJ, Gupta R, Zhu J, Labriola M, McCall S, George DJ, Ghatalia P, Dayyani F, Edwards R, Park MS, Singh R, Jacob R, George S, Xu B, Zibelman M, Kurzrock R, Morrison C. Proliferative potential and response to nivolumab in clear cell renal cell carcinoma patients. OncoImmunology. 2020 Jun 10;9(1):1773200. PubMed Central PMCID: PMC7458647.
Cannon AC, Uribe-Alvarez C, Chernoff J. RAC1 as a Therapeutic Target in Malignant Melanoma. Trends Cancer. 2020 Jun;6(6):478-488. PubMed Central PMCID: PMC7380552.
Sun Y, Lu Y, Saredy J, Wang X, Drummer Iv C, Shao Y, Saaoud F, Xu K, Liu M, Yang WY, Jiang X, Wang H, Yang X. ROS systems are a new integrated network for sensing homeostasis and alarming stresses in organelle metabolic processes. Redox Biol. 2020 Oct;37:101696. PubMed Central PMCID: PMC7767745.
Gligorijevic B. Real-time, high-resolution microscopy of invasive cancer cells in the tumor microenvironment context. J Biomol Tech. 2020 Aug;31(Suppl):S40. PubMed Central PMCID: PMC7424851.
Tao Q, Barba-Montoya J, Huuki LA, Durnan MK, Kumar S. Relative efficiencies of simple and complex substitution models in estimating divergence times in phylogenomics. Mol Biol Evol. 2020 Mar 2;37(6):1819-1831. PubMed Central PMCID: PMC7253201.
Tao Q, Tamura K, Mello B, Kumar S. Reliable confidence intervals for RelTime estimates of evolutionary divergence times. Mol Biol Evol. 2020 Jan 1;37(1):280-290. PubMed Central PMCID: PMC6984362.
Geynisman DM, Kadow BT, Shuch BM, Boorjian SA, Matin SF, Rampersaud E, Milestone BN, Plimack ER, Zibelman MR, Kutikov A, Smaldone MC, Chen DY, Viterbo R, Joshi S, Greenberg RE, Malizzia L, McGowan T, Ross EA, Uzzo RG. Reply by Authors. J Urol. 2020 Jun 23:101097ju000000000000106502.
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Figlin RA, Tannir NM, Uzzo RG, Tykodi SS, Chen DYT, Master V, Kapoor A, Vaena D, Lowrance WT, DeBenedette M, Gamble A, Plachco A, Norris MS, Horvatinovich J, Tcherepanova IY, Nicolette CA, Wood CG. Results of the ADAPT phase 3 study of Rocapuldencel-T in combination with sunitinib as first-line therapy in patients with metastatic renal cell carcinoma. Clin Cancer Res. 2020 May 15;26(10):2327-2336.
Pan L, Lin Z, Tang X, Tian J, Zheng Q, Jing J, Xie L, Chen H, Lu Q, Wang H, Li Q, Han Y, Ji Y. S-Nitrosylation of Plastin-3 Exacerbates Thoracic Aortic Dissection Formation via Endothelial Barrier Dysfunction. Arterioscler Thromb Vasc Biol. 2020 Jan;40(1):175-188.
Tang X, Pan L, Zhao S, Dai F, Chao M, Jiang H, Li X, Lin Z, Huang Z, Meng G, Wang C, Chen C, Liu J, Wang X, Ferro A, Wang H, Chen H, Gao Y, Lu Q, Xie L, Han Y, Ji Y. SNO-MLP (S-Nitrosylation of Muscle LIM Protein) Facilitates Myocardial Hypertrophy Through TLR3 (Toll-Like Receptor 3)-Mediated RIP3 (Receptor-Interacting Protein Kinase 3) and NLRP3 (NOD-Like Receptor Pyrin Domain Containing 3) Inflammasome Activation. Circulation. 2020 Mar 24;141(12):984-1000.
Chandrashekar P, Ahmadinejad N, Wang J, Sekulic A, Egan JB, Asmann YW, Kumar S, Maley C, Liu L. Somatic selection distinguishes oncogenes and tumor suppressor genes. Bioinformatics. 2020 Mar 1;36(6):1712-1717. PubMed Central PMCID: PMC7703750.
Phelan MA, Kruczek K, Wilson JH, Brooks MJ, Drinnan CT, Regent F, Gerstenhaber JA, Swaroop A, Lelkes PI, Li T. Soy Protein Nanofiber Scaffolds for Uniform Maturation of Human Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium. Tissue Eng Part C Methods. 2020 Aug;26(8):433-446. PubMed Central PMCID: PMC7462036.
Geynisman DM, Kadow BT, Shuch BM, Boorjian SA, Matin SF, Rampersaud E, Milestone BN, Plimack ER, Zibelman MR, Kutikov A, Smaldone MC, Chen DY, Viterbo R, Joshi S, Greenberg RE, Malizzia L, McGowan T, Ross EA, Uzzo RG. Sporadic Angiomyolipomas (AMLs) Growth Kinetics While on Everolimus (SAGE): Results of a Phase II Trial. J Urol. 2020 Sep;204(3):531-537. PubMed Central PMCID: PMC7695484.
Mookerjee-Basu J, Hooper R, Gross S, Schultz B, Go CK, Samakai E, Ladner J, Nicolas E, Tian Y, Zhou B, Zaidi MR, Tourtellotte W, He S, Zhang Y, Kappes DJ, Soboloff J. Suppression of Ca(2+) signals by EGR4 controls Th1 differentiation and anti-cancer immunity in vivo. EMBO Rep. 2020 May 6;21(5):e48904. PubMed Central PMCID: PMC7202224.
Cheng Y, Franco-Barraza J, Wang Y, Zheng C, Zhang L, Qu Y, Long Y, Cukierman E, Yang ZJ. Sustained hedgehog signaling in medulloblastoma tumoroids is attributed to stromal astrocytes and astrocyte-derived extracellular matrix. Lab Invest. 2020 Sep;100(9):1208-1222. PubMed Central PMCID: PMC7442735.
Girardi DM, Ghatalia P, Singh P, Iyer G, Sridhar SS, Apolo AB. Systemic therapy in bladder preservation. Urol Oncol. 2020 Nov 19.
Zhang Z, Liu S, Zhang B, Qiao L, Zhang Y, Zhang Y. T Cell Dysfunction and Exhaustion in Cancer. Front Cell Dev Biol. 2020;8:17. PubMed Central PMCID: PMC7027373.
Vijayvergia N, Dasari A. Targeted Therapies in the Management of Well-Differentiated Digestive and Lung Neuroendocrine Neoplasms. Curr Treat Options Oncol. 2020 Oct 7;21(12):96. PubMed Central PMCID: PMC7592099.
Thadi A, Lewis L, Goldstein E, Aggarwal A, Khalili M, Steele L, Polyak B, Seydafkan S, Bluth MH, Ward KA, Styler M, Campbell PM, Pincus MR, Bowne WB. Targeting Membrane HDM-2 by PNC-27 Induces Necrosis in Leukemia Cells But Not in Normal Hematopoietic Cells. Anticancer Res. 2020 Sep;40(9):4857-4867.
Avkshtol V, Ruth KJ, Ross EA, Hallman MA, Greenberg RE, Price RA Jr, Leachman B, Uzzo RG, Ma C, Chen D, Geynisman DM, Sobczak ML, Zhang E, Wong JK, Pollack A, Horwitz EM. Ten-Year Update of a Randomized, Prospective Trial of Conventional Fractionated Versus Moderate Hypofractionated Radiation Therapy for Localized Prostate Cancer. J Clin Oncol. 2020 May 20;38(15):1676-1684. PubMed Central PMCID: PMC7238488.
Kantidze OL, Gurova KV, Studitsky VM, Razin SV. The 3D Genome as a Target for Anticancer Therapy. Trends Mol Med. 2020 Feb;26(2):141-149.
Sousa GL, Bishnoi R, Baxter RHG, Povelones M. The CLIP-domain serine protease CLIPC9 regulates melanization downstream of SPCLIP1, CLIPA8, and CLIPA28 in the malaria vector Anopheles gambiae. PLoS Pathog. 2020 Oct;16(10):e1008985. PubMed Central PMCID: PMC7580898.
Lubas MJ, Kumar SS. The Combined Use of SBRT and Immunotherapy-a Literature Review. Curr Oncol Rep. 2020 Sep 15;22(12):117.
Malyuchenko NV, Koshkina DO, Korovina AN, Gerasimova NS, Kirpichnikov MP, Studitsky VM, Feofanov AV. The Effect of Gossypol on the Structure of Nucleosomes. Moscow University Biological Sciences Bulletin. 2020;75(3):142-146.
Dunlevy KL, Medvedeva V, Wilson JE, Hoque M, Pellegrin T, Maynard A, Kremp MM, Wasserman JS, Poleshko A, Katz RA. The PRR14 heterochromatin tether encodes modular domains that mediate and regulate nuclear lamina targeting. J Cell Sci. 2020 May 27;133(10). PubMed Central PMCID: PMC7272351.
Campitelli P, Modi T, Kumar S, Ozkan SB. The Role of Conformational Dynamics and Allostery in Modulating Protein Evolution. Annu Rev Biophys. 2020 May 6;49:267-288.
Feuerstein GZ, Mansfield MA, Lelkes PI, Alesci S, Marcinkiewicz C, Butlin N, Sternberg M. The Use of Near-Infrared Light-Emitting Fluorescent Nanodiamond Particles to Detect Ebola Virus Glycoprotein: Technology Development and Proof of Principle. Int J Nanomedicine. 2020;15:7583-7599. PubMed Central PMCID: PMC7548262.
Van Rechem C, Ji F, Mishra S, Chakraborty D, Murphy SE, Dillingham ME, Sadreyev RI, Whetstine JR. The lysine demethylase KDM4A controls the cell-cycle expression of replicative canonical histone genes. Biochim Biophys Acta Gene Regul Mech. 2020 Oct;1863(10):194624.
Muir AB, Whelan KA, Dougherty MK, Aaron B, Navarre B, Aceves SS, Dellon ES, Jensen ET. The potential for malignancy from atopic disorders and allergic inflammation: A systematic review and meta-analysis. Clin Exp Allergy. 2020 feb;50(2):147-159. PubMed Central PMCID: PMC6994341.
Zhang R, Xu K, Shao Y, Sun Y, Saredy J, Cutler E, Yao T, Liu M, Liu L, Drummer Iv C, Lu Y, Saaoud F, Ni D, Wang J, Li Y, Li R, Jiang X, Wang H, Yang X. Tissue Treg Secretomes and Transcription Factors Shared With Stem Cells Contribute to a Treg Niche to Maintain Treg-Ness With 80% Innate Immune Pathways, and Functions of Immunosuppression and Tissue Repair. Front Immunol. 2020;11:632239. PubMed Central PMCID: PMC7892453.
Zhu Z, Achreja A, Meurs N, Animasahun O, Owen S, Mittal A, Parikh P, Lo TW, Franco-Barraza J, Shi J, Gunchick V, Sherman MH, Cukierman E, Pickering AM, Maitra A, Sahai V, Morgan MA, Nagrath S, Lawrence TS, Nagrath D. Tumour-reprogrammed stromal BCAT1 fuels branched-chain ketoacid dependency in stromal-rich PDAC tumours. Nat Metab. 2020 Aug;2(8):775-792. PubMed Central PMCID: PMC7438275.
Kurian J, Yuko AE, Kasatkin N, Rigaud VOC, Busch K, Harlamova D, Wagner M, Recchia FA, Wang H, Mohsin S, Houser SR, Khan M. Uncoupling protein 2-mediated metabolic adaptations define cardiac cell function in the heart during transition from young to old age. Stem Cells Transl Med. 2020 Sep 10. PubMed Central PMCID: PMC7780806.
Barba-Montoya J, Tao Q, Kumar S. Using a GTR+Γ substitution model for dating sequence divergence when stationarity and time-reversibility assumptions are violated. Bioinformatics. 2020 Dec 30;36(Supplement_2):i884-i894. PubMed Central PMCID: PMC7773479.
Shao Y, Saredy J, Yang WY, Sun Y, Lu Y, Saaoud F, Drummer Cth, Johnson C, Xu K, Jiang X, Wang H, Yang X. Vascular Endothelial Cells and Innate Immunity. Arterioscler Thromb Vasc Biol. 2020 Jun;40(6):e138-e152. PubMed Central PMCID: PMC7263359.
Leitner T, Kumar S. Where Did SARS-CoV-2 Come From?. Mol Biol Evol. 2020 Sep 1;37(9):2463-2464. PubMed Central PMCID: PMC7454771.
Tan Y, Sementino E, Liu Z, Cai KQ, Testa JR. Wnt signaling mediates oncogenic synergy between Akt and Dlx5 in T-cell lymphomagenesis by enhancing cholesterol synthesis. Sci Rep. 2020 Sep 28;10(1):15837. PubMed Central PMCID: PMC7522078.
Ozdener MH, Donadoni M, Cicalese S, Spielman AI, Garcia-Blanco A, Gordon J, Sariyer IK. Zika virus infection in chemosensory cells. J Neurovirol. 2020 Mar 6;26(3):371-381. PubMed Central PMCID: PMC7332368.
2017
Natsuizaka M, Whelan KA, Kagawa S, Tanaka K, Giroux V, Chandramouleeswaran PM, Long A, Sahu V, Darling DS, Que J, Yang Y, Katz JP, Wileyto EP, Basu D, Kita Y, Natsugoe S, Naganuma S, Klein-Szanto AJ, Diehl JA, Bass AJ, Wong KK, Rustgi AK, Nakagawa H. Interplay between Notch1 and Notch3 promotes EMT and tumor initiation in squamous cell carcinoma. Nat Commun. 2017 Nov 24;8(1):1758. PubMed Central PMCID: PMC5700926.