Siddharth Balachandran
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Balachandran S, Rall GF. The Benefits and Perils of Necroptosis in Influenza Infection. J Virol. 2020 Feb 12;.
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Jain R, Vijayvergia N, Devarajan K, Lewis B, Denlinger CS, Cohen SJ, Dotan E. Chemotherapy use and survival in older adults with metastatic pancreatic cancer in the combination therapy era. Journal of geriatric oncology. 2020 Jan;.
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Gunderstofte C, Iversen MB, Peri S, Thielke A, Balachandran S, Holm CK, Olagnier D. Nrf2 Negatively Regulates Type I Interferon Responses and Increases Susceptibility to Herpes Genital Infection in Mice. Frontiers in immunology. 2019 Jan;10:2101.
PMCID: PMC6742979
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Ingram JP, Thapa RJ, Fisher A, Tummers B, Zhang T, Yin C, Rodriguez DA, Guo H, Lane R, Williams R, Slifker MJ, Basagoudanavar SH, Rall GF, Dillon CP, Green DR, Kaiser WJ, Balachandran S. ZBP1/DAI Drives RIPK3-Mediated Cell Death Induced by IFNs in the Absence of RIPK1. J Immunol. 2019 Sep;203(5):1348-55.
PMCID: PMC6702065
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Mamrot J, Balachandran S, Steele EJ, Lindley RA. Molecular model linking Th2 polarized M2 Tumor Associated Macrophages (TAMs) with deaminase-mediated cancer progression mutation signatures. Scandinavian journal of immunology. 2019 May;89(5):e12760.
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Zhang T, Balachandran S. Bayonets over bombs: RIPK3 and MLKL restrict Listeria without triggering necroptosis. The Journal of cell biology. 2019 May 16;218(6):1773-5.
PMCID: Commentary
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Di Marcantonio D, Martinez E, Sidoli S, Vadaketh J, Nieborowska-Skorska M, Gupta A, Meadows JM, Ferraro F, Masselli E, Challen GA, Milsom MD, Scholl C, Froehling S, Balachandran S, Skorski T, Garcia B, Mirandola P, Gobbi G, Garzon R, Vitale M, Sykes SM. PKC epsilon is a Key Regulator of Mitochondrial Redox Homeostasis in Acute Myeloid Leukemia. Clin Cancer Res. 2018 Feb;24(3):608-18.
PMCID: PMC5796864
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Ingram JP, Tursi S, Zhang T, Guo W, Yin C, A Wynosky-Dolfi M, van der Heijden J, Cai KQ, Yamamoto M, Finlay BB, Brodsky IE, Grivennikov SI, Tukel C, Balachandran S. A Nonpyroptotic IFN-gamma-Triggered Cell Death Mechanism in Nonphagocytic Cells Promotes Salmonella Clearance In Vivo. J Immunol. 2018 May 15;200(10):3626-34.
PMCID: PMC6034694
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Ingram JP, Tursi S, Zhang T, Guo W, Yin C, Wynosky-Dolfi MA, Van der Heijden J, Cai KQ, Yamamoto M, Brett Finlay B, Brodsky IE, Grivennikov SI, TĂĽkel Ă, Balachandran S. A nonpyroptotic ifn-g–triggered cell death mechanism in nonphagocytic cells promotes salmonella clearance in vivo. Journal of Immunology. 2018 Jan;200(10):3626-34.
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Olagnier D, Brandtoft AM, Gunderstofte C, Villadsen NL, Krapp C, Thielke AL, Laustsen A, Peri S, Hansen AL, Bonefeld L, Thyrsted J, Bruun V, Iversen MB, Lin L, Artegoitia VM, Su C, Yang L, Lin R, Balachandran S, Luo Y, Nyegaard M, Marrero B, Goldbach-Mansky R, Motwani M, Ryan DG, Fitzgerald KA, O'Neill LA, Hollensen AK, Damgaard CK, de Paoli FV, Bertram HC, Jakobsen MR, Poulsen TB, Holm CK. Nrf2 negatively regulates STING indicating a link between antiviral sensing and metabolic reprogramming. Nat Commun. 2018 Aug 29;9(1):3506.
PMCID: PMC6115435
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Thapa RJ, Nogusa S, Balachandran S. Analysis of Cytokine- and Influenza A Virus-Driven RIPK3 Necrosome Formation. Methods Mol Biol. 2018 Aug;1857:93-9.
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von Massenhausen A, Tonnus W, Himmerkus N, Parmentier S, Saleh D, Rodriguez D, Ousingsawat J, Ang RL, Weinberg JM, Sanz AB, Ortiz A, Zierleyn A, Becker JU, Baratte B, Desban N, Bach S, Schiessl IM, Nogusa S, Balachandran S, Anders HJ, Ting AT, Bleich M, Degterev A, Kunzelmann K, Bornstein SR, Green DR, Hugo C, Linkermann A. Phenytoin inhibits necroptosis. Cell death & disease. 2018 Mar 02;9(3):359.
PMCID: PMC5834524
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von Massenhausen A, Tonnus W, Himmerkus N, Parmentier S, Saleh D, Rodriguez D, Ousingsawat J, Ang RL, Weinberg JM, Sanz AB, Ortiz A, Zierleyn A, Becker JU, Baratte B, Desban N, Bach S, Schiessl IM, Nogusa S, Balachandran S, Anders HJ, Ting AT, Bleich M, Degterev A, Kunzelmann K, Bornstein SR, Green DR, Hugo C, Linkermann A. Correction to: Phenytoin inhibits necroptosis. Cell death & disease. 2018 May 24;9(6):622.
PMCID: PMC5967310
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Choi YB, Shembade N, Parvatiyar K, Balachandran S, Harhaj EW. TAX1BP1 Restrains Virus-Induced Apoptosis by Facilitating Itch-Mediated Degradation of the Mitochondrial Adaptor MAVS. Mol Cell Biol. 2017 Jan;37(1).
PMCID: PMC5192085
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Hartmann BM, Albrecht RA, Zaslavsky E, Nudelman G, Pincas H, Marjanovic N, Schotsaert M, Martinez-Romero C, Fenutria R, Ingram JP, Ramos I, Fernandez-Sesma A, Balachandran S, Garcia-Sastre A, Sealfon SC. Pandemic H1N1 influenza A viruses suppress immunogenic RIPK3-driven dendritic cell death. Nat Commun. 2017 Dec 05;8(1):1931.
PMCID: PMC5715119
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Ingram JP, Brodsky IE, Balachandran S. Interferon-gamma in Salmonella pathogenesis: New tricks for an old dog. Cytokine. 2017 Oct 20;98:27-32.
PMCID: PMC5398957
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Ingram JP, Brodsky IE, Balachandran S. Interferon-gamma in Salmonella pathogenesis: New tricks for an old dog. Cytokine. 2017 Oct;98:27-32.
PMCID: PMC5398957
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Saleh D, Najjar M, Zelic M, Shah S, Nogusa S, Polykratis A, Paczosa MK, Gough PJ, Bertin J, Whalen M, Fitzgerald KA, Slavov N, Pasparakis M, Balachandran S, Kelliher M, Mecsas J, Degterev A. Kinase Activities of RIPK1 and RIPK3 Can Direct IFN-beta Synthesis Induced by Lipopolysaccharide. J Immunol. 2017 Jun;198(11):4435-47.
PMCID: PMC5471631
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Upton JW, Shubina M, Balachandran S. RIPK3-driven cell death during virus infections. Immunological reviews. 2017 May;277(1):90-101.
PMCID: REVIEW
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Zhou C, Martinez E, Di Marcantonio D, Solanki-Patel N, Aghayev T, Peri S, Ferraro F, Skorski T, Scholl C, Frohling S, Balachandran S, Wiest DL, Sykes SM. JUN is a key transcriptional regulator of the unfolded protein response in acute myeloid leukemia. Leukemia. 2017 May;31(5):1196-205.
PMCID: PMC5473421
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Siddharth Balachandran 
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