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Jean P Issa

Center AffiliationsCancer Epigenetics

Publications (56) (print view)

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Laumet G, Garriga J, Chen SR, Zhang Y, Li DP, Smith TM, Dong Y, Jelinek J, Cesaroni M, Issa JP, Pan HL. G9a is essential for epigenetic silencing of K(+) channel genes in acute-to-chronic pain transition. Nat Neurosci. 2015 Dec;18(12):1746-55.   PMCID: PMC4661086
Lowder JN, Taverna P, Issa JJ. Will next-generation agents deliver on the promise of epigenetic hypomethylation therapy?. Epigenomics. 2015 Nov 06;7(7):1083-8.
Malouf GG, Tahara T, Paradis V, Fabre M, Guettier C, Yamazaki J, Long H, Lu Y, Raynal NJ, Jelinek J, Mouawad R, Khayat D, Brugieres L, Raymond E, Issa JP. Methylome sequencing for fibrolamellar hepatocellular carcinoma depicts distinctive features. Epigenetics. 2015 Sep 02;10(9):872-81.
Qin T, Si J, Raynal NJ, Wang X, Gharibyan V, Ahmed S, Hu X, Jin C, Lu Y, Shu J, Estecio MR, Jelinek J, Issa JP. Epigenetic synergy between decitabine and platinum derivatives. Clinical epigenetics. 2015 Jan;7(1):97.   PMCID: PMC4567801
Tsimberidou AM, Said R, Culotta K, Wistuba I, Jelinek J, Fu S, Falchook G, Naing A, Piha-Paul S, Zinner R, Siddik ZH, He G, Hess K, Stewart DJ, Kurzrock R, Issa JP. Phase I study of azacitidine and oxaliplatin in patients with advanced cancers that have relapsed or are refractory to any platinum therapy. Clin Epigenetics. 2015 Jan;7(1):29.
van Esterik JC, Vitins AP, Hodemaekers HM, Kamstra JH, Legler J, Pennings JL, Steegenga WT, Lute C, Jelinek J, Issa JP, Dolle ME, van der Ven LT. Liver DNA methylation analysis in adult female C57BL/6JxFVB mice following perinatal exposure to bisphenol A. Toxicology letters. 2015 Jan 05;232(1):293-300.
Yamazaki J, Jelinek J, Lu Y, Cesaroni M, Madzo J, Neumann F, He R, Taby R, Vasanthakumar A, Macrae T, Ostler KR, Kantarjian HM, Liang S, Estecio MR, Godley LA, Issa JP. TET2 mutations affect non-CpG island DNA methylation at enhancers and transcription factor binding sites in chronic myelomonocytic leukemia. Cancer Res. 2015 May 13;75(14):2833-43.   PMCID: 4506197
Yamazaki J, Taby R, Jelinek J, Raynal NJ, Cesaroni M, Pierce SA, Kornblau SM, Bueso-Ramos CE, Ravandi F, Kantarjian HM, Issa JP. Hypomethylation of TET2 Target Genes Identifies a Curable Subset of Acute Myeloid Leukemia. Journal of the National Cancer Institute. 2015 Nov 13;108(2).   PMCID: 4862435
Plimack ER, Desai JR, Issa JP, Jelinek J, Sharma P, Vence LM, Bassett RL, Ilagan JL, Papadopoulos NE, Hwu WJ. A phase I study of decitabine with pegylated interferon alpha-2b in advanced melanoma: impact on DNA methylation and lymphocyte populations. Invest New Drugs. 2014 Oct;32(5):969-75.
Plimack ER, Desai JR, Issa JP, Jelinek J, Sharma P, Vence LM, Bassett RL, Ilagan JL, Papadopoulos NE, Hwu WJ. A phase I study of decitabine with pegylated interferon α-2b in advanced melanoma: Impact on DNA methylation and lymphocyte populations. Investigational New Drugs. 2014 Oct;32(5):969-75.   PMCID: 4171200
Stewart DJ, Nunez MI, Jelinek J, Hong D, Gupta S, Aldaz M, Issa JP, Kurzrock R, Wistuba. Impact of decitabine on immunohistochemistry expression of the putative tumor suppressor genes FHIT, WWOX, FUS1 and PTEN in clinical tumor samples. Clin Epigenetics. 2014 Jan;6(1):13.   PMCID: Pmc4094901
Stewart DJ, Nunez MI, Jelinek J, Hong D, Gupta S, Issa JP, Wistuba, Kurzrock R. Decitabine impact on the endocytosis regulator RhoA, the folate carriers RFC1 and FOLR1, and the glucose transporter GLUT4 in human tumors. Clin Epigenetics. 2014 Jan;6(1):2.   PMCID: Pmc3895853
Estecio MR, Gallegos J, Dekmezian M, Lu Y, Liang S, Issa JP. SINE retrotransposons cause epigenetic reprogramming of adjacent gene promoters. Molecular cancer research : MCR. 2012 Oct;10(10):1332-42.   PMCID: Pmc3475755
Engstrom PF. Cancer Prevention and Control Priorities for the Year-2000 - a Commentary. Cancer. 1994 Aug 15;74(4):1433-7.
Fan JB, Deyoung J, Lagace R, Lina RA, Xu ZD, Murray JC, Buetow KH, Weissenbach J, Goold RD, Cox DR, Myers RM. Isolation of Yeast Artificial Chromosome Clones from 54 Polymorphic Loci Mapped with High Odds on Human-Chromosome-4. Human molecular genetics. 1994 Feb;3(2):243-6.
Feitelson M, Lega L, Guo JH, Resti M, Rossi ME, Azzari C, Blumberg BS, Vierucci A. Pathogenesis of Posttransfusion Viral-Hepatitis in Children with Beta-Thalassemia. Hepatology (Baltimore, Md). 1994 Mar;19(3):558-68.
Fenning MC, Brown DQ, Chapman JD. Photodosimetry of Interstitial Light Delivery to Solid Tumors. Medical Physics. 1994 Jul;21(7):1149-56.
Flubacher MM, Bear SE, Tsichlis PN. Replacement of Interleukin-2 (Il-2)-Generated Mitogenic Signals by a Mink Cell Focus-Forming (Mcf) or Xenotropic Virus-Induced Il-9-Dependent Autocrine Loop - Implications for Mcf Virus- Induced Leukemogenesis. Journal of Virology. 1994 Dec;68(12):7709-16.
Gasser DL, Sternberg NL, Pierce JC, Goldnersauve A, Feng H, Haq AK, Spies T, Hunt C, Buetow KH, Chaplin DD. P1 and Cosmid Clones Define the Organization of 280 Kb of the Mouse H-2-Complex Containing the Cps-1 and Hsp70 Loci. Immunogenetics. 1994 Jan;39(1):48-55.
Glusker JP. Untitled. Acta Crystallographica Section D-Biological Crystallography. 1994 Jan;50:1.
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Last updated on Tuesday, June 05, 2018