This is an archive of papers published by the staff and faculty of Fox Chase Cancer Center. For questions about content, please contact Talbot Research Library
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Miyamoto DT , Abbosh PH , West CML , Mouw KW
Bladder preservation: Translating discovery for clinical impact in urothelial cancer
Urol Oncol. 2021 Apr;39(4) :201-208
PMID: 33257220 URL: https://www.ncbi.nlm.nih.gov/pubmed/33257220
AbstractMuscle-invasive bladder cancer can be treated with either radical cystectomy or bladder preservation approaches, and there is a need for reliable biomarkers to guide the optimal choice of therapy. The recent elucidation of the genomic landscape and biological drivers of bladder cancer has enabled the identification of tumor molecular features that may be helpful in driving clinical decision-making. Here, we summarize recent efforts to develop molecular biomarkers that could be leveraged to guide therapeutic decisions, post-treatment monitoring, and the optimal use of bladder preservation approaches for the effective treatment of muscle-invasive bladder cancer. (C) 2020 Elsevier Inc. All rights reserved.
NotesMiyamoto, David T. Abbosh, Philip H. West, Catharine M. L. Mouw, Kent W. Mouw, Kent/0000-0001-7939-7343 1873-2496 Review Urol Oncol. 2021 Apr;39(4):201-208. doi: 10.1016/j.urolonc.2020.11.021. Epub 2020 Nov 28.