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Heinrich Roder

Center AffiliationsMolecular Therapeutics

Publications (92) (print view)

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Iwafuchi M, Cuesta I, Donahue G, Takenaka N, Osipovich AB, Magnuson MA, Roder H, Seeholzer SH, Santisteban P, Zaret KS. Gene network transitions in embryos depend upon interactions between a pioneer transcription factor and core histones. Nature genetics. 2020 Mar 16;52(4):418-27.
Bai N, Roder H, Dickson A, Karanicolas J. Isothermal Analysis of ThermoFluor Data can readily provide Quantitative Binding Affinities. Sci Rep. 2019 Feb 25;9(1):2650.   PMCID: PMC6389909
Cheng H, Schwell V, Curtis BR, Fazlieva R, Roder H, Campbell KS. Conformational Changes in the Cytoplasmic Region of KIR3DL1 upon Interaction with SHP-2. Structure (London, England : 1993). 2019 Feb 06;27(4):639-650 e2.   PMCID: PMC6447435
Mizukami T, Xu M, Fazlieva R, Bychkova VE, Roder H. Complex Folding Landscape of Apomyoglobin at Acidic pH Revealed by Ultrafast Kinetic Analysis of Core Mutants. J Phys Chem B. 2018 Aug 31;122(49):11228-39.   PMCID: PMC6395567
Rawat SJ, Araiza-Olivera D, Arias-Romero LE, Villamar-Cruz O, Prudnikova TY, Roder H, Chernoff J. H-ras Inhibits the Hippo Pathway by Promoting Mst1/Mst2 Heterodimerization. Curr Biol. 2016 May 26;26(12):1556-63.   PMCID: PMC4915977
Honda RP, Xu M, Yamaguchi K, Roder H, Kuwata K. A Native-like Intermediate Serves as a Branching Point between the Folding and Aggregation Pathways of the Mouse Prion Protein. Structure (London, England : 1993). 2015 Sep;23(9):1735-42.   PMCID: 4640677
Lehmann A, Wixted JH, Shapovalov MV, Roder H, Dunbrack RL, Robinson MK. Stability engineering of anti-EGFR scFv antibodies by rational design of a lambda-to-kappa swap of the VL framework using a structure-guided approach. MAbs. 2015 Nov 02;7(6):1058-71.   PMCID: 4966335
Wu Y, Span LM, Nygren P, Zhu H, Moore DT, Cheng H, Roder H, DeGrado WF, Bennett JS. The Tyrosine Kinase c-Src Specifically Binds to the Active Integrin alphaIIbbeta3 to Initiate Outside-In Signaling in Platelets. The Journal of biological chemistry. 2015 May 06;290(25):15825-34.   PMCID: 4505490
Fazelinia H, Xu M, Cheng H, Roder H. Ultrafast Hydrogen Exchange Reveals Specific Structural Events during the Initial Stages of Folding of Cytochrome c. Journal of the American Chemical Society. 2014 Jan;136(2):733-40.   PMCID: PMC 3956590
Montalvo GL, Gai F, Roder H, DeGrado WF. Slow Folding-Unfolding Kinetics of an Octameric beta-Peptide Bundle. ACS chemical biology. 2014 Jan;9(1):276-81.   PMCID: PMC 39470042
Wang J, Han X, Wong CC, Cheng H, Aslanian A, Xu T, Leavis P, Roder H, Hedstrom L, Yates JR, Kashina A. Arginyltransferase ATE1 catalyzes midchain arginylation of proteins at side chain carboxylates in vivo. Chem Biol. 2014 Mar 20;21(3):331-7.   PMCID: PMC4010198
Mizukami T, Xu M, Cheng H, Roder H, Maki K. Nonuniform chain collapse during early stages of staphylococcal nuclease folding detected by fluorescence resonance energy transfer and ultrarapid mixing methods. Protein Science. 2013 Oct;22(10):1336-48.   PMCID: PMC 3795492
Moroz OV, Moroz YS, Wu YB, Olsen AB, Cheng H, Mack KL, McLaughlin JM, Raymond EA, Zhezherya K, Roder H, Korendovych IV. A Single Mutation in a Regulatory Protein Produces Evolvable Allosterically Regulated Catalyst of Nonnatural Reaction. Angewandte Chemie-International Edition. 2013 Jan;52(24):6246-9.   PMCID: PMC3817844
Xu M, Beresneva O, Rosario R, Roder H. Microsecond Folding Dynamics of Apomyoglobin at Acidic pH. Journal of Physical Chemistry B. 2012 Jun;116(23):7014-25.   PMCID: PMC3480020
Chen KC, Xu M, Wedemeyer WJ, Roder H. Microsecond Unfolding Kinetics of Sheep Prion Protein Reveals an Intermediate that Correlates with Susceptibility to Classical Scrapie. Biophysical journal. 2011 Sep;101(5):1221-30.   PMCID: PMC3164147
Katz RA, Merkel G, Andrake MD, Roder H, Skalka AM. Retroviral Integrases Promote Fraying of Viral DNA Ends. Journal of Biological Chemistry. 2011 Jul;286(29):25710-8.   PMCID: PMC3138259
Korendovych IV, Kulp DW, Wu Y, Cheng H, Roder H, Degrado WF. Design of a switchable eliminase. Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):6823-7.   PMCID: PMC3084051
Alves C, Cheng H, Roder H, Taylor J. Intrinsic disorder and oligomerization of the hepatitis delta virus antigen. Virology. 2010 Nov 25;407(2):333-40.   PMCID: PMC2952689
Chung CH, Seeley EH, Roder H, Grigorieva J, Tsypin M, Roder J, Burtness BA, Argiris A, Forastiere AA, Gilbert J, Murphy B, Caprioli RM, Carbone DP, Cohen EE. Detection of tumor epidermal growth factor receptor pathway dependence by serum mass spectrometry in cancer patients. Cancer Epidemiol Biomarkers Prev. 2010 Feb;19(2):358-65.   PMCID: PMC2846615
Lau WL, DeGrado WF, Roder H. The Effects of pK(a) Tuning on the Thermodynamics and Kinetics of Folding: Design of a Solvent-Shielded Carboxylate Pair at the a-Position of a Coiled-Coil. Biophysical journal. 2010 Oct;99(7):2299-308.   PMCID: PMC3042555
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Last updated on Wednesday, July 08, 2020