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Magid Abou-Gharbia

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Center AffiliationsMolecular Therapeutics

Publications (23) (print view)

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Al-Ashmawy AA, Ragab FA, Elokely KM, Anwar MM, Perez-Leal O, Rico MC, Gordon J, Bichenkov E, Mateo G, Kassem EM, Hegazy GH, Abou-Gharbia M, Childers W. Design, synthesis and SAR of new-di-substituted pyridopyrimidines as ATP-competitive dual PI3Kalpha/mTOR inhibitors. Bioorganic & medicinal chemistry letters. 2017 Jul 15;27(14):3117-22.
Bryant KG, Chae YC, Martinez RL, Gordon JC, Elokely KM, Kossenkov AV, Grant S, Childers WE, Abou-Gharbia M, Altieri DC. A Mitochondrial-targeted purine-based HSP90 antagonist for leukemia therapy. Oncotarget. 2017 Dec 22;8(68):112184-98.   PMCID: PMC5762502
Coric P, Saribas AS, Abou-Gharbia M, Childers W, Condra JH, White MK, Safak M, Bouaziz S. Nuclear Magnetic Resonance Structure of the Human Polyoma JC Virus Agnoprotein. Journal of cellular biochemistry. 2017 Oct;118(10):3268-80.   PMCID: PMC5550335
Di Meco A, Li JG, Blass BE, Abou-Gharbia M, Lauretti E, Pratico D. 12/15-Lipoxygenase Inhibition Reverses Cognitive Impairment, Brain Amyloidosis, and Tau Pathology by Stimulating Autophagy in Aged Triple Transgenic Mice. Biological psychiatry. 2017 Jan 15;81(2):92-100.
Kurimchak AM, Shelton C, Duncan KE, Johnson KJ, Brown J, O'Brien S, Gabbasov R, Fink LS, Li Y, Lounsbury N, Abou-Gharbia M, Childers WE, Connolly DC, Chernoff J, Peterson JR, Duncan JS. Resistance to BET Bromodomain Inhibitors Is Mediated by Kinome Reprogramming in Ovarian Cancer. Cell Rep. 2016 Aug 02;16(5):1273-86.   PMCID: PMC4972668
Raynal NJ, Lee JT, Wang Y, Beaudry A, Madireddi P, Garriga J, Malouf GG, Dumont S, Dettman EJ, Gharibyan V, Ahmed S, Chung W, Childers WE, Abou-Gharbia M, Henry RA, Andrews AJ, Jelinek J, Cui Y, Baylin SB, Gill DL, Issa JP. Targeting Calcium Signaling Induces Epigenetic Reactivation of Tumor Suppressor Genes in Cancer. Cancer Res. 2016 Mar 15;76(6):1494-505.   PMCID: PMC4794357
Saribas AS, Coric P, Hamazaspyan A, Davis W, Axman R, White MK, Abou-Gharbia M, Childers W, Condra JH, Bouaziz S, Safak M. Emerging From the Unknown: Structural and Functional Features of Agnoprotein of Polyomaviruses. Journal of cellular physiology. 2016 Oct;231(10):2115-27.   PMCID: PMC5217748
Chu J, Li JG, Giannopoulos PF, Blass BE, Childers W, Abou-Gharbia M, Pratico D. Pharmacologic blockade of 12/15-lipoxygenase ameliorates memory deficits, Abeta and tau neuropathology in the triple-transgenic mice. Mol Psychiatry. 2015 Nov;20(11):1329-38.
Chu J, Li JG, Giannopoulos PF, Blass BE, Childers W, Abou-Gharbia M, Pratico D. Pharmacologic blockade of 12/15-lipoxygenase ameliorates memory deficits, Abeta and tau neuropathology in the triple-transgenic mice. Molecular psychiatry. 2015 Jan 06;.
Eidem TM, Lounsbury N, Emery JF, Bulger J, Smith A, Abou-Gharbia M, Childers W, Dunman PM. Small-molecule inhibitors of Staphylococcus aureus RnpA-mediated RNA turnover and tRNA processing. Antimicrob Agents Chemother. 2015 Apr;59(4):2016-28.   PMCID: PMC4356807
Lounsbury N, Mateo G, Jones B, Papaiahgari S, Thimmulappa RK, Teijaro C, Gordon J, Korzekwa K, Ye M, Allaway G, Abou-Gharbia M, Biswal S, Childers W. Heterocyclic chalcone activators of nuclear factor (erythroid-derived 2)-like 2 (Nrf2) with improved in vivo efficacy. Bioorg Med Chem. 2015 Sep;23(17):5352-9.
Lounsbury N, Mateo G, Jones B, Papaiahgari S, Thimmulappa RK, Teijaro C, Gordon J, Korzekwa K, Ye M, Allaway G, Abou-Gharbia M, Biswal S, Childers W. Heterocyclic chalcone activators of nuclear factor (erythroid-derived 2)-like 2 (Nrf2) with improved in vivo efficacy. Bioorg Med Chem. 2015 Sep;23(17):5352-9.
Abou-Gharbia M, Childers WE. Discovery of innovative therapeutics: today's realities and tomorrow's vision. 1. Criticisms faced by the pharmaceutical industry. J Med Chem. 2013 Jul 25;56(14):5659-72.
McCall AM, Amoroso AR, Sautes C, Marks JD, Weiner LM. Characterization of anti-mouse Fc gamma RII single-chain Fv fragments derived from human phage display libraries. Immunotechnology. 1998 Jun;4(1):71-87.
McGuire WP, Ozols RF. Chemotherapy of advanced ovarian cancer (vol 25, pg 340, 1998). Seminars in Oncology. 1998 Dec;25(6):707.
McGuire WP, Ozols RF. Chemotherapy of advanced ovarian cancer. Seminars in Oncology. 1998 Jun;25(3):340-8.
Meropol NJ. Oral fluoropyrimidines in the treatment of colorectal cancer. European Journal of Cancer. 1998 Sep;34(10):1509-13.
Mgbonyebi OP, Russo J, Russo IH. Roscovitine inhibits the proliferative activity of immortal and neoplastic human breast epithelial cells. Anticancer research. 1998 Mar;18(2A):751-5.
Mgbonyebi OP, Russo J, Russo IH. Antiproliferative effect of synthetic resveratrol on human breast epithelial cells. International Journal of Oncology. 1998 Apr;12(4):865-9.
Miller SM, Mischel W, Schroeder CM, Buzaglo JS, Hurley K, Schreiber P, Mangan CE. Intrusive and avoidant ideation among females pursuing infertility treatment. Psychology & Health. 1998 Jan;13(5):847-58.
The above publications are sorted by year, faculty last name, and first author. Click on any highlighted author listed to find all publications attributed to that individual. Click on the publication title to see the abstract. First authors who are faculty are highlighted like this. Last authors who are faculty are highlighted like this. Other authors who are faculty are highlighted like this.

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Last updated on Friday, February 02, 2018