FCCC Faculty Publications

Price RA Jr, Jin L, Meyer J, Chen L, Lin T, Eldib A, Chen X, Liu J, Veltchev I, Wang L, Ma C. Practical Clinical Implementation of the Special Physics Consultation Process in the Re-irradiation Environment. Adv Radiat Oncol. 2021 Jan-Feb;6(1) :100594. PMC ID:PMC7811122.

Song Z, Wei W, Xiao W, Al-Saleem ED, Nejati R, Chen L, Yin J, Fabrizio J, Petrus MN, Waldmann TA, Yang Y. Essential role of the linear ubiquitin chain assembly complex and TAK1 kinase in A20 mutant Hodgkin lymphoma. Proc Natl Acad Sci U S A. 2020 Nov 17;117(46) :28980-28991. PMC ID:PMC7682429.

Shan G, Hu W, Chen L, Price RA, Ma CC. Dosimetric evaluation of image-guided radiation therapy for prostate cancer. Med Dosim. 2020 Oct 2 .

Panetta J, Cvetkovic D, Chen X, Chen L, Ma CC. Radiodynamic therapy using 15-MV radiation combined with 5-aminolevulinic acid and carbamide peroxide for prostate cancer <i>in vivo</i>. Phys Med Biol. 2020 Aug 19;65(16) :165008.

Wei W, Lin Y, Song Z, Xiao W, Chen L, Yin J, Zhou Y, Barta SK, Petrus M, Waldmann TA, Yang Y. A20 and RBX1 regulate brentuximab vedotin sensitivity in Hodgkin Lymphoma models. Clin Cancer Res. 2020 Aug 1;26(15) :4093-4106. PMC ID:PMC7549381.

Xu Q, Tong X, Lin M, Chen X, ElDib A, Lin T, Chen L, Ma CC. Time and frequency to observe fiducial markers in MLC-modulated fields during prostate IMRT/VMAT beam delivery. Phys Med. 2020 Jul 14;76 :142-149. PMC ID:PMC7528608.

Chen SJ, Bao L, Keefer K, Shanmughapriya S, Chen L, Lee J, Wang J, Zhang XQ, Hirschler-Laszkiewicz I, Merali S, Merali C, Imamura Y, Dovat S, Madesh M, Cheung JY, Wang HG, Miller BA. Transient receptor potential ion channel TRPM2 promotes AML proliferation and survival through modulation of mitochondrial function, ROS, and autophagy. Cell Death Dis. 2020 Apr 20;11(4) :247. PMC ID:PMC7170900.

Liu J, Lin T, Fan J, Chen L, Price R, Ma CC. Evaluation of the combined use of two different respiratory monitoring systems for 4D CT simulation and gated treatment. J Appl Clin Med Phys. 2018 Sep;19(5) :666-675. PMC ID:PMC6123155.

Li PD, Liu Z, Cheng TT, Luo WG, Yao J, Chen J, Zou ZW, Chen LL, Ma C, Dai XF. Redox-dependent modulation of metformin contributes to enhanced sensitivity of esophageal squamous cell carcinoma to cisplatin. Oncotarget. 2017 Sep 22;8(37) :62057-62068. PMC ID:PMC5617486.

Ribas A, Dummer R, Puzanov I, VanderWalde A, Andtbacka RHI, Michielin O, Olszanski AJ, Malvehy J, Cebon J, Fernandez E, Kirkwood JM, Gajewski TF, Chen L, Gorski KS, Anderson AA, Diede SJ, Lassman ME, Gansert J, Hodi FS, Long GV. Oncolytic Virotherapy Promotes Intratumoral T Cell Infiltration and Improves Anti-PD-1 Immunotherapy. Cell. 2017 Sep 07;170(6) :1109-1119.e10.

Scannell Bryan M, Argos M, Andrulis IL, Hopper JL, Chang-Claude J, Malone K, John EM, Gammon MD, Daly M, Terry MB, Buys SS, Huo D, Olopade O, Genkinger JM, Jasmine F, Kibriya MG, Chen L, Ahsan H. Limited influence of germline genetic variation on all-cause mortality in women with early onset breast cancer: evidence from gene-based tests, single-marker regression, and whole-genome prediction. Breast Cancer Res Treat. 2017 Aug;164(3) :707-717. PMC ID:PMC5510603.

Bryan MS, Argos M, Andrulis IL, Hopper JL, Chang-Claude J, Malone K, John EM, Gammon MD, Daly M, Terry MB, Buys SS, Huo DZ, Olopade O, Genkinger JM, Jasmine F, Kibriya MG, Chen L, Ahsan H. Limited influence of germline genetic variation on all-cause mortality in women with early onset breast cancer: evidence from gene-based tests, single-marker regression, and whole-genome prediction. Breast Cancer Res Treat. 2017 Aug;164(3) :707-717. PMC ID:PMC5510603.

Meyer JE, Finnberg NK, Chen L, Cvetkovic D, Wang B, Zhou L, Dong Y, Hallman MA, Ma CC, El-Deiry WS. Tissue TGF-beta expression following conventional radiotherapy and pulsed low-dose-rate radiation. Cell Cycle. 2017 Jun 18;16(12) :1171-1174. PMC ID:PMC5499842.

Liu T, Kan XF, Ma C, Chen LL, Cheng TT, Zou ZW, Li Y, Cao FJ, Zhang WJ, Yao J, Li PD. GPX2 overexpression indicates poor prognosis in patients with hepatocellular carcinoma. Tumour Biol. 2017 Jun;39(6) :1010428317700410.

Li PD, Hu JL, Ma C, Ma H, Yao J, Chen LL, Chen J, Cheng TT, Yang KY, Wu G, Zhang WJ, Cao RB. Upregulation of the long non-coding RNA PVT1 promotes esophageal squamous cell carcinoma progression by acting as a molecular sponge of miR-203 and LASP1. Oncotarget. 2017 May 23;8(21) :34164-34176. PMC ID:PMC5470958.

Peng S, Zhou P, He W, Liao M, Chen L, Ma CM. Treatment of hepatic tumors by thermal versus mechanical effects of pulsed high intensity focused ultrasound in vivo. Phys Med Biol. 2016 Sep 21;61(18) :6754-6769.

Zou ZW, Ma C, Medoro L, Chen L, Wang B, Gupta R, Liu T, Yang XZ, Chen TT, Wang RZ, Zhang WJ, Li PD. LncRNA ANRIL is up-regulated in nasopharyngeal carcinoma and promotes the cancer progression via increasing proliferation, reprograming cell glucose metabolism and inducing side-population stem-like cancer cells. Oncotarget. 2016 Sep 20;7(38) :61741-61754. PMC ID:PMC5308687.

Fan J, Lin T, Jin L, Chen L, Veltchev I, Wang L, Eldib A, Chibani O, Wang B, Xu Q, Price R, Ma C. MO-FG-CAMPUS-JeP3-05: Evaluation of 4D CT-On-Rails Target Localization Methods for Free Breathing Liver Stereotactic Body Radiotherapy (SBRT). Med Phys. 2016 Jun;43(6) :3727.

Chen L, Cvetkovic D, Gupta R, Wang B, Ma C. SU-E-J-01: MR Guided Pulsed Focused Ultrasound Mediated Targeted Chemotherapeutic-Agent Delivery in Management of Prostate Cancer. Med Phys. 2015 Jun;42(6) :3263.

Eldib A, Chibani O, Jin L, Li J, Lin M, Chen L, Lin T, Ma C. SU-E-T-262: Development of An In-House Forward Planning System for Conformal Arc Therapy. Med Phys. 2015 Jun;42(6) :3393.

Ma C, Eldib A, Li C, Chibani O, Mora G, Li J, Chen L. SU-E-T-335: Dosimetric Investigation of An Advanced Rotating Gamma Ray System for Imaged Guided Radiation Therapy. Med Phys. 2015 Jun;42(6) :3410.

Tong X, Luo F, Liu Y, Zhang W, Xu Q, Zhang T, Li J, Chen L, Ma C. SU-E-T-620: Planning and Dosimetry for Pulsed Low Dose Rate RT for Recurrent Lung, Spine, GYN and Head and Neck Cancers. Med Phys. 2015 Jun;42(6) :3479.

Wang B, Cvetkovic D, Wang C, Chen L, Ma C. SU-E-T-668: Radiosensitizing Effect of Bosutinib On Prostate and Colon Cancers: A Pilot in Vitro Study. Med Phys. 2015 Jun;42(6) :3490.

Cvetkovic D, Wang B, Chen L, Ma C. SU-E-T-715: Subacute Effects of Pulsed Low Dose Rate Radiotherapy and Conventional Radiotherapy On Normal Mouse Tissues. Med Phys. 2015 Jun;42(6) :3501.

Ma C, Chibani O, Mora G, Li J, Chen L. SU-E-T-94: An Advanced Rotating Gamma Ray System for Stereotactic Radiosurgery. Med Phys. 2015 Jun;42(6) :3352.

Gupta R, Cvetkovic D, Wang B, Ma C, Chen L. SU-E-U-04: Evaluation of Normal Tissue Toxicity of Drug-Loaded Nanodroplets Used for Treating Prostate Cancer with MR-Guided Focused-Ultrasound. Med Phys. 2015 Jun;42(6) :3241.

Chen L. TU-CD-210-03: The Role of Pulsed Focused Ultrasound in Cancer Therapy. Medical Physics. 2015 Jun;42(6Part33) :3613-3613.

Chen L, Cvetkovic D, Gupta R, Wang B, Ma C. TU-CD-210-05: A Drug Delivery Technique Employing Pulsed Focused Ultrasound for Prostate Cancer Therapy. Med Phys. 2015 Jun;42(6) :3613.

Zhang P, Wang B, Chen X, Cvetkovic D, Chen L, Lang J, Ma CM. Local Tumor Control and Normal Tissue Toxicity of Pulsed Low-Dose Rate Radiotherapy for Recurrent Lung Cancer: An In Vivo Animal Study. Dose Response. 2015 Apr-Jun;13(2) :1559325815588507. PMC ID:PMC4674173.

Tong X, Chen X, Li J, Xu Q, Lin MH, Chen LL, Price RA, Ma CM. Intrafractional prostate motion during external beam radiotherapy monitored by a real-time target localization system. J Appl Clin Med Phys. 2015 Mar 08;16(2) :51-61. PMC ID:PMC5690091.

Dai X, Zhao Y, Liang Z, Dassarath M, Wang L, Jin L, Chen L, Dong J, Price RA, Ma CM. Volumetric-modulated arc therapy for oropharyngeal carcinoma: a dosimetric and delivery efficiency comparison with static-field IMRT. Phys Med. 2015 Feb;31(1) :54-9. PMC ID:PMC4282814.

Ma CM, Chen X, Cvetkovic D, Chen L. An in-vivo investigation of the therapeutic effect of pulsed focused ultrasound on tumor growth. Med Phys. 2014 Dec;41(12) :122901.

Li J, Lang J, Wang P, Kang S, Lin MH, Chen X, Chen F, Guo M, Chen L, Ma CMC. Intensity-modulated radiation therapy for pancreatic and prostate cancer using pulsed low-dose rate delivery techniques. Medical Dosimetry. 2014 Winter;39(4) :330-336.

Kang S, Lang J, Wang P, Li J, Lin M, Chen X, Guo M, Chen F, Chen L, Ma CM. Optimization strategies for pulsed low-dose-rate IMRT of recurrent lung and head and neck cancers. J Appl Clin Med Phys. 2014 May 8;15(3) :4661. PMC ID:PMC5711051.

Dong B, Duan X, Chow HY, Chen L, Lu H, Wu W, Hauck B, Wright F, Kapranov P, Xiao W. Proteomics Analysis of Co-Purifying Cellular Proteins Associated with rAAV Vectors. PLoS One. 2014 ;9(2) :e86453. PMC ID:PMC3911921.

Ma CM, Lin MH, Dai XF, Koren S, Klayton T, Wang L, Li JS, Chen L, Price RA. Investigation of pulsed low dose rate radiotherapy using dynamic arc delivery techniques. Phys Med Biol. 2012 Jul 21;57(14) :4613-26.

Hossain M, Schirmer T, Richardson T, Chen LL, Buyyounouski MK, Ma CM. Effect of Gold Marker Seeds on Magnetic Resonance Spectroscopy of the Prostate. International Journal of Radiation Oncology Biology Physics. 2012 May;83(1) :451-458.

Chen XM, Cvetkovic D, Ma CM, Chen LL. Quantitative study of focused ultrasound enhanced doxorubicin delivery to prostate tumor in vivo with MRI guidance. Medical Physics. 2012 May;39(5) :2780-2786.

Mu Z, Ma CM, Chen X, Cvetkovic D, Pollack A, Chen L. MR-guided pulsed high intensity focused ultrasound enhancement of docetaxel combined with radiotherapy for prostate cancer treatment. Phys Med Biol. 2012 Jan 4;57(2) :535-545.

Wang L, Feigenberg S, Fan J, Jin L, Turaka A, Chen L, Ma CM. Target repositional accuracy and PTV margin verification using three-dimensional cone-beam computed tomography (CBCT) in stereotactic body radiotherapy (SBRT) of lung cancers. J Appl Clin Med Phys. 2012 ;13(2) :3708.

Chen LL, Mu ZM, Hachem P, Ma CM, Wallentine A, Pollack A. MR-guided focused ultrasound: enhancement of intratumoral uptake of H-3 -docetaxel in vivo. Physics in Medicine and Biology. 2010 Dec;55(24) :7399-7410.

Li JS, Lin T, Chen LL, Price RA, Ma CM. Uncertainties in IMRT dosimetry. Medical Physics. 2010 Jun;37(6) :2491-2500.

Chen LL, Paskalev K, Xu X, Zhu J, Wang L, Price RA, Hu W, Feigenberg SJ, Horwitz EM, Pollack A, Ma CMC. Rectal dose variation during the course of image-guided radiation therapy of prostate cancer. Radiotherapy and Oncology. 2010 May;95(2) :198-202.

Yang J, Ma C, Wang L, Chen LL, Li JS. Effect of collimator and couch angle change on breast IMRT dose distributions. Journal of Applied Clinical Medical Physics. 2009 ;10(4) :55-63.

Jin L, Ma CM, Fan J, Eldib A, Price RA, Chen L, Wang L, Chi Z, Xu Q, Sherif M, Li JS. Dosimetric verification of modulated electron radiotherapy delivered using a photon multileaf collimator for intact breasts. Phys Med Biol. 2008 Nov 7;53(21) :6009-25.

Breen MS, Breen M, Butts K, Chen LL, Saidel GM, Wilson DL. MRI-guided thermal ablation therapy: Model and parameter estimates to predict cell death from MR thermometry images. Annals of Biomedical Engineering. 2007 Aug;35(8) :1391-1403.

Chen LL, Nguyen TB, Jones E, Chen ZQ, Luo W, Wang L, Price RA, Pollack A, Ma CMC. Magnetic resonance-based treatment planning for prostate intensity-modulated radiotherapy: Creation of digitally reconstructed radiographs. International Journal of Radiation Oncology Biology Physics. 2007 Jul;68(3) :903-911.

Wang L, Feigenberg S, Chen L, Pasklev K, Ma CC. Benefit of three-dimensional image-guided stereotactic localization in the hypofractionated treatment of lung cancer. Int J Radiat Oncol Biol Phys. 2006 Nov 1;66(3) :738-47.

Luo W, Li JS, Price RA, Chen LL, Yang J, Fan JJ, Chen ZQ, McNeeley S, Xu X, Ma CM. Monte Carlo based IMRT dose verification using MLC log files and R/V outputs. MEDICAL PHYSICS. 2006 Jul;33(7) :2557-2564.

Fan J, Li J, Chen L, Stathakis S, Luo W, Du Plessis F, Xiong W, Yang J, Ma CM. A practical Monte Carlo MU verification tool for IMRT quality assurance. Phys Med Biol. 2006 May 21;51(10) :2503-15.

Chen Z, Ma CM, Paskalev K, Li J, Yang J, Richardson T, Palacio L, Xu X, Chen L. Investigation of MR image distortion for radiotherapy treatment planning of prostate cancer. PHYSICS IN MEDICINE AND BIOLOGY. 2006 Mar;51(6) :1393-1403.

Wang L, Li JS, Paskalev K, Hoban P, Luo W, Chen LL, McNeeley S, Price R, Ma C. Commissioning and quality assurance of a commercial stereotactic treatment-planning system for extracranial IMRT. Journal of Applied Clinical Medical Physics. 2006 ;7(1) :21-34.

Wang L, Hoban P, Paskalev K, Yang J, Li JS, Chen LL, Xiong WJ, Ma CCM. Dosimetric advantage and clinical implication of a micro-multileaf collimator in the treatment of prostate with intensity-modulated radiotherapy. MEDICAL DOSIMETRY. 2005 Sum;30(2) :97-103.

Yang J, Li J, Chen L, Price R, McNeeley S, Qin L, Wang L, Xiong W, Ma CM. Dosimetric verification of IMRT treatment planning using Monte Carlo simulations for prostate cancer. Physics in Medicine and Biology. 2005 Sp. Iss. SI MAR 7;50(5) :869-878.

Chen L, Price RA, Nguyen TB, Wang L, Li JS, Qin L, Ding M, Palacio E, Ma CM, Pollack A. Dosimetric evaluation of MRI-based treatment planning for prostate cancer. Physics in Medicine and Biology. 2004 Nov 21;49(22) :5157-5170.

Chen L, Price RA Jr, Wang L, Li J, Qin L, McNeeley S, Ma CM, Freedman GM, Pollack A. MRI-based treatment planning for radiotherapy: dosimetric verification for prostate IMRT. International Journal of Radiation Oncology, Biology, Physics. 2004 Oct 1;60(2) :636-47.

Li JS, Freedman GM, Price R, Wang L, Anderson P, Chen L, Xiong W, Yang J, Pollack A, Ma CM. Clinical implementation of intensity-modulated tangential beam irradiation for breast cancer. Medical Physics. 2004 May;31(5) :1023-1031.

Ma CM, Price RA, Li JS, Chen L, Wang L, Fourkal E, Qin L, Yang J. Monitor unit calculation for Monte Carlo treatment planning. Physics in Medicine and Biology. 2004 May;49(9) :1671-1687.

Xiong W, Li J, Chen L, Price RA, Freedman G, Ding M, Qin L, Yang J, Ma CM. Optimization of combined electron and photon beams for breast cancer. Physics in Medicine and Biology. 2004 May;49(10) :1973-1989.

Wang L, Movsas B, Jacob R, Fourkal E, Chen L, Price R, Feigenberg S, Konski A, Pollack A, Ma C. Stereotactic IMRT for prostate cancer: dosimetric impact of multileaf collimator leaf width in the treatment of prostate cancer with IMRT. Journal of Applied Clinical Medical Physics. 2004 ;5(2) :29-41.

Wang L, Jacob R, Chen L, Ma C, Movsas B, Feigenberg S, Konski A. Stereotactic IMRT for prostate cancer: setup accuracy of a new stereotactic body localization system. Journal of Applied Clinical Medical Physics. 2004 ;5(2) :18-28.

Ma CM, Price R, McNeeley S, Chen L, Li JS, Wang L, Ding M, Fourkal E, Qin L. Clinical implementation and quality assurance for intensity modulated radiation therapy. Standards and Codes of Practice in Medical Radiation Dosimetry, Proceedings of an International Symposium, Vienna, Austria, Nov. 25-28, 2002. 2003 ;2 :369-380.

Butts K, Daniel BL, Chen L, Bouley DM, Wansapura J, Maier SE, Dumoulin C, Watkins R. Diffusion-weighted MRI after cryosurgery of the canine prostate. Magnetic resonance imaging. J Magn Reson Imaging. 2003 Jan;17(1) :131-5.

Chen L, Wansapura JP, Heit G, Butts K. Study of laser ablation in the in vivo rabbit brain with MR thermometry. J Magn Reson Imaging. 2002 Aug;16(2) :147-52.

Ma CM, Pawlicki T, Li JS, Deng J, Lee MC, Kapur A, Price RA, McNeeley S, Chen L, Fourkal E, Ding M. Accurate dosimetry for intensity modulated radiation therapy. Recent developments in accurate radiation dosimetry. 2002 :249-267.

Ma CM, Price RA, McNeeley S, Chen L. Clinical implementation and quality assurance for intensity modulated radiation therapy. Proceedings of the International Symposium on Standards and Codes of Practice in Medical Radiation Dosimetry. 2002 .

Chen L (66 publications)