FCCC Faculty Publications

Francescone R, Barbosa Vendramini-Costa D, Franco-Barraza J, Wagner J, Muir A, Lau AN, Gabitova L, Pazina T, Gupta S, Luong T, Rollins D, Malik R, Thapa RJ, Restifo D, Zhou Y, Cai KQ, Hensley HH, Tan Y, Kruger WD, Devarajan K, Balachandran S, Klein-Szanto AJ, Wang H, El-Deiry WS, Vander Heiden MG, Peri S, Campbell KS, Astsaturov I, Cukierman E. Netrin G1 promotes pancreatic tumorigenesis through cancer associated fibroblast driven nutritional support and immunosuppression. Cancer Discov. 2021 Feb;11(2) :446-479. PMC ID:PMC7858242.

Ye S, Sharipova D, Kozinova M, Klug L, D’Souza J, Belinsky MG, Johnson KJ, Einarson MB, Devarajan K, Zhou Y, Litwin S, Heinrich MC, DeMatteo R, von Mehren M, Duncan JS, Rink L. Identification of Wee1 as a target in combination with avapritinib for gastrointestinal stromal tumor treatment. JCI Insight. 2021 Jan 25;6(2) . PMC ID:PMC7934848.

O'Halloran EA, Board T, Lefton M, Devarajan K, Dotan E, Meyer J, Reddy SS. Predicting positive peritoneal cytology in pancreatic cancer. J Cancer Res Clin Oncol. 2021 Jan 3 .

Kurimchak AM, Kumar V, Herrera-Montávez C, Johnson KJ, Srivastava N, Devarajan K, Peri S, Cai KQ, Mantia-Smaldone GM, Duncan JS. Kinome Profiling of Primary Endometrial Tumors Using Multiplexed Inhibitor Beads and Mass Spectrometry Identifies SRPK1 As Candidate Therapeutic Target. Mol Cell Proteomics. 2020 Dec;19(12) :2068-2089. PMC ID:PMC7710141.

Dubey B, Jackson M, Zeigler-Johnson C, Devarajan K, Flores-Obando RE, McFarlane-Anderson N, Tulloch-Reid M, Aiken W, Kimbro K, Reed D, Kidd LR, Gibbs D, Kumar S, Ragin C. Interactive effect of TLR SNPs and exposure to sexually transmitted infections on prostate cancer risk in Jamaican men. Prostate. 2020 nov;80(15) :1365-1372. PMC ID:PMC7710572.

Spirko-Burns L, Devarajan K. Unified Methods for Feature Selection in Large-Scale Genomic Studies with Censored Survival Outcomes. Bioinformatics. 2020 Jun 1;36(11) :3409-3417. PMC ID:PMC7267818.

Jain R, Vijayvergia N, Devarajan K, Lewis B, Denlinger CS, Cohen SJ, Dotan E. Chemotherapy use and survival in older adults with metastatic pancreatic cancer in the combination therapy era. J Geriatr Oncol. 2020 May;11(4) :640-646. PMC ID:PMC7567610.

Ghatalia P, Gordetsky J, Kuo F, Dulaimi E, Cai KQ, Devarajan K, Bae S, Naik G, Chan TA, Uzzo R, Hakimi AA, Sonpavde G, Plimack E. Correction to: Prognostic impact of immune gene expression signature and tumor infiltrating immune cells in localized clear cell renal cell carcinoma. J Immunother Cancer. 2019 Oct 22;7(1) :273. PMC ID:PMC6806554.

Ghatalia P, Gordetsky J, Kuo F, Dulaimi E, Cai KQ, Devarajan K, Bae S, Naik G, Chan TA, Uzzo R, Hakimi AA, Sonpavde G, Plimack E. Prognostic impact of immune gene expression signature and tumor infiltrating immune cells in localized clear cell renal cell carcinoma. J Immunother Cancer. 2019 May 28;7(1) :139. PMC ID:PMC6540413.

Mancuso P, Tricarico R, Bhattacharjee V, Cosentino L, Kadariya Y, Jelinek J, Nicolas E, Einarson M, Beeharry N, Devarajan K, Katz RA, Dorjsuren DG, Sun H, Simeonov A, Giordano A, Testa JR, Davidson G, Davidson I, Larue L, Sobol RW, Yen TJ, Bellacosa A. Thymine DNA glycosylase as a novel target for melanoma. Oncogene. 2019 May;38(19) :3710-3728. PMC ID:PMC6563616.

Blackman E, Ashing K, Gibbs D, Kuo YM, Andrews A, Ramakodi M, Devarajan K, Bucci J, Jean-Louis G, Richards-Waritay O, Wilson B, Bowen C, Edi E, Tolbert V, Noumbissi R, Cabral DN, Oliver J, Roberts R, Tulloch-Reid M, Ragin C. The Cancer Prevention Project of Philadelphia: preliminary findings examining diversity among the African diaspora. Ethn Health. 2018 Nov 19 :1-17. PMC ID:PMC6526085.

Ebersole B, Soni RS, Moran K, Lango M, Devarajan K, Jamal N. The Influence of Occupation on Self-perceived Vocal Problems in Patients With Voice Complaints. J Voice. 2018 Nov;32(6) :673-680.

Chang WL, Jackson C, Riel S, Cooper HS, Devarajan K, Hensley HH, Zhou Y, Vanderveer LA, Nguyen MT, Clapper ML. Differential preventive activity of sulindac and atorvastatin in Apc(+/Min-FCCC)mice with or without colorectal adenomas. Gut. 2018 Jul;67(7) :1290-1298. PMC ID:PMC6031273.

Anari F, O'Neill J, Choi W, Chen DYT, Haseebuddin M, Kutikov A, Dulaimi E, Alpaugh RK, Devarajan K, Greenberg RE, Bilusic M, Wong YN, Viterbo R, Hoffman-Censits JH, Lallas CD, Trabulsi EJ, Smaldone M, Geynisman DM, Zibelman M, Lin J, Kelly WK, Uzzo R, McConkey D, Plimack ER. Neoadjuvant Dose-dense Gemcitabine and Cisplatin in Muscle-invasive Bladder Cancer: Results of a Phase 2 Trial. Eur Urol Oncol. 2018 May;1(1) :54-60. PMC ID:PMC6226048.

Ebersole B, Soni RS, Moran K, Lango M, Devarajan K, Jamal N. The Role of Occupational Voice Demand and Patient-Rated Impairment in Predicting Voice Therapy Adherence. J Voice. 2018 May;32(3) :325-331.

Mehrazin R, Dulaimi E, Uzzo RG, Devarjan K, Pei J, Smaldone MC, Kutikov A, Testa JR, Al-Saleem T. The correlation between gain of chromosome 8q and survival in patients with clear and papillary renal cell carcinoma. Ther Adv Urol. 2018 Jan;10(1) :3-10. PMC ID:PMC5761913.

Xu J, Cortellino S, Tricarico R, Chang WC, Scher G, Devarajan K, Slifker M, Moore R, Bassi MR, Caretti E, Clapper M, Cooper H, Bellacosa A. Thymine DNA Glycosylase (TDG) is involved in the pathogenesis of intestinal tumors with reduced APC expression. Oncotarget. 2017 Oct 27;8(52) :89988-89997. PMC ID:PMC5685726.

Dubey B, Jackson M, Zeigler-Johnson C, Devarajan K, Flores-Obando RE, McFarlane-Anderson N, Tulloch-Reid M, Aiken W, Kimbro K, Jones D, Kidd LR, Ragin C. Inflammation polymorphisms and prostate cancer risk in Jamaican men: Role of obesity/body size. Gene. 2017 Sep 10;636 :96-102. PMC ID:PMC5645041.

Jiang W, Dulaimi E, Devarajan K, Parsons T, Wang Q, O'Neill R, Solomides C, Peiper SC, Testa JR, Uzzo R, Yang H. Intratumoral heterogeneity analysis reveals hidden associations between protein expression losses and patient survival in clear cell renal cell carcinoma. Oncotarget. 2017 Jun 06;8(23) :37423-37434. PMC ID:PMC5514919.

Jiang Z, Slater CM, Zhou Y, Devarajan K, Ruth KJ, Li Y, Cai KQ, Daly M, Chen X. LincIN, a novel NF90-binding long non-coding RNA, is overexpressed in advanced breast tumors and involved in metastasis. Breast Cancer Res. 2017 May 30;19(1) :62. PMC ID:PMC5450112.

Peri S, Caretti E, Tricarico R, Devarajan K, Cheung M, Sementino E, Menges CW, Nicolas E, Vanderveer LA, Howard S, Conrad P, Crowell JA, Campbell KS, Ross EA, Godwin AK, Yeung AT, Clapper ML, Uzzo RG, Henske EP, Ricketts CJ, Vocke CD, Marston Linehan W, Testa JR, Bellacosa A, Kopelovich L, Knudson AG. Haploinsufficiency in tumor predisposition syndromes: Altered genomic transcription in morphologically normal cells heterozygous for VHL or TSC mutation. Oncotarget. 2017 Mar 14;8(11) :17628-17642. PMC ID:PMC5392274.

Ramakodi MP, Devarajan K, Blackman E, Gibbs D, Luce D, Deloumeaux J, Duflo S, Liu JC, Mehra R, Kulathinal RJ, Ragin CC. Integrative genomic analysis identifies ancestry-related expression quantitative trait loci on DNA polymerase beta and supports the association of genetic ancestry with survival disparities in head and neck squamous cell carcinoma. Cancer. 2017 Mar 01;123(5) :849-860. PMC ID:PMC5319896.

Ragin C, Liu JC, Jones G, Shoyele O, Sowunmi B, Kennett R, Gibbs D, Blackman E, Esan M, Brandwein MS, Devarajan K, Bussu F, Chernock R, Chien CY, Cohen MA, El-Mofty S, Suzuki M, D'Souza G, Funchain P, Eng C, Gollin SM, Hong A, Jung YS, Kruger M, Lewis J, Morbini P, Landolfo S, Ritta M, Straetmans J, Szarka K, Tachezy R, Worden FP, Nelson D, Gathere S, Taioli E. Prevalence of HPV infection in racial-ethnic subgroups of head and neck cancer patients. Carcinogenesis. 2017 Feb;38(2) :218-229. PMC ID:PMC7191086.

Franco-Barraza J, Francescone R, Luong T, Shah N, Madhani R, Cukierman G, Dulaimi E, Devarajan K, Egleston BL, Nicolas E, Katherine Alpaugh R, Malik R, Uzzo RG, Hoffman JP, Golemis EA, Cukierman E. Matrix-regulated integrin alphavbeta5 maintains alpha5beta1-dependent desmoplastic traits prognostic of neoplastic recurrence. Elife. 2017 Jan 31;6 . PMC ID:PMC5283834.

Zook P, Pathak HB, Belinsky MG, Gersz L, Devarajan K, Zhou Y, Godwin AK, von Mehren M, Rink L. Combination of Imatinib Mesylate and AKT Inhibitor Provides Synergistic Effects in Preclinical Study of Gastrointestinal Stromal Tumor. Clin Cancer Res. 2017 Jan 01;23(1) :171-180. PMC ID:PMC5203981.

Jiang W, Dulaimi E, Devarajan K, Parsons T, Wang Q, Liao L, Cho EA, O'Neill R, Solomides C, Peiper SC, Testa JR, Uzzo R, Yang H. Immunohistochemistry Successfully Uncovers Intratumoral Heterogeneity and Widespread Co-Losses of Chromatin Regulators in Clear Cell Renal Cell Carcinoma. PLoS One. 2016 Oct;11(10) :e0164554. PMC ID:PMC5072613.

Devarajan K, Cheung VC. A Quasi-Likelihood Approach to Nonnegative Matrix Factorization. Neural Comput. 2016 Aug;28(8) :1663-93. PMC ID:PMC5549860.

Duong-Ly KC, Devarajan K, Liang S, Horiuchi KY, Wang Y, Ma H, Peterson JR. Kinase Inhibitor Profiling Reveals Unexpected Opportunities to Inhibit Disease-Associated Mutant Kinases. Cell Rep. 2016 Feb 2;14(4) :772-81. PMC ID:PMC4740242.

Wang M, Devarajan K, Singal AG, Marrero JA, Dai J, Feng Z, Rinaudo JA, Srivastava S, Evans A, Hann HW, Lai Y, Yang H, Block TM, Mehta A. The Doylestown Algorithm: A Test to Improve the Performance of AFP in the Detection of Hepatocellular Carcinoma. Cancer Prev Res (Phila). 2016 Feb;9(2) :172-9. PMC ID:PMC4740237.

Toto JM, Chang EI, Agag R, Devarajan K, Patel SA, Topham NS. Improved operative efficiency of free fibula flap mandible reconstruction with patient-specific, computer-guided preoperative planning. Head Neck. 2015 Nov;37(11) :1660-1664.

Vijayvergia N, Dotan E, Devarajan K, Hatahet K, Rahman F, Ricco J, Lewis B, Gupta S, Cohen SJ. Patterns of care and outcomes of older versus younger patients with metastatic pancreatic cancer: A Fox Chase Cancer Center experience. J Geriatr Oncol. 2015 Nov;6(6) :454-61. PMC ID:PMC4921214.

Murphy CT, Devarajan K, Wang LS, Mehra R, Ridge JA, Fundakowski C, Galloway TJ. Pre-treatment tumor-specific growth rate as a temporal biomarker that predicts treatment failure and improves risk stratification for oropharyngeal cancer. Oral Oncol. 2015 Nov;51(11) :1034-40.

Tricarico R, Cortellino S, Riccio A, Jagmohan-Changur S, Van der Klift H, Wijnen J, Turner D, Ventura A, Rovella V, Percesepe A, Lucci-Cordisco E, Radice P, Bertario L, Pedroni M, Ponz de Leon M, Mancuso P, Devarajan K, Cai KQ, Klein-Szanto AJ, Neri G, Moller P, Viel A, Genuardi M, Fodde R, Bellacosa A. Involvement of MBD4 inactivation in mismatch repair-deficient tumorigenesis. Oncotarget. 2015 Oct 16;6(40) :42892-904. PMC ID:PMC4767479.

Zibelman M, Wong YN, Devarajan K, Malizzia L, Corrigan A, Olszanski AJ, Denlinger CS, Roethke SK, Tetzlaff CH, Plimack ER. Phase I study of the mTOR inhibitor ridaforolimus and the HDAC inhibitor vorinostat in advanced renal cell carcinoma and other solid tumors. Invest New Drugs. 2015 Oct;33(5) :1040-7. PMC ID:PMC4573837.

Devarajan K, Wang G, Ebrahimi N. A unified statistical approach to non-negative matrix factorization and probabilistic latent semantic indexing. Mach Learn. 2015 Apr 1;99(1) :137-163.

Chen KT, Devarajan K, Hoffman JP. Morbidity among long-term survivors after pancreatoduodenectomy for pancreatic adenocarcinoma. Ann Surg Oncol. 2015 Apr;22(4) :1185-9.

Cheung VCK, Devarajan K, Severini G, Turolla A, Bonato P, Ieee. Decomposing Time Series Data by a Non-negative Matrix Factorization Algorithm with Temporally Constrained Coefficients. 2015 37th Annual International Conference of the Ieee Engineering in Medicine and Biology Society. 2015 :3496-3499.

Fink LS, Beatty A, Devarajan K, Peri S, Peterson JR. Pharmacological Profiling of Kinase Dependency in Cell Lines across Triple-Negative Breast Cancer Subtypes. Mol Cancer Ther. 2015 Jan;14(1) :298-306. PMC ID:PMC4297247.

Dotan E, Devarajan K, D'Silva AJ, Beck A, Kloth DD, Cohen SJ, Denlinger C. Patterns of use and tolerance of anti-epidermal growth factor receptor antibodies in older adults with metastatic colorectal cancer. Clin Colorectal Cancer. 2014 Sep;13(3) :192-8.

Hensley H, Devarajan K, Johnson JR, Piwnica-Worms D, Godwin AK, von Mehren M, Rink L. Evaluating new therapies in gastrointestinal stromal tumor using in vivo molecular optical imaging. Cancer Biol Ther. 2014 Jul;15(7) :911-8. PMC ID:PMC4100992.

Patel SA, Sandberg LJ, Ranganath B, Devarajan K, Toto J, Topham NS. Impact of adjuvant chemotherapy on abdominal wall hernias and bulges after muscle-sparing free TRAM flaps for breast reconstruction. Ann Plast Surg. 2014 Jul;73(1) :62-7.

Freedman GM, Fowble BL, Li T, Hwang ES, Schechter N, Devarajan K, Anderson PR, Sigurdson ER, Goldstein LJ, Bleicher RJ. Risk of positive nonsentinel nodes in women with 1-2 positive sentinel nodes related to age and molecular subtype approximated by receptor status. Breast J. 2014 Jul-Aug;20(4) :358-63.

Gowrishankar B, Ibragimova I, Zhou Y, Slifker MJ, Devarajan K, Al-Saleem T, Uzzo RG, Cairns P. MicroRNA expression signatures of stage, grade, and progression in clear cell RCC. Cancer Biol Ther. 2014 Mar 1;15(3) :329-41. PMC ID:PMC3974834.

Chen KT, Devarajan K, Milestone BN, Cooper HS, Denlinger C, Cohen SJ, Meyer JE, Hoffman JP. Neoadjuvant chemoradiation and duration of chemotherapy before surgical resection for pancreatic cancer: does time interval between radiotherapy and surgery matter?. Ann Surg Oncol. 2014 Feb;21(2) :662-9.

Dames DN, Blackman E, Butler R, Taioli E, Eckstein S, Devarajan K, Griffith-Bowe A, Gomez P, Ragin C. High-Risk Cervical Human Papillomavirus Infections among Human Immunodeficiency Virus-Positive Women in the Bahamas. PLoS One. 2014 Jan 23;9(1) :e85429. PMC ID:PMC3900425.

Pape-Zambito D, Jiang Z, Wu H, Devarajan K, Slater CM, Cai KQ, Patchefsky A, Daly MB, Chen X. Identifying a Highly-Aggressive DCIS Subgroup by Studying Intra-Individual DCIS Heterogeneity among Invasive Breast Cancer Patients. PLoS One. 2014 ;9(6) :e100488.

Chen KT, Kim PD, Jones KA, Devarajan K, Patel BB, Hoffman JP, Ehya H, Huang M, Watson JC, Tokar JL, Yeung AT. Potential prognostic biomarkers of pancreatic cancer. Pancreas. 2014 Jan;43(1) :22-7. PMC ID:PMC3859961.

Wang MJ, Mehta A, Block TM, Marrero J, Di Bisceglie AM, Devarajan K. A comparison of statistical methods for the detection of hepatocellular carcinoma based on serum biomarkers and clinical variables. Bmc Medical Genomics. 2013 Nov;6 :S9. PMC ID:PMC 3980825.

Comunale MA, Wang MJ, Anbarasan N, Betesh L, Karabudak A, Moritz E, Devarajan K, Marrero J, Block TM, Mehta A. Total serum glycan analysis is superior to lectin-FLISA for the early detection of hepatocellular carcinoma. Proteomics Clinical Applications. 2013 Oct;7(9-10) :690-700.

Anastassiadis T, Duong-Ly KC, Deacon SW, Lafontant A, Ma H, Devarajan K, Dunbrack RL Jr, Wu J, Peterson JR. A highly selective dual insulin receptor (IR)/insulin-like growth factor 1 receptor (IGF-1R) inhibitor derived from an extracellular signal-regulated kinase (ERK) inhibitor. J Biol Chem. 2013 Sep 27;288(39) :28068-77. PMC ID:PMC3784719.

Sterious S, Simhan J, Uzzo RG, Gershman B, Li T, Devarajan K, Canter D, Walton J, Fogg R, Ginzburg S, Corcoran A, Smaldone MC, Kutikov A. Familiarity and self-reported compliance with American Urological Association best practice recommendations for use of thromboembolic prophylaxis among American Urological Association members. J Urol. 2013 Sep;190(3) :992-8.

Fernandez SV, Robertson FM, Pei JM, Aburto-Chumpitaz L, Mu ZM, Chu K, Alpaugh RK, Huang Y, Cao Y, Ye ZM, Cai KQ, Boley KM, Klein-Szanto AJ, Devarajan K, Addya S, Cristofanilli M. Inflammatory breast cancer (IBC): clues for targeted therapies. Breast Cancer Research and Treatment. 2013 Jul;140(1) :23-33.

Devarajan K, Ebrahirni N. On penalized likelihood estimation for a non-proportional hazards regression model. Statistics & Probability Letters. 2013 Jul;83(7) :1703-1710.

Miller SM, Hudson SV, Egleston BL, Manne S, Buzaglo JS, Devarajan K, Fleisher L, Millard J, Solarino N, Trinastic J, Meropol NJ. The relationships among knowledge, self-efficacy, preparedness, decisional conflict, and decisions to participate in a cancer clinical trial. Psychooncology. 2013 Mar;22(3) :481-9. PMC ID:PMC3374030.

Weinberg DS, Keenan E, Ruth K, Devarajan K, Rodoletz M, Bieber EJ. A randomized comparison of print and web communication on colorectal cancer screening. JAMA Intern Med. 2013 Jan 28;173(2) :122-9. PMC ID:PMC 3615476.

Peri S, Devarajan K, Yang DH, Knudson AG, Balachandran S. Meta-Analysis Identifies NF-kappaB as a Therapeutic Target in Renal Cancer. PLoS One. 2013 ;8(10) :e76746.

Zaorsky NG, Li TY, Devarajan K, Horwitz EM, Buyyounouski MK. Assessment of the American Joint Committee on Cancer Staging (Sixth and Seventh Editions) for Clinically Localized Prostate Cancer Treated With External Beam Radiotherapy and Comparison With the National Comprehensive Cancer Network Risk-Stratification Method. Cancer. 2012 Nov;118(22) :5535-5543. PMC ID:PMC3410044.

Gao C, Devarajan K, Zhou Y, Slater CM, Daly MB, Chen X. Identifying breast cancer risk loci by global differential allele-specific expression (DASE) analysis in mammary epithelial transcriptome. BMC Genomics. 2012 Oct 30;13(1) :570. PMC ID:PMCID3532379.

Fleisher L, Kandadai V, Keenan E, Miller SM, Devarajan K, Ruth KJ, Rodoletz M, Bieber EJ, Weinberg DS. Build it, and will they come? Unexpected findings from a study on a web-based intervention to improve colorectal cancer screening. J Health Commun. 2012 Jan;17(1) :41-53. PMC ID:PMC3257821.

Jiang Z, Zhou Y, Devarajan K, Slater CM, Daly MB, Chen X. Identifying putative breast cancer-associated long intergenic non-coding RNA loci by high density SNP array analysis. Front Genet. 2012 ;3 :299. PMC ID:PMC3528021.

Anastassiadis T, Deacon SW, Devarajan K, Ma HC, Peterson JR. Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity. Nature Biotechnology. 2011 Nov;29(11) :1039-U117. PMC ID:PMC3230241.

Clapper ML, Hensley HH, Chang WC, Devarajan K, Nguyen MT, Cooper HS. Detection of colorectal adenomas using a bioactivatable probe specific for matrix metalloproteinase activity. Neoplasia. 2011 Aug;13(8) :685-91. PMC ID:PMC3156659.

Sasaroli D, Gimotty PA, Pathak HB, Hammond R, Kougioumtzidou E, Katsaros D, Buckanovich R, Devarajan K, Sandaltzopoulos R, Godwin AK, Scholler N, Coukos G, Stellani P VP. Novel surface targets and serum biomarkers from the ovarian cancer vasculature. Cancer Biology & Therapy. 2011 Aug;12(3) :169-180. PMC ID:PMC3230481.

Cortellino S, Xu J, Sannai M, Moore R, Caretti E, Cigliano A, Le Coz M, Devarajan K, Wessels A, Soprano D, Abramowitz LK, Bartolomei MS, Rambow F, Bassi MR, Bruno T, Fanciulli M, Renner C, Klein-Szanto AJ, Matsumoto Y, Kobi D, Davidson I, Alberti C, Larue L, Bellacosa A. Thymine DNA Glycosylase Is Essential for Active DNA Demethylation by Linked Deamination-Base Excision Repair. Cell. 2011 Jul 8;146(1) :67-79.

Makhlin I, Zhang J, Long CJ, Devarajan K, Zhou Y, Klein-Szanto AJ, Huang M, Chernoff J, Boorjian SA. The mTOR pathway affects proliferation and chemosensitivity of urothelial carcinoma cells and is upregulated in a subset of human bladder cancers. Bju International. 2011 Jul;108(2B) :E84-E90. PMC ID:PMC3116980.

Frank AK, Leu JIJ, Zhou Y, Devarajan K, Nedelko T, Klein-Szanto A, Hollstein M, Murphy ME. The Codon 72 Polymorphism of p53 Regulates Interaction with NF-kappa B and Transactivation of Genes Involved in Immunity and Inflammation. Molecular and Cellular Biology. 2011 Mar;31(6) :1201-1213. PMC ID:PMC3067895.

Devarajan K, Ebrahimi N. A semi-parametric generalization of the Cox proportional hazards regression model: Inference and Applications. Comput Stat Data Anal. 2011 Jan 1;55(1) :667-676. PMC ID:PMC2976538.

Gupta V, Bassi DE, Simons JD, Devarajan K, Al-Saleem T, Uzzo RG, Cukierman E. Elevated expression of stromal palladin predicts poor clinical outcome in renal cell carcinoma. PLoS One. 2011 ;6(6) :e21494. PMC ID:PMC3125241.

Shatalova EG, Klein-Szanto AJ, Devarajan K, Cukierman E, Clapper ML. Estrogen and Cytochrome P450 1B1 Contribute to Both Early- and Late-Stage Head and Neck Carcinogenesis. Cancer Prev Res (Phila). 2011 Jan;4(1) :107-15. PMC ID:PMC3043603.

Meireles SI, Esteves GH, Hirata R Jr, Peri S, Devarajan K, Slifker M, Mosier SL, Peng J, Vadhanam MV, Hurst HE, Neves EJ, Reis LF, Gairola CG, Gupta RC, Clapper ML. Early changes in gene expression induced by tobacco smoke: Evidence for the importance of estrogen within lung tissue. Cancer Prev Res (Phila). 2010 Jun;3(6) :707-17. PMC ID:PMC2896420.

Devarajan K, Zhou Y, Chachra N, Ebrahimi N. A supervised approach for predicting patient survival with gene expression data. Proc IEEE Int Symp Bioinformatics Bioeng. 2010 ;2010(5521718) :26-31. PMC ID:PMC2941901.

Bellacosa A, Godwin AK, Peri S, Devarajan K, Caretti E, Vanderveer L, Bove B, Slater C, Zhou Y, Daly M, Howard S, Campbell KS, Nicolas E, Yeung AT, Clapper ML, Crowell JA, Lynch HT, Ross E, Kopelovich L, Knudson AG. Altered gene expression in morphologically normal epithelial cells from heterozygous carriers of BRCA1 or BRCA2 mutations. Cancer Prev Res (Phila Pa). 2010 Jan;3(1) :48-61. PMC ID:PMC2804937.

Astsaturov I, Ratushny V, Sukhanova A, Einarson MB, Bagnyukova T, Zhou Y, Devarajan K, Silverman JS, Tikhmyanova N, Skobeleva N, Pecherskaya A, Nasto RE, Sharma C, Jablonski SA, Serebriiskii IG, Weiner LM, Golemis EA. Synthetic lethal screen of an EGFR-centered network to improve targeted therapies. Sci Signal. 2010 ;3(140) :ra67. PMC ID:PMC2950064.

Schilder RJ, Pathak HB, Lokshin AE, Holloway RW, Alvarez RD, Aghajanian C, Min H, Devarajan K, Ross E, Drescher CW, Godwin AK. Phase II trial of single agent cetuximab in patients with persistent or recurrent epithelial ovarian or primary peritoneal carcinoma with the potential for dose escalation to rash. Gynecol Oncol. 2009 Apr;113(1) :21-7. PMC ID:PMC 2741166.

Fang CY, Cherry C, Devarajan K, Li TY, Malick J, Daly MB. A prospective study of quality of life among women undergoing risk-reducing salpingo-oophorectomy versus gynecologic screening for ovarian cancer. Gynecologic Oncology. 2009 Mar;112(3) :594-600. PMC ID:PMC2697574.

Hensley HH, Merkel CE, Chang WC, Devarajan K, Cooper HS, Clapper ML. Endoscopic imaging and size estimation of colorectal adenomas in the multiple intestinal neoplasia mouse. Gastrointest Endosc. 2009 Mar;69(3 Suppl) :742-9. PMC ID:PMC2821747.

Devarajan K, Ebrahimi N. Testing for Covariate Effect in the Cox Proportional Hazards Regression Model. Commun Stat Theory Methods. 2009 Jan 1;38(14) :2333-2347. PMC ID:PMC2802211.

Clapper ML, Gary MA, Coudry RA, Litwin S, Chang WC, Devarajan K, Lubet RA, Cooper HS. 5-aminosalicylic acid inhibits colitis-associated colorectal dysplasias in the mouse model of azoxymethane/dextran sulfate sodium-induced colitis. Inflamm Bowel Dis. 2008 Oct;14(10) :1341-7.

Shimizu I, Jellinek NJ, Dufresne RG, Li T, Devarajan K, Perlis C. Multiple antithrombotic agents increase the risk of postoperative hemorrhage in dermatologic surgery. Journal of the American Academy of Dermatology. 2008 May;58(5) :810-816.

Caretti E, Devarajan K, Coudry R, Ross E, Clapper ML, Cooper HS, Bellacosa A. Comparison of RNA amplification methods and chip platforms for microarray analysis of samples processed by laser capture microdissection. J Cell Biochem. 2008 Feb 1;103(2) :556-63.

Devarajan K. Nonnegative matrix factorization: an analytical and interpretive tool in computational biology. PLoS Comput Biol. 2008 ;4(7) :e1000029. PMC ID:PMC2447881.

Rennefahrt UE, Deacon SW, Parker SA, Devarajan K, Beeser A, Chernoff J, Knapp S, Turk BE, Peterson JR. Specificity profiling of Pak kinases allows identification of novel phosphorylation sites. J Biol Chem. 2007 May 25;282(21) :15667-78.

Altomare DA, Vaslet CA, Skele KL, De Rienzo A, Devarajan K, Jhanwar SC, McClatchey AI, Kane AB, Testa JR. A mouse model recapitulating molecular features of human mesothelioma. Cancer Research. 2005 Sep 15;65(18) :8090-8095.

Manne SL, Ostroff JS, Winkel G, Fox K, Grana G, Miller E, Ross S, Frazier T, Buyyounouski MK, Hanlon AL, Eisenberg DF, Horwitz EM, Feigenberg SJ, Uzzo RG, Pollack A, Morrow M, Chen JQ, Yager JD, Russo J, Bassi DE, Fu J, Lopez de Cicco R, Klein-Szanto AJ, Devlin J, Sherman E, Altomare DA, Vaslet CA, Skele KL, De Rienzo A, Devarajan K, Jhanwar SC, McClatchey AI, Kane AB, Testa JR, Murphy ME, Langer CJ, Mehta MP, Viterbo R, Greenberg RE, Al-Saleem T, Canutescu AA, Dunbrack RL Jr, Serebriiskii IG, Fang R, Latypova E, Hopkins R, Vinson C, Joung JK, Golemis EA. Couple-focused group intervention for women with early stage breast cancer. . J Consult Clin Psychol. 2005 Aug May Sep 15 Sep 1 Jun 15 Jun;73(4) :634-46..

Devarajan K (84 publications)