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Siddharth Balachandran

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Center AffiliationsBlood Cell Development and Function

Publications (51) (print view)

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Mamrot J, Balachandran S, Steele EJ, Lindley RA. Molecular model linking Th2 polarized M2 Tumor Associated Macrophages (TAMs) with deaminase-mediated cancer progression mutation signatures. Scandinavian journal of immunology. 2019 Feb 25;:e12760.
Di Marcantonio D, Martinez E, Sidoli S, Vadaketh J, Nieborowska-Skorska M, Gupta A, Meadows JM, Ferraro F, Masselli E, Challen GA, Milsom MD, Scholl C, Froehling S, Balachandran S, Skorski T, Garcia B, Mirandola P, Gobbi G, Garzon R, Vitale M, Sykes SM. PKC epsilon is a Key Regulator of Mitochondrial Redox Homeostasis in Acute Myeloid Leukemia. Clin Cancer Res. 2018 Feb;24(3):608-18.   PMCID: PMC5796864
Ingram JP, Tursi S, Zhang T, Guo W, Yin C, A Wynosky-Dolfi M, van der Heijden J, Cai KQ, Yamamoto M, Finlay BB, Brodsky IE, Grivennikov SI, Tukel C, Balachandran S. A Nonpyroptotic IFN-gamma-Triggered Cell Death Mechanism in Nonphagocytic Cells Promotes Salmonella Clearance In Vivo. J Immunol. 2018 May 15;200(10):3626-34.   PMCID: PMC6034694
Ingram JP, Tursi S, Zhang T, Guo W, Yin C, Wynosky-Dolfi MA, Van der Heijden J, Cai KQ, Yamamoto M, Brett Finlay B, Brodsky IE, Grivennikov SI, TĂĽkel Ă, Balachandran S. A nonpyroptotic ifn-g–triggered cell death mechanism in nonphagocytic cells promotes salmonella clearance in vivo. Journal of Immunology. 2018 Jan;200(10):3626-34.
Olagnier D, Brandtoft AM, Gunderstofte C, Villadsen NL, Krapp C, Thielke AL, Laustsen A, Peri S, Hansen AL, Bonefeld L, Thyrsted J, Bruun V, Iversen MB, Lin L, Artegoitia VM, Su C, Yang L, Lin R, Balachandran S, Luo Y, Nyegaard M, Marrero B, Goldbach-Mansky R, Motwani M, Ryan DG, Fitzgerald KA, O'Neill LA, Hollensen AK, Damgaard CK, de Paoli FV, Bertram HC, Jakobsen MR, Poulsen TB, Holm CK. Nrf2 negatively regulates STING indicating a link between antiviral sensing and metabolic reprogramming. Nat Commun. 2018 Aug 29;9(1):3506.   PMCID: PMC6115435
Thapa RJ, Nogusa S, Balachandran S. Analysis of Cytokine- and Influenza A Virus-Driven RIPK3 Necrosome Formation. Methods Mol Biol. 2018 Aug;1857:93-9.
von Massenhausen A, Tonnus W, Himmerkus N, Parmentier S, Saleh D, Rodriguez D, Ousingsawat J, Ang RL, Weinberg JM, Sanz AB, Ortiz A, Zierleyn A, Becker JU, Baratte B, Desban N, Bach S, Schiessl IM, Nogusa S, Balachandran S, Anders HJ, Ting AT, Bleich M, Degterev A, Kunzelmann K, Bornstein SR, Green DR, Hugo C, Linkermann A. Phenytoin inhibits necroptosis. Cell death & disease. 2018 Mar 02;9(3):359.   PMCID: PMC5834524
von Massenhausen A, Tonnus W, Himmerkus N, Parmentier S, Saleh D, Rodriguez D, Ousingsawat J, Ang RL, Weinberg JM, Sanz AB, Ortiz A, Zierleyn A, Becker JU, Baratte B, Desban N, Bach S, Schiessl IM, Nogusa S, Balachandran S, Anders HJ, Ting AT, Bleich M, Degterev A, Kunzelmann K, Bornstein SR, Green DR, Hugo C, Linkermann A. Correction to: Phenytoin inhibits necroptosis. Cell death & disease. 2018 May 24;9(6):622.   PMCID: PMC5967310
Choi YB, Shembade N, Parvatiyar K, Balachandran S, Harhaj EW. TAX1BP1 Restrains Virus-Induced Apoptosis by Facilitating Itch-Mediated Degradation of the Mitochondrial Adaptor MAVS. Mol Cell Biol. 2017 Jan;37(1).   PMCID: PMC5192085
Hartmann BM, Albrecht RA, Zaslavsky E, Nudelman G, Pincas H, Marjanovic N, Schotsaert M, Martinez-Romero C, Fenutria R, Ingram JP, Ramos I, Fernandez-Sesma A, Balachandran S, Garcia-Sastre A, Sealfon SC. Pandemic H1N1 influenza A viruses suppress immunogenic RIPK3-driven dendritic cell death. Nat Commun. 2017 Dec 05;8(1):1931.   PMCID: PMC5715119
Ingram JP, Brodsky IE, Balachandran S. Interferon-gamma in Salmonella pathogenesis: New tricks for an old dog. Cytokine. 2017 Oct 20;98:27-32.   PMCID: PMC5398957
Ingram JP, Brodsky IE, Balachandran S. Interferon-gamma in Salmonella pathogenesis: New tricks for an old dog. Cytokine. 2017 Oct;98:27-32.   PMCID: PMC5398957
Saleh D, Najjar M, Zelic M, Shah S, Nogusa S, Polykratis A, Paczosa MK, Gough PJ, Bertin J, Whalen M, Fitzgerald KA, Slavov N, Pasparakis M, Balachandran S, Kelliher M, Mecsas J, Degterev A. Kinase Activities of RIPK1 and RIPK3 Can Direct IFN-beta Synthesis Induced by Lipopolysaccharide. J Immunol. 2017 Jun;198(11):4435-47.   PMCID: PMC5471631
Upton JW, Shubina M, Balachandran S. RIPK3-driven cell death during virus infections. Immunological reviews. 2017 May;277(1):90-101.   PMCID: REVIEW
Zhou C, Martinez E, Di Marcantonio D, Solanki-Patel N, Aghayev T, Peri S, Ferraro F, Skorski T, Scholl C, Frohling S, Balachandran S, Wiest DL, Sykes SM. JUN is a key transcriptional regulator of the unfolded protein response in acute myeloid leukemia. Leukemia. 2017 May;31(5):1196-205.   PMCID: PMC5473421
Zhou C, Martinez E, Di Marcantonio D, Solanki-Patel N, Aghayev T, Peri S, Ferraro F, Skorski T, Scholl C, Frohling S, Balachandran S, Wiest DL, Sykes SM. JUN is a key transcriptional regulator of the unfolded protein response in acute myeloid leukemia. Leukemia. 2017 May;31(5):1196-205.
Corradetti C, Jog NR, Gallucci S, Madaio M, Balachandran S, Caricchio R. Immune-Mediated Nephropathy and Systemic Autoimmunity in Mice Does Not Require Receptor Interacting Protein Kinase 3 (RIPK3). PLoS One. 2016 Sep;11(9):e0163611.   PMCID: PMC5036882
Dillon CP, Balachandran S. StIKKing it to a death kinase: IKKs prevent TNF-α-induced cell death by phosphorylating RIPK1. Cytokine. 2016 Feb;78:47-50.   PMCID: Comment
Gopas J, Stern E, Zurgil U, Ozer J, Ben-Ari A, Shubinsky G, Braiman A, Sinay R, Ezratty J, Dronov V, Balachandran S, Benharroch D, Livneh E. Reed-Sternberg cells in Hodgkin's lymphoma present features of cellular senescence. Cell death & disease. 2016 Nov 10;7(11):e2457.   PMCID: PMC5287295
Najjar M, Saleh D, Zelic M, Nogusa S, Shah S, Tai A, Finger JN, Polykratis A, Gough PJ, Bertin J, Whalen MJ, Pasparakis M, Balachandran S, Kelliher M, Poltorak A, Degterev A. RIPK1 and RIPK3 Kinases Promote Cell-Death-Independent Inflammation by Toll-like Receptor 4. Immunity. 2016 Jul 19;45(1):46-59.   PMCID: PMC4956514
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Last updated on Thursday, May 02, 2019