This is an archive of papers published by the staff and faculty of Fox Chase Cancer Center. For questions about content, please contact Talbot Research Library
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Gaskin DJ , Weinfurt KR , Castel LD , DePuy V , Li Y , Balshem A , Benson A , Burnett CB , Corbett S , Marshall J , Slater E , Sulmasy DR , Van Echo D , Meropol NJ , Schulman KA
An exploration of relative health stock in advanced cancer patients
Medical Decision Making. 2004 Nov-Dec;24(6) :614-624
AbstractObjective. The authors sought to empirically test whether relative health stock, a measure of patients' sense of loss in their health due to illness, influences the treatment decisions of patients facing life-threatening, conditions. Specifically, they estimated the effect of relative health stock on advanced cancer patients' decisions to participate in phase I clinical trials. Method. A multicenter study was conducted to survey 328 advanced cancer patients who were offered the opportunity to participate in phase I trials. The authors asked patients to estimate the probabilities of therapeutic benefits and toxicity, their relative health stock, risk preference, and the importance of quality of life. Results. Controlling for health-related quality of life, an increase in relative health stock by 10 percentage points reduced the odds of choosing to participate in a phase I trial by 16% (odds ratio = 0.84, 95% confidence interval = 0.72, 0,97). Conclusion. Relative health stock affects advanced cancer patients' treatment decisions.