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Lawrence Goldfinger

Email
Center AffiliationsCancer Biology

Publications (18) (print view)

Michael JV, Goldfinger LE. Concepts and advances in cancer therapeutic vulnerabilities in RAS membrane targeting. Semin Cancer Biol. 2019 Feb;54:121-30.   PMCID: PMC5984110
Patel A, Kostyak J, Dangelmaier C, Badolia R, Bhavanasi D, Aslan JE, Merali S, Kim S, Eble JA, Goldfinger L, Kunapuli S. ELMO1 deficiency enhances platelet function. Blood advances. 2019 Feb 26;3(4):575-87.   PMCID: PMC6391667
Jalagadugula G, Goldfinger LE, Mao G, Lambert MP, Rao AK. Defective RAB1B-related megakaryocytic ER-to-Golgi transport in RUNX1 haplodeficiency: impact on von Willebrand factor. Blood advances. 2018 Apr 10;2(7):797-806.   PMCID: PMC5894258
Janapati S, Wurtzel J, Dangelmaier C, Manne BK, Bhavanasi D, Kostyak JC, Kim S, Holinstat M, Kunapuli SP, Goldfinger LE. TC21/RRas2 regulates glycoprotein VI--FcRgamma-mediated platelet activation and thrombus stability. Journal of thrombosis and haemostasis : JTH. 2018 Jun 08;.   PMCID: PMC6286703
Lazar S, Goldfinger LE. Platelet Microparticles and miRNA Transfer in Cancer Progression: Many Targets, Modes of Action, and Effects Across Cancer Stages. Frontiers in cardiovascular medicine. 2018 Feb;5:13.   PMCID: PMC5850852
Goldfinger LE, Michael JV. Regulation of Ras signaling and function by plasma membrane microdomains. Bioscience trends. 2017 Mar 22;11(1):23-40.   PMCID: Review
Mao GF, Goldfinger LE, Fan DC, Lambert MP, Jalagadugula G, Freishtat R, Rao AK. Dysregulation of PLDN (pallidin) is a mechanism for platelet dense granule deficiency in RUNX1 haplodeficiency. Journal of thrombosis and haemostasis : JTH. 2017 Apr;15(4):792-801.   PMCID: PMC5378588
Mao G, Songdej N, Voora D, Goldfinger LE, Del Carpio-Cano FE, Myers RA, Rao AK. Transcription Factor RUNX1 Regulates Platelet PCTP (Phosphatidylcholine Transfer Protein): Implications for Cardiovascular Events: Differential Effects of RUNX1 Variants. Circulation. 2017 Sep 05;136(10):927-39.   PMCID: PMC5591032
Michael JV, Goldfinger LE. Concepts and advances in cancer therapeutic vulnerabilities in RAS membrane targeting. Semin Cancer Biol. 2017 Dec;.   PMCID: PMC5984110
Michael JV, Wurtzel JG, Mao GF, Rao AK, Kolpakov MA, Sabri A, Hoffman NE, Rajan S, Tomar D, Madesh M, Nieman MT, Yu J, Edelstein LC, Rowley JW, Weyrich AS, Goldfinger LE. Platelet microparticles infiltrating solid tumors transfer miRNAs that suppress tumor growth. Blood. 2017 Aug 03;130(5):567-80.   PMCID: PMC5542851
Michael JV, Wurtzel JG, Goldfinger LE. Inhibition of Galectin-1 Sensitizes HRAS-driven Tumor Growth to Rapamycin Treatment. Anticancer research. 2016 Oct;36(10):5053-61.
Michael JV, Wurtzel JG, Goldfinger LE. Regulation of H-Ras-driven MAPK signaling, transformation and tumorigenesis, but not PI3K signaling and tumor progression, by plasma membrane microdomains. Oncogenesis. 2016 May;5(5):e228.   PMCID: PMC4945753
Rowley JW, Chappaz S, Corduan A, Chong MM, Campbell R, Khoury A, Manne BK, Wurtzel JG, Michael JV, Goldfinger LE, Mumaw MM, Nieman MT, Kile BT, Provost P, Weyrich AS. Dicer1-mediated miRNA processing shapes the mRNA profile and function of murine platelets. Blood. 2016 Apr 07;127(14):1743-51.   PMCID: PMC4825412
Wurtzel JG, Lee S, Singhal SS, Awasthi S, Ginsberg MH, Goldfinger LE. RLIP76 regulates Arf6-dependent cell spreading and migration by linking ARNO with activated R-Ras at recycling endosomes. Biochem Biophys Res Commun. 2015 Nov 27;467(4):785-91.   PMCID: 4644438
Lee S, Goldfinger LE. RLIP76 regulates HIF-1 activity, VEGF expression and secretion in tumor cells, and secretome transactivation of endothelial cells. FASEB J. 2014 Sep;28(9):4158-68.   PMCID: 4139904
Lee S, Wurtzel JG, Goldfinger LE. The RLIP76 N-terminus binds ARNO to regulate PI 3-kinase, Arf6 and Rac signaling, cell spreading and migration. Biochem Biophys Res Commun. 2014 Oct 30;454(4):560-5.   PMCID: Pmc4254618
Silver L, Michael JV, Goldfinger LE, Gallo G. Activation of PI3K and R-Ras signaling promotes the extension of sensory axons on inhibitory chondroitin sulfate proteoglycans. Dev Neurobiol. 2014 Sep;74(9):918-33.   PMCID: 4235675
Das IJ, McGee KP, Fein DA, Milito SJ, Shammo G, Curran WJ, Coia LR. Use of Multiplanar Reformatted Radiographic and Digitally Reconstructed Radiographic Images for Planning Conformal Radiation-Therapy. Radiographics. 1995 Nov;15(6):1483-8.
The above publications are sorted by year, faculty last name, and first author. Click on any highlighted author listed to find all publications attributed to that individual. Click on the publication title to see the abstract. First authors who are faculty are highlighted like this. Last authors who are faculty are highlighted like this. Other authors who are faculty are highlighted like this.

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Last updated on Friday, December 06, 2019