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David Wiest

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Center AffiliationsBlood Cell Development and Function

Publications (94) (print view)

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Fahl SP, Coffey F, Kain L, Zarin P, Dunbrack RL, Teyton L, Zuniga-Pflucker JC, Kappes DJ, Wiest DL. Role of a selecting ligand in shaping the murine gammadelta-TCR repertoire. Proc Natl Acad Sci U S A. 2018 Feb 20;115(8):1889-94.   PMCID: PMC5828614
Fahl SP, Wiest DL. Reply to Chien: Clarification of the effect of ligand on gammadelta-TCR repertoire selection. Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):E3607-e3608.   PMCID: PMC5910880
Zarin P, In TS, Chen EL, Singh J, Wong GW, Mohtashami M, Wiest DL, Anderson MK, Zuniga-Pflucker JC. Integration of T Cell Receptor, Notch and Cytokine Signals Programs in Mouse gammadelta T Cell Effector Differentiation. Immunology and cell biology. 2018 May 13;.
In TS, Trotman-Grant A, Fahl S, Chen EL, Zarin P, Moore AJ, Wiest DL, Zuniga-Pflucker JC, Anderson MK. HEB is required for the specification of fetal IL-17-producing gammadelta T cells. Nat Commun. 2017 Dec 08;8(1):2004.   PMCID: PMC5722817
Isoda T, Moore AJ, He Z, Chandra V, Aida M, Denholtz M, Piet van Hamburg J, Fisch KM, Chang AN, Fahl SP, Wiest DL, Murre C. Non-coding Transcription Instructs Chromatin Folding and Compartmentalization to Dictate Enhancer-Promoter Communication and T Cell Fate. Cell. 2017 Sep 21;171(1):103-119e18.   PMCID: PMC5621651
Somech R, Lev A, Lee YN, Simon AJ, Barel O, Schiby G, Avivi C, Barshack I, Rhodes M, Yin J, Wang M, Yang Y, Rhodes J, Marcus N, Garty BZ, Stein J, Amariglio N, Rechavi G, Wiest DL, Zhang Y. Disruption of Thrombocyte and T Lymphocyte Development by a Mutation in ARPC1B. J Immunol. 2017 Nov 10;199(12):4036-45.   PMCID: PMC5726601
Tan Y, Sementino E, Xu J, Pei J, Liu Z, Ito TK, Cai KQ, Peri S, Klein-Szanto AJ, Wiest DL, Testa JR. The homeoprotein Dlx5 drives murine T-cell lymphomagenesis by directly transactivating Notch and upregulating Akt signaling. Oncotarget. 2017 Feb 28;8(9):14941-56.   PMCID: PMC5362456
Tan Y, Sementino E, Xu J, Pei J, Liu Z, Ito TK, Cai KQ, Peri S, Klein-Szanto AJ, Wiest DL, Testa JR. The homeoprotein Dlx5 drives murine T-cell lymphomagenesis by directly transactivating Notch and upregulating Akt signaling. Oncotarget. 2017 Jan 21;.
Wiest DL. THEMIS-tery is solved. Nature immunology. 2017 Mar 22;18(4):368-70.
Zhang Y, O'Leary MN, Peri S, Wang M, Zha J, Melov S, Kappes DJ, Feng Q, Rhodes J, Amieux PS, Morris DR, Kennedy BK, Wiest DL. Ribosomal Proteins Rpl22 and Rpl22l1 Control Morphogenesis by Regulating Pre-mRNA Splicing. Cell Rep. 2017 Jan 10;18(2):545-56.   PMCID: PMC5234864
Zhang Y, O'Leary MN, Peri S, Wang M, Zha J, Melov S, Kappes DJ, Feng Q, Rhodes J, Amieux PS, Morris DR, Kennedy BK, Wiest DL. Ribosomal Proteins Rpl22 and Rpl22l1 Control Morphogenesis by Regulating Pre-mRNA Splicing. Cell Rep. 2017 Jan 10;18(2):545-56.   PMCID: PMC5234864
Zhou C, Martinez E, Di Marcantonio D, Solanki-Patel N, Aghayev T, Peri S, Ferraro F, Skorski T, Scholl C, Frohling S, Balachandran S, Wiest DL, Sykes SM. JUN is a key transcriptional regulator of the unfolded protein response in acute myeloid leukemia. Leukemia. 2017 May;31(5):1196-205.   PMCID: PMC5473421
Zhou C, Martinez E, Di Marcantonio D, Solanki-Patel N, Aghayev T, Peri S, Ferraro F, Skorski T, Scholl C, Frohling S, Balachandran S, Wiest DL, Sykes SM. JUN is a key transcriptional regulator of the unfolded protein response in acute myeloid leukemia. Leukemia. 2017 May;31(5):1196-205.
Punwani D, Zhang Y, Yu J, Cowan MJ, Rana S, Kwan A, Adhikari AN, Lizama CO, Mendelsohn BA, Fahl SP, Chellappan A, Srinivasan R, Brenner SE, Wiest DL, Puck JM. Multisystem Anomalies in Severe Combined Immunodeficiency with Mutant BCL11B. The New England journal of medicine. 2016 Dec;375(22):2165-76.   PMCID: PMC5215776
Rao S, Cai KQ, Stadanlick JE, Greenberg-Kushnir N, Solanki-Patel N, Lee SY, Fahl SP, Testa JR, Wiest DL. Ribosomal Protein Rpl22 Controls the Dissemination of T-cell Lymphoma. Cancer Res. 2016 Jun;76(11):3387-96.   PMCID: PMC4891229
Simon AJ, Lev A, Zhang Y, Weiss B, Rylova A, Eyal E, Kol N, Barel O, Cesarkas K, Soudack M, Greenberg-Kushnir N, Rhodes M, Wiest DL, Schiby G, Barshack I, Katz S, Pras E, Poran H, Reznik-Wolf H, Ribakovsky E, Simon C, Hazou W, Sidi Y, Lahad A, Katzir H, Sagie S, Aqeilan HA, Glousker G, Amariglio N, Tzfati Y, Selig S, Rechavi G, Somech R. Mutations in STN1 cause Coats plus syndrome and are associated with genomic and telomere defects. J Exp Med. 2016 Jul 25;213(8):1429-40.   PMCID: PMC4986528
Solanki NR, Stadanlick JE, Zhang Y, Duc AC, Lee SY, Lauritsen JP, Zhang Z, Wiest DL. Rpl22 Loss Selectively Impairs alphabeta T Cell Development by Dysregulating Endoplasmic Reticulum Stress Signaling. J Immunol. 2016 Aug 03;197(6):2280-9.   PMCID: PMC5011012
Tan YF, Xin XB, Coffey FJ, Wiest DL, Dong LQ, Testa JR. Appl1 and Appl2 are Expendable for Mouse Development But Are Essential for HGF-Induced Akt Activation and Migration in Mouse Embryonic Fibroblasts. J Cell Physiol. 2016 May;231(5):1142-50.
Tan Y, Xin X, Coffey FJ, Wiest DL, Dong LQ, Testa JR. Appl1 and Appl2 are Expendable for Mouse Development But Are Essential for HGF-Induced Akt Activation and Migration in Mouse Embryonic Fibroblasts. Journal of cellular physiology. 2016 Oct 07;231(5):1142-50.   PMCID: PMC4728037
Wang Y, Bernhardy AJ, Cruz C, Krais JJ, Nacson J, Nicolas E, Peri S, van der Gulden H, van der Heijden I, O'Brien SW, Zhang Y, Harrell MI, Johnson SF, Candido Dos Reis FJ, Pharoah PD, Karlan B, Gourley C, Lambrechts D, Chenevix-Trench G, Olsson H, Benitez JJ, Greene MH, Gore M, Nussbaum R, Sadetzki S, Gayther SA, Kjaer SK, D'Andrea AD, Shapiro GI, Wiest DL, Connolly DC, Daly MB, Swisher EM, Bouwman P, Jonkers J, Balmana J, Serra V, Johnson N. The BRCA1-Delta11q Alternative Splice Isoform Bypasses Germline Mutations and Promotes Therapeutic Resistance to PARP Inhibition and Cisplatin. Cancer Res. 2016 May;76(9):2778-90.   PMCID: PMC4874568
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Last updated on Tuesday, June 05, 2018