FCCC LOGO Faculty Publications
Bernhardt D , Wick W , Weiss SE , Sahgal A , Lo SS , Suh JH , Chang EL , Foote M , Perry J , Meyer B , Vajkoczy P , Wen PY , Straube C , Pigorsch S , Wilkens JJ , Combs SE
Neuro-oncology Management During the COVID-19 Pandemic With a Focus on WHO Grade III and IV Gliomas
Neuro Oncol. 2020 May 5
PMID: 32369601    PMCID: PMC7239150    URL: https://www.ncbi.nlm.nih.gov/pubmed/32369601
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BACKGROUND: Because of the increased risk in cancer patients of developing complications caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), physicians have to balance the competing risks of the negative impact of the pandemic and the primary tumor. In this consensus statement, an international group of experts present mitigation strategies and treatment guidance for patients suffering from high grade gliomas (HGG) during the coronavirus disease 2019 (COVID-19) pandemic. METHOD / RESULTS: 16 international experts in the treatment of HGG contributed to this consensus-based practice recommendation including neuro-oncologists, neurosurgeons, radiation -oncologists and a medical physicist. Generally, treatment of neuro-oncological patients cannot be significantly delayed and initiating therapy should not be outweighed by COVID-19. We present detailed interdisciplinary treatment strategies for molecular subgroups in two pandemic scenarios, a scale-up phase and a crisis phase. CONCLUSION: This practice recommendation presents a pragmatic framework and consensus-based mitigation strategies for the treatment of HGG patients during the SARS-CoV-2 pandemic.
1523-5866 Bernhardt, Denise Wick, Wolfgang Weiss, Stephanie E Sahgal, Arjun Lo, Simon S Suh, John H Chang, Eric L Foote, Matthew Perry, James Meyer, Bernhard Vajkoczy, Peter Wen, Patrick Y Straube, Christoph Pigorsch, Steffi Wilkens, Jan J Combs, Stephanie E Journal Article England Neuro Oncol. 2020 May 5. pii: 5829911. doi: 10.1093/neuonc/noaa113.